Thomas R Fears
Affiliation: National Institutes of Health
- Identifying individuals at high risk of melanoma: a practical predictor of absolute riskThomas R Fears
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Clin Oncol 24:3590-6. 2006..We developed a model to estimate the 5-year absolute risk of melanoma to efficiently identify individuals at increased risk of melanoma for potential interventions...
- Average midrange ultraviolet radiation flux and time outdoors predict melanoma riskThomas R Fears
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 62:3992-6. 2002..4%). The association between melanoma risk and average annual UVB flux was strong and consistent for men and for women. The association with total adult hours outdoors was notable for men of all skin types and women who develop a suntan...
- Sunbeds and sunlamps: who used them and their risk for melanomaThomas R Fears
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Pigment Cell Melanoma Res 24:574-81. 2011..Body sites that are not generally exposed to sunlight were more common sites of primary melanomas for frequent sunbed/sunlamp users. For males, measures of sunbed/sunlamp use were not significantly associated with melanoma risk...
- Assessment of lifetime cumulative sun exposure using a self-administered questionnaire: reliability of two approachesChu Ling Yu
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 18:464-71. 2009..05); the higher ICCs for the activity-based questionnaire were primarily derived from the results for females. Research is needed to further improve the activity-based questionnaire approach for long-term sun exposure assessment...
- Endogenous sex hormones and the risk of prostate cancer: a prospective studyJocelyn M Weiss
Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD, USA
Int J Cancer 122:2345-50. 2008..T:SHBG ratio was related to risk in this older population of men, but the significance of this ratio in steroidal biology is unclear. (c) 2008 Wiley-Liss, Inc...
- IGF-1 and IGFBP-3: Risk of prostate cancer among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening TrialJocelyn M Weiss
Division of Cancer Epidemiology and Genetics, NCI NIH, Bethesda, MD, USA
Int J Cancer 121:2267-73. 2007..11-7.08). In summary, our large prospective study showed no overall association between the insulin-like growth factor axis and prostate cancer risk, however, IGFmr was related to risk for aggressive prostate cancer in obese men...
- Measurement of steroid sex hormones in serum: a comparison of radioimmunoassay and mass spectrometryJoanne F Dorgan
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Steroids 67:151-8. 2002..Relative power of studies using radioimmunoassay and mass spectrometry will depend on the hormones measured and their serum concentrations...
- Standard errors for attributable risk for simple and complex sample designsBarry I Graubard
Biostatistics Branch, National Cancer Institute, 6120 Executive Boulevard, Room 8024, Bethesda, Maryland 20892, USA
Biometrics 61:847-55. 2005....
- Urinary estrogen metabolites and their ratio among Asian American womenRoni T Falk
Environmental Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, MSC 7234, Suite 7070, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 14:221-6. 2005..Our study suggests that the ratio of 2-OHE(1):16alpha-OHE(1) may be a marker for lifestyle influences on estrogen metabolism associated with westernization...
- Agreement between contemporaneously recorded and subsequently recalled time spent outdoors: implications for environmental exposure studiesGabriel Chodick
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Ann Epidemiol 17:106-11. 2007..The aim of the study is to evaluate the agreement between contemporaneously recorded and subsequently recalled time spent outdoors during 1 week among members of an occupational cohort...
- Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United StatesOla Landgren
Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892 7236, USA
Blood 107:904-6. 2006..In the largest study to date, we suggest that the excess risk of MM in African Americans results from an increase in risk of MGUS rather than an increased risk of progression from MGUS to MM...
- Reproducibility of serum sex steroid assays in men by RIA and mass spectrometryAnn W Hsing
Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 5024, MSC 7234, 6120 Executive Boulevard, Bethesda, MD 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 16:1004-8. 2007....
- Nutritional and genetic inefficiencies in one-carbon metabolism and cervical cancer riskRegina G Ziegler
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
J Nutr 132:2345S-2349S. 2002....
- Reproducibility studies and interlaboratory concordance for androgen assays of male plasma hormone levelsThomas R Fears
Biostatistics Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 11:785-9. 2002..This reliability study design is, however, entirely appropriate for the typical case-control study which utilizes only one sample per subject...
- A reproducibility study for a fluoride assay in boneNancy Medina
NIH/National Cancer Institute, Biostatistics Branch, EPN 403, 6130 Executive Boulevard, MSC 7368, Bethesda, MD 20892-7368, USA
Cancer Epidemiol Biomarkers Prev 15:1035-7. 2006..Here, the estimated ICC is 0.86, and the estimated downward bias is only 14%. Hence, the ICC is strong enough so that the estimates of the relative risk will suffer little attenuation from lab measurements...
- Reproducibility and correlations of multiplex cytokine levels in asymptomatic personsHui Lee Wong
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, Room 7073, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:3450-6. 2008..Grossly elevated blood levels characterize certain diseases; variations within physiologic ranges could also have significance. We therefore evaluated the performance characteristics of a multiplex cytokine immunoassay...
- Deep vein thrombosis after monoclonal gammopathy of undetermined significance and multiple myelomaSigurdur Y Kristinsson
Department of Medicine, Division of Hematology, Karolinska University Hospital and Institutet, Stockholm, Sweden
Blood 112:3582-6. 2008..5%) that progressed to MM, only one person had a DVT diagnosis before transformation. Our findings suggest the operation of shared underlying mechanisms causing coagulation abnormalities among patients with MGUS and MM...
- Serum carotenoids and alpha-tocopherol and risk of nonmelanoma skin cancerJoanne F Dorgan
Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Cancer Epidemiol Biomarkers Prev 13:1276-82. 2004..Carotenoids and tocopherols have been hypothesized to protect against cancer...
- Pediatric melanoma: risk factor and survival analysis of the surveillance, epidemiology and end results databaseJohn J Strouse
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Clin Oncol 23:4735-41. 2005..To evaluate risk factors for the development of and factors influencing survival in pediatric melanoma...
- Immune thrombocytopenic purpura does not exhibit a disparity in prevalence between African American and White veteransOla Landgren
Blood 108:1111-2. 2006
- Re: Sun exposure and mortality from melanomaThomas R Fears
J Natl Cancer Inst 97:1789-90; author reply 1791. 2005
- Mice with genetically determined high susceptibility to ultraviolet (UV)-induced immunosuppression show enhanced UV carcinogenesisFrances P Noonan
Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, Washington, DC 20037, USA
J Invest Dermatol 121:1175-81. 2003..025). These findings support the concept that genetic differences in susceptibility to UV-induced immunosuppression may be a risk factor for skin cancer...
- Fertility of long-term male survivors of acute lymphoblastic leukemia diagnosed during childhoodJulianne Byrne
The Children s National Medical Center, Washington, DC 20010, USA
Pediatr Blood Cancer 42:364-72. 2004..However, men treated at a young age with high dose cranial RT may have impaired fertility. These results suggest that further investigation of men with these treatments is needed to confirm and extend these findings...
- Fertility in women treated with cranial radiotherapy for childhood acute lymphoblastic leukemiaJulianne Byrne
Department of Hematology Oncology, Children s National Medical Center, Washington, DC 20010, USA
Pediatr Blood Cancer 42:589-97. 2004..Although leukemia is the most common cancer of childhood, until now fertility in survivors has not been comprehensively assessed...