Leonard H Evans

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Analysis of two monoclonal antibodies reactive with envelope proteins of murine retroviruses: One pan specific antibody and one specific for Moloney leukemia virus
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, United States Electronic address
    J Virol Methods 200:47-53. 2014
  2. pmc Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line
    Janet W Hartley
    Laboratory of Immunopathology, NIAID, NIH, Bethesda, MD 20892, USA
    Retrovirology 5:1. 2008
  3. pmc Antigenic subclasses of polytropic murine leukemia virus (MLV) isolates reflect three distinct groups of endogenous polytropic MLV-related sequences in NFS/N mice
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA
    J Virol 77:10327-38. 2003
  4. pmc Mobilization of endogenous retroviruses in mice after infection with an exogenous retrovirus
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 83:2429-35. 2009
  5. pmc In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infections
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 80:4748-57. 2006
  6. pmc Suppression of acute anti-friend virus CD8+ T-cell responses by coinfection with lactate dehydrogenase-elevating virus
    Shelly J Robertson
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    J Virol 82:408-18. 2008
  7. pmc Precise identification of endogenous proviruses of NFS/N mice participating in recombination with moloney ecotropic murine leukemia virus (MuLV) to generate polytropic MuLVs
    A S M Alamgir
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, 903 S 4th St, Hamilton, MT 59840, USA
    J Virol 79:4664-71. 2005
  8. pmc Profound amplification of pathogenic murine polytropic retrovirus release from coinfected cells
    Kyle Rosenke
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA
    J Virol 86:7241-8. 2012
  9. pmc The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3
    Angelo Kolokithas
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 84:10933-6. 2010
  10. pmc Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice
    Ingunn M Stromnes
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases NIH, Hamilton, Montana 59840, USA
    J Virol 76:2225-32. 2002

Collaborators

  • Karin E Peterson
  • K J Hasenkrug
  • Bruce Chesebro
  • Brent Race
  • Janet W Hartley
  • K Y Green
  • Ulf Dittmer
  • Jerrold M Ward
  • W A Cafruny
  • Kyle Rosenke
  • Angelo Kolokithas
  • Frank Malik
  • Duncan Hendrick
  • Marc Lavignon
  • Shelly J Robertson
  • Lucie Baudino
  • A S M Alamgir
  • Ronald J Messer
  • Ingunn M Stromnes
  • Kimmo Virtaneva
  • Lukas Swanson
  • John L Portis
  • Mario L Santiago
  • Nicole Gerlach
  • Lara Myers
  • Christoph G Ammann
  • Shuichi Kikuchi
  • Naoki Morito
  • Rebecca M Tucker
  • Kumiko Yoshinobu
  • Shozo Izui
  • Bernard J Morley
  • Liliane Fossati-Jimack
  • Timothy J Vyse
  • Christina L Roark
  • Sachiko Hirose
  • Brian L Kotzin
  • Aaron B Carmody
  • Savita Nair
  • Trine N Jørgensen
  • Nick Owens
  • Koen Schepers
  • Ton N M Schumacher

Detail Information

Publications13

  1. doi request reprint Analysis of two monoclonal antibodies reactive with envelope proteins of murine retroviruses: One pan specific antibody and one specific for Moloney leukemia virus
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, United States Electronic address
    J Virol Methods 200:47-53. 2014
    ..The derivation of these antibodies as well as their characterization with regard to their isotype, range of reactivity with different MuLVs and utility in different immunological procedures are described in this study. ..
  2. pmc Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line
    Janet W Hartley
    Laboratory of Immunopathology, NIAID, NIH, Bethesda, MD 20892, USA
    Retrovirology 5:1. 2008
    ....
  3. pmc Antigenic subclasses of polytropic murine leukemia virus (MLV) isolates reflect three distinct groups of endogenous polytropic MLV-related sequences in NFS/N mice
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA
    J Virol 77:10327-38. 2003
    ....
  4. pmc Mobilization of endogenous retroviruses in mice after infection with an exogenous retrovirus
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 83:2429-35. 2009
    ....
  5. pmc In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infections
    Leonard H Evans
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 80:4748-57. 2006
    ..This study illustrates the complexity of the interactions between components of mixed retrovirus infections and the dramatic effects of these interactions on disease processes...
  6. pmc Suppression of acute anti-friend virus CD8+ T-cell responses by coinfection with lactate dehydrogenase-elevating virus
    Shelly J Robertson
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    J Virol 82:408-18. 2008
    ..Coinfection of mice with LDV and FV provides a well-defined, natural host model for such studies...
  7. pmc Precise identification of endogenous proviruses of NFS/N mice participating in recombination with moloney ecotropic murine leukemia virus (MuLV) to generate polytropic MuLVs
    A S M Alamgir
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, 903 S 4th St, Hamilton, MT 59840, USA
    J Virol 79:4664-71. 2005
    ..These observations suggest a possible mechanism for the specificity of recombination observed for different ecotropic MuLVs...
  8. pmc Profound amplification of pathogenic murine polytropic retrovirus release from coinfected cells
    Kyle Rosenke
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA
    J Virol 86:7241-8. 2012
    ..Mixed infections are the rule rather than the exception in retroviral infection, and the ability to examine them in vitro should facilitate a more thorough understanding of retroviral interactions in general...
  9. pmc The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3
    Angelo Kolokithas
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 84:10933-6. 2010
    ..Furthermore, a gGag-deficient virus restricted for replication in wild-type mice replicates efficiently in APOBEC3 knockout mice, implying a novel role of gGag in circumventing the action of APOBEC3 in vivo...
  10. pmc Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice
    Ingunn M Stromnes
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases NIH, Hamilton, Montana 59840, USA
    J Virol 76:2225-32. 2002
    ..Eventually, all of the IFN-gamma-deficient mice failed to keep persistent virus in check and developed fatal FV-induced erythroleukemia...
  11. ncbi request reprint Increased proinflammatory cytokine and chemokine responses and microglial infection following inoculation with neural stem cells infected with polytropic murine retroviruses
    Karin E Peterson
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr, Baton Rouge, LA 70803, USA
    Virology 354:143-53. 2006
    ..As polytropic and ecotropic viruses utilize different receptors for entry, these receptors may play a critical role in the induction of these innate immune responses in the brain...
  12. pmc Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritis
    Lucie Baudino
    Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
    J Immunol 181:2846-54. 2008
    ..Our data indicate that the genetic origin of serum gp70 is more heterogeneous than previously thought, and that distinct retroviral gp70s are differentially regulated in physiological vs inflammatory conditions...
  13. ncbi request reprint Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection
    Ulf Dittmer
    Institut für Virologie des Universitätsklinikums, 45122 Essen, Germany
    Immunity 20:293-303. 2004
    ..The results indicate that CD4(+) regulatory T cells contribute to viral persistence and demonstrate an immunotherapy for treating chronic retroviral infections...