P Farci

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint New insights into the HCV quasispecies and compartmentalization
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Semin Liver Dis 31:356-74. 2011
  2. pmc Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling
    Oriel Nissim
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e49611. 2012
  3. doi request reprint Clinical features of hepatitis D
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Semin Liver Dis 32:228-36. 2012
  4. pmc Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:14562-7. 2012
  5. pmc B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure
    Patrizia Farci
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:8766-71. 2010
  6. ncbi request reprint Treatment of chronic hepatitis D
    P Farci
    Department of Medical Sciences, University of Cagliari, Policlinico Universitario, Monserrato, Cagliari, Italy
    J Viral Hepat 14:58-63. 2007
  7. ncbi request reprint Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee
    P Farci
    Department of Internal Medicine, University of Cagliari, 09124 Cagliari, Italy
    J Infect Dis 179:1007-11. 1999
  8. ncbi request reprint T lymphocyte subsets and viral infections in Sardinian parenteral drug abusers: relationship to HIV infection
    P Farci
    Department of Internal Medicine, University of Cagliari, Italy
    J Med Virol 27:81-6. 1989
  9. ncbi request reprint The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
    P Farci
    Department of Medical Sciences, University of Cagliari, Via San Giorgio 12, 09124 Cagliari, Italy
    Science 288:339-44. 2000
  10. ncbi request reprint Clinical significance of hepatitis C virus genotypes and quasispecies
    P Farci
    Department of Medical Sciences, University of Cagliari, Italy
    Semin Liver Dis 20:103-26. 2000

Detail Information

Publications11

  1. doi request reprint New insights into the HCV quasispecies and compartmentalization
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Semin Liver Dis 31:356-74. 2011
    ..This review discusses the molecular mechanisms of HCV genetic variation and the biologic and clinical relevance of the quasispecies nature of HCV...
  2. pmc Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling
    Oriel Nissim
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e49611. 2012
    ..We investigated the molecular mechanisms of liver regeneration in 4 patients who underwent liver transplantation for hepatitis B virus (HBV)-associated ALF...
  3. doi request reprint Clinical features of hepatitis D
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Semin Liver Dis 32:228-36. 2012
    ..Hepatitis D is not a vanishing disease, and continuous efforts should be made to improve its prevention and treatment...
  4. pmc Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis
    Patrizia Farci
    Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:14562-7. 2012
    ....
  5. pmc B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure
    Patrizia Farci
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:8766-71. 2010
    ..These data suggest that humoral immunity may exert a primary role in the pathogenesis of HBV-associated ALF...
  6. ncbi request reprint Treatment of chronic hepatitis D
    P Farci
    Department of Medical Sciences, University of Cagliari, Policlinico Universitario, Monserrato, Cagliari, Italy
    J Viral Hepat 14:58-63. 2007
    ....
  7. ncbi request reprint Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee
    P Farci
    Department of Internal Medicine, University of Cagliari, 09124 Cagliari, Italy
    J Infect Dis 179:1007-11. 1999
    ....
  8. ncbi request reprint T lymphocyte subsets and viral infections in Sardinian parenteral drug abusers: relationship to HIV infection
    P Farci
    Department of Internal Medicine, University of Cagliari, Italy
    J Med Virol 27:81-6. 1989
    ..Our data confirm that HIV infection is the major cause of low T helper cells and reversed T helper/suppressor ratio in parenteral drug abusers.(ABSTRACT TRUNCATED AT 250 WORDS)..
  9. ncbi request reprint The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
    P Farci
    Department of Medical Sciences, University of Cagliari, Via San Giorgio 12, 09124 Cagliari, Italy
    Science 288:339-44. 2000
    ..These data indicate that the evolutionary dynamics of the HCV quasispecies during the acute phase of hepatitis C predict whether the infection will resolve or become chronic...
  10. ncbi request reprint Clinical significance of hepatitis C virus genotypes and quasispecies
    P Farci
    Department of Medical Sciences, University of Cagliari, Italy
    Semin Liver Dis 20:103-26. 2000
    ..This article reviews the state of the art on the biologic and clinical implications of the genetic variability of HCV...
  11. ncbi request reprint Hepatitis C virus. The importance of viral heterogeneity
    P Farci
    Department of Medical Sciences, University of Cagliari, Cagliari, Italy
    Clin Liver Dis 5:895-916. 2001
    ..Until such studies are performed, most ideas of viral clearance mechanisms remain hypothetical, and the immunologic basis of HCV clearance will continue to be inferred from associations rather than from causal relationships...