M P Fay
Affiliation: National Institutes of Health
- Age-conditional probabilities of developing cancerMichael P Fay
National Cancer Institute, 6116 Executive Blvd, Suite 504, MSC 8317, Bethesda, Maryland 20892 8317, USA
Stat Med 22:1837-48. 2003..this paper provides a comprehensive theoretical basis for estimation and inference about the age-conditional probability of developing a disease...
- Small-sample adjustments for Wald-type tests using sandwich estimatorsM P Fay
National Cancer Institute, Bethesda, Maryland 20892 8317, USA
Biometrics 57:1198-206. 2001....
- Meta-analyses of dietary fats and mammary neoplasms in rodent experimentsM P Fay
Biometry Branch, National Cancer Institute, Bethesda, MD 20892 7354, USA
Breast Cancer Res Treat 46:215-23. 1997..Further, the analysis shows that energy restriction protects against mammary tumors. We show that these results agree qualitatively with estimates of effects on human breast cancer derived from international correlations...
- Comparing several score tests for interval censored dataM P Fay
National Cancer Institute, Bethesda, Maryland 20892 7354, USA
Stat Med 18:273-85. 1999..In contrast, the proportional odds model (Fay's model with logistic error) gives more weight to early differences...
- Conditional logistic regression with sandwich estimators: application to a meta-analysisM P Fay
Biometry Branch, National Cancer Institute, Bethesda, Maryland 20892 7354, USA
Biometrics 54:195-208. 1998..We achieve simulated nominal coverage for these sandwich estimators even when some parameters are estimated from a small number of clusters...
- Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosingAmy D Klion
Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health NIH, Bethesda, MD 20892, USA
Blood 110:3552-6. 2007..This trial was registered at http://www.clinicaltrials.gov as no. NCT00044304...
- Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult MaliansAlassane Dicko
Malaria Research and Training Center, Department of Hematology, University of Bamako, Bamako, Mali
PLoS ONE 2:e1045. 2007..After a peak 14 days following the second vaccination, antibody levels decreased to baseline levels one year later at the time of the third vaccination that induced little or no increase in antibody levels...
- Monitoring rare serious adverse events from a new treatment and testing for a difference from historical controlsMichael P Fay
Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, 6700B Rockledge Drive, Bethesda, MD 20892 7609, USA
Clin Trials 4:598-610. 2007..Controlled but small clinical trials have not detected any increase in the SAE using albendazole, and it is known to have added benefits; therefore, it is unethical to randomize patients to the old regimen...
- Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian childrenAlassane Dicko
Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, Bamako, Mali
PLoS ONE 3:e1563. 2008..The aim of this study was to assess the safety and immunogenicity of this vaccine in young children in a malaria endemic area...
- Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytesGodfrey Lisk
Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland 20892, USA
Antimicrob Agents Chemother 52:2346-54. 2008..Drug development based on such compounds should proceed cautiously in light of possible resistance development though the selection of PSAC mutants...
- Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51Yimin Wu
Malaria Vaccine Development Branch, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, United States of America
PLoS ONE 3:e2636. 2008..This single blinded, dose escalating, controlled Phase 1 study assessed the safety and immunogenicity of recombinant Pfs25 and Pvs25 formulated with Montanide ISA 51, a water-in-oil emulsion...
- Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responsesJeffrey A Lyon
Division Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
PLoS ONE 3:e2830. 2008..Development of an effective MSP1(42) vaccine against erythrocytic stage P. falciparum infection will depend not only on antigen quality, but also upon the selection of an optimal adjuvant component...
- Accounting for variability in sample size estimation with applications to nonadherence and estimation of variance and effect sizeMichael P Fay
National Institute of Allergy and Infectious Diseases, 6700 B Rockledge Drive, Bethesda, Maryland 20892 7609, USA
Biometrics 63:465-74. 2007..This latter situation, as well as several of the previous ones, is motivated by sample size calculations for a Phase II trial of a malaria vaccine candidate...
- KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entitiesIrina Maric
Department of Laboratory Medicine, Clinical Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
J Allergy Clin Immunol 120:680-7. 2007..It is of paramount importance, however, to distinguish between these 2 groups of patients because of differences in clinical sequelae, prognoses, and selection of treatment...
- Estimating average annual percent change for disease rates without assuming constant changeMichael P Fay
National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA
Biometrics 62:847-54. 2006..For the adaptive estimator, we show through simulation that the bootstrap confidence intervals give appropriate coverage...
- Costs of treatment for elderly women with early-stage breast cancer in fee-for-service settingsJoan L Warren
Applied Research Program, National Cancer Institute, Executive Plaza North, Rm 4005, 6130 Executive Blvd, Bethesda, MD 20892 7344, USA
J Clin Oncol 20:307-16. 2002....
- Impact of reporting delay and reporting error on cancer incidence rates and trendsLimin X Clegg
Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 94:1537-45. 2002..We studied the impact of reporting delay and reporting error on incidence rates and trends for cancers of the female breast, colorectal, lung/bronchus, prostate, and melanoma...
- Trends in drinking among Americans age 18 and younger: 1975-2002Vivian B Faden
Division of Epidemiology and Prevention Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892 9304, USA
Alcohol Clin Exp Res 28:1388-95. 2004..In this study, we applied joinpoint statistical methodology to three national data sets to analyze trends in drinking by youth, age 18 and under, for the period 1975 to 2002...
- Comparability of segmented line regression modelsHyune Ju Kim
Department of Mathematics, Syracuse University, Syracuse, New York 13244 1150, USA
Biometrics 60:1005-14. 2004..The tests are applied to compare female lung cancer mortality rates between two registry areas and also to compare female breast cancer mortality rates between two states...
- Random marginal agreement coefficients: rethinking the adjustment for chance when measuring agreementMichael P Fay
National Institute of Allergy and Infectious Diseases, 6700B Rockledge Dr MSC 7609, Bethesda, MD 20892 7609, USA
Biostatistics 6:171-80. 2005..We describe the RMAC for nominal, ordinal and continuous data, and show through the delta method how to approximate the variances of some important special cases...
- Modeling the dissemination of mammography in the United StatesKathleen A Cronin
Statistical Research and Applications Branch, Division of Cancer Control and Population Sciences, Applied Research Branch, National Cancer Institute NIH, MSC 8317, Suite 504, 6116 Executive Boulevard, Bethesda, MD 20892 7359, USA
Cancer Causes Control 16:701-12. 2005..This paper presents a methodology for piecing together disparate data sources to obtain a comprehensive model for the use of mammography screening in the US population for the years 1975-2000...
- Weight change and the risk of late-onset breast cancer in the original Framingham cohortKathy L Radimer
Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
Nutr Cancer 49:7-13. 2004..This study assesses the relation of adult weight change overall and at specific, hormonally relevant times with diagnosis of a first breast cancer after age 55 (late onset)...
- Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand fliesNicola Kimblin
Laboratories of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 105:10125-30. 2008..The low dose resulted in only minor pathology but a higher parasite titer in the chronic phase, and it established the host as an efficient long-term reservoir of infection back to vector sand flies...
- In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand fliesNathan C Peters
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
Science 321:970-4. 2008..Thus, L.m. appears to have evolved to both evade and exploit the innate host response to sand fly bite in order to establish and promote disease...