Flavia M Facio

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Motivators for participation in a whole-genome sequencing study: implications for translational genomics research
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Eur J Hum Genet 19:1213-7. 2011
  2. pmc Validation of My Family Health Portrait for six common heritable conditions
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genet Med 12:370-5. 2010
  3. pmc Intentions to receive individual results from whole-genome sequencing among participants in the ClinSeq study
    Flavia M Facio
    Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Eur J Hum Genet 21:261-5. 2013
  4. pmc Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes
    Jennifer J Johnston
    Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Hum Genet 91:97-108. 2012
  5. pmc Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    BMC Med Genomics 5:45. 2012
  6. pmc The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine
    Leslie G Biesecker
    National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 19:1665-74. 2009
  7. pmc FOS expression in blood as a LDL-independent marker of statin treatment
    Ju Gyeong Kang
    Translational Medicine Branch, Cardiology Section National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Atherosclerosis 212:567-70. 2010

Collaborators

Detail Information

Publications7

  1. pmc Motivators for participation in a whole-genome sequencing study: implications for translational genomics research
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Eur J Hum Genet 19:1213-7. 2011
    ....
  2. pmc Validation of My Family Health Portrait for six common heritable conditions
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genet Med 12:370-5. 2010
    ..To assess the ability of My Family Health Portrait to accurately collect family history for six common heritable disorders...
  3. pmc Intentions to receive individual results from whole-genome sequencing among participants in the ClinSeq study
    Flavia M Facio
    Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Eur J Hum Genet 21:261-5. 2013
    ..It behooves investigators to facilitate participants' desire to learn a range of information from genomic sequencing while promoting realistic expectations for its clinical and personal utility...
  4. pmc Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes
    Jennifer J Johnston
    Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Hum Genet 91:97-108. 2012
    ....
  5. pmc Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research
    Flavia M Facio
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    BMC Med Genomics 5:45. 2012
    ..Massively-parallel sequencing (MPS) technologies create challenges for informed consent of research participants given the enormous scale of the data and the wide range of potential results...
  6. pmc The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine
    Leslie G Biesecker
    National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genome Res 19:1665-74. 2009
    ..The early experiences with ClinSeq illustrate how large-scale medical sequencing can be a practical, productive, and critical component of research in genomic medicine...
  7. pmc FOS expression in blood as a LDL-independent marker of statin treatment
    Ju Gyeong Kang
    Translational Medicine Branch, Cardiology Section National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Atherosclerosis 212:567-70. 2010
    ..In this pilot study, we hypothesized that blood FOS mRNA levels will be sensitive to statin treatment independent of LDL cholesterol levels...