Julie F Foley

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
    Tracy C DeLozier
    National Institute of Environmental Health Sciences, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    Drug Metab Dispos 35:682-8. 2007
  2. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
  3. pmc Optimal sampling of rat liver tissue for toxicogenomic studies
    Julie F Foley
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 34:795-801. 2006
  4. ncbi request reprint Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations
    Alexandra N Heinloth
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 35:276-83. 2007
  5. pmc Gastrointestinal hyperplasia with altered expression of DNA polymerase beta
    Katsuhiko Yoshizawa
    Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
    PLoS ONE 4:e6493. 2009
  6. pmc Testing an aflatoxin B1 gene signature in rat archival tissues
    B Alex Merrick
    Biomolecular Screening Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Chem Res Toxicol 25:1132-44. 2012
  7. pmc Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart
    Matthew L Edin
    Division of Intramural Research, National Institute for Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    FASEB J 25:3436-47. 2011
  8. ncbi request reprint Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats
    Katsuhiko Yoshizawa
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 85:594-606. 2005
  9. ncbi request reprint Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats
    Yoshiro Tani
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 32:41-9. 2004
  10. ncbi request reprint Ocular expression of vascular cell adhesion molecule (VCAM-1) in 2-butoxyethanol-induced hemolysis and thrombosis in female rats
    Abraham Nyska
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 9998, USA
    Exp Toxicol Pathol 55:231-6. 2003

Collaborators

Detail Information

Publications26

  1. pmc Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
    Tracy C DeLozier
    National Institute of Environmental Health Sciences, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    Drug Metab Dispos 35:682-8. 2007
    ..The expression of CYP2J2 and CYP2C8 in human heart, and CYPC9 and CYP2J2 in aorta and coronary artery is consistent with a physiological role for these enzymes in these tissues...
  2. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
    ..This study was designed to identify TLR4-mediated gene expression pathways that may be used as prognostic indicators of susceptibility to lung tumorigenesis in mice and provide insight into the mechanism...
  3. pmc Optimal sampling of rat liver tissue for toxicogenomic studies
    Julie F Foley
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 34:795-801. 2006
    ..Additionally, a powdered sample provided the advantages of a homogenous sample pool and the ability to use sample aliquots for other analyses to include proteomics, metabonomics, and other molecular techniques...
  4. ncbi request reprint Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations
    Alexandra N Heinloth
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 35:276-83. 2007
    ....
  5. pmc Gastrointestinal hyperplasia with altered expression of DNA polymerase beta
    Katsuhiko Yoshizawa
    Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
    PLoS ONE 4:e6493. 2009
    ..Altered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition resulting from Pol beta over-expression has not yet been evaluated in a mouse model...
  6. pmc Testing an aflatoxin B1 gene signature in rat archival tissues
    B Alex Merrick
    Biomolecular Screening Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Chem Res Toxicol 25:1132-44. 2012
    ..We conclude that an evaluation of gene signatures in archival tissues can be an important toxicological tool for evaluating critical molecular events associated with chemical exposures...
  7. pmc Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart
    Matthew L Edin
    Division of Intramural Research, National Institute for Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    FASEB J 25:3436-47. 2011
    ..These data demonstrate that increased ROS generation and enhanced DiHOME synthesis by endothelial CYP2C8 impair functional recovery and mask the beneficial effects of increased EET production following I/R...
  8. ncbi request reprint Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats
    Katsuhiko Yoshizawa
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 85:594-606. 2005
    ..Changes in the expression of CYP or CCKAR may have induced the acinar-cell tumors by initiating proliferation...
  9. ncbi request reprint Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats
    Yoshiro Tani
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 32:41-9. 2004
    ..These results indicate that the follicular cell response was hypertrophic and reversible. This information should contribute to diagnosis of nonneoplastic thyroid follicular lesions in rats...
  10. ncbi request reprint Ocular expression of vascular cell adhesion molecule (VCAM-1) in 2-butoxyethanol-induced hemolysis and thrombosis in female rats
    Abraham Nyska
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 9998, USA
    Exp Toxicol Pathol 55:231-6. 2003
    ..No change in ICAM-1 or P-selectin expression was seen. This immunolabeling distribution suggests that VCAM-1 functions in the pathogenesis of BE-related thrombosis by promoting adhesion of erythrocytes to the endothelium...
  11. pmc Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5
    Laura Wilding Crawford
    1Cellular and Molecular Pathology Branch, NIEHS, NIH, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 38:872-906. 2010
    ..Authors' note: All digital images can be viewed online at https://niehsimagesepl-inc.com with the username "ToxPathLiver" and the password "embryolivers."..
  12. ncbi request reprint Immunohistochemical markers for the rodent immune system
    Jerrold M Ward
    Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases NIH, Bethesda, MD 20892 8135, USA
    Toxicol Pathol 34:616-30. 2006
    ....
  13. ncbi request reprint Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine
    Abraham Nyska
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 83:388-96. 2005
    ..Our work shows the direct relationship between combined ephedrine and caffeine exposure and cardiac pathology...
  14. ncbi request reprint Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination
    Sherine S L Chan
    Laboratory of Molecular Genetics, National Institute of Environmental HealthSciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
    Environ Mol Mutagen 48:190-200. 2007
    ..Our data suggest that AZT/3TC combination treatment produces greater mtDNA damage than either agent individually, and that female mice are more sensitive than males to AZT/3TC-induced mtDNA damage...
  15. pmc Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5
    Saija M Savolainen
    NIEHS, Cellular and Molecular Pathology Branch, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 37:395-414. 2009
    ..5-18.5) is available on the CD enclosed in this issue of Toxicologic Pathology. All digital images can be viewed online at https://niehsimages.epl-inc.com with the username "ToxPath" and the password "embryohearts."..
  16. pmc The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens
    Rhonda H Wilson
    Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences NIEHS, National Institutes of Health, Research Triangle Park, NC, USA
    Nat Med 18:1705-10. 2012
    ..Together, these findings suggest that household FLA promotes the development of allergic asthma by TLR5-dependent priming of allergic responses to indoor allergens...
  17. pmc Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice
    Aparna Purushotham
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Mol Cell Biol 32:1226-36. 2012
    ..Taken together, our findings indicate that SIRT1 plays a vital role in the regulation of hepatic bile acid homeostasis through the HNF1α/FXR signaling pathway...
  18. pmc Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation
    Jeffrey W Card
    Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709
    J Immunol 177:4785-93. 2006
    ..Collectively, these data indicate that COX-1 overexpression attenuates airway responsiveness under basal conditions but does not influence allergic airway inflammation...
  19. ncbi request reprint The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, and p53 and hepatocytic vascular endothelial growth factor expression after short-term exposure
    Abraham Nyska
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Appl Pharmacol 184:153-64. 2002
    ..Endothelial proliferation may also have been promoted through endothelial arrest at S phase, which was associated with endothelial karyo- and cytomegaly, resulting in hepatocytic hypoxia, triggering VEGF induction...
  20. doi request reprint Apparent alveolar bronchiolar tumors arising in the mediastinum of F344 rats
    Paul Howroyd
    Experimental Pathology Laboratories, Inc, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 37:351-8. 2009
    ....
  21. ncbi request reprint Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice
    Robert W Sobol
    Laboratory of Structural Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    DNA Repair (Amst) 2:609-22. 2003
    ..These results suggest that either a beta-pol expression imbalance negatively affects overall fidelity and/or BER capacity or that beta-pol has a role in lens epithelial cell differentiation...
  22. ncbi request reprint Transplacental carcinogenicity of 3'-azido-3'-deoxythymidine in B6C3F1 mice and F344 rats
    Dale M Walker
    Experimental Pathology Laboratories, Inc, Herndon, Virginia, USA
    Environ Mol Mutagen 48:283-98. 2007
    ....
  23. ncbi request reprint Induction of interleukin-1beta, tumour necrosis factor-alpha and apoptosis in mouse organs by amphotericin B is neutralized by conjugation with arabinogalactan
    Rama Falk
    Department of Clinical Microbiology and Infectious Diseases, The Hebrew University Hadassah Medical Center, PO Box 12000, Jerusalem 91120, Israel
    J Antimicrob Chemother 55:713-20. 2005
    ....
  24. ncbi request reprint Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine
    Uri Wormser
    Department of Pharmacology, School of Pharmacy Faculty of Medicine, Berman Building, Institute of Life Sciences, The Hebrew University of Jerusalem, Givat Ram, 91904 Jerusalem, Israel
    Arch Toxicol 79:660-70. 2005
    ..The combination of iodine and antiTNF-alpha antibodies might constitute a new approach for treatment of SM-exposed individuals...
  25. ncbi request reprint Failure of catalase to protect against aflatoxin B1-induced mouse lung tumorigenicity
    Katherine A Guindon
    Department of Pharmacology and Toxicology, Queen s University, Kingston, Ontario, Canada K7L 3N6
    Toxicol Appl Pharmacol 227:179-83. 2008
    ..These results demonstrate that PEG-CAT is not protective against AFB(1) carcinogenicity in mouse lung despite preventing DNA oxidation...
  26. ncbi request reprint Comparative prevalence, multiplicity, and progression of spontaneous and vinyl carbamate-induced liver lesions in five strains of male mice
    Mimasa Takahashi
    Nippon Veterinary and Animal Science University, Tokyo, Japan
    Toxicol Pathol 30:599-605. 2002
    ....