Research Topics
Species | Leonard H EvansSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell lineJanet W Hartley
Laboratory of Immunopathology, NIAID, NIH, Bethesda, MD 20892, USA
Retrovirology 5:1. 2008....
Antigenic subclasses of polytropic murine leukemia virus (MLV) isolates reflect three distinct groups of endogenous polytropic MLV-related sequences in NFS/N miceLeonard H Evans
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA
J Virol 77:10327-38. 2003....
Mobilization of endogenous retroviruses in mice after infection with an exogenous retrovirusLeonard H Evans
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
J Virol 83:2429-35. 2009....
In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infectionsLeonard H Evans
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
J Virol 80:4748-57. 2006..This study illustrates the complexity of the interactions between components of mixed retrovirus infections and the dramatic effects of these interactions on disease processes...
Suppression of acute anti-friend virus CD8+ T-cell responses by coinfection with lactate dehydrogenase-elevating virusShelly J Robertson
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
J Virol 82:408-18. 2008..Coinfection of mice with LDV and FV provides a well-defined, natural host model for such studies...
Precise identification of endogenous proviruses of NFS/N mice participating in recombination with moloney ecotropic murine leukemia virus (MuLV) to generate polytropic MuLVsA S M Alamgir
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, 903 S. 4th St, Hamilton, MT 59840, USA
J Virol 79:4664-71. 2005..These observations suggest a possible mechanism for the specificity of recombination observed for different ecotropic MuLVs...
Profound amplification of pathogenic murine polytropic retrovirus release from coinfected cellsKyle Rosenke
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA
J Virol 86:7241-8. 2012..Mixed infections are the rule rather than the exception in retroviral infection, and the ability to examine them in vitro should facilitate a more thorough understanding of retroviral interactions in general...
The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3Angelo Kolokithas
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
J Virol 84:10933-6. 2010..Furthermore, a gGag-deficient virus restricted for replication in wild-type mice replicates efficiently in APOBEC3 knockout mice, implying a novel role of gGag in circumventing the action of APOBEC3 in vivo...
Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in miceIngunn M Stromnes
Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases/NIH, Hamilton, Montana 59840, USA
J Virol 76:2225-32. 2002..Eventually, all of the IFN-gamma-deficient mice failed to keep persistent virus in check and developed fatal FV-induced erythroleukemia...
Increased proinflammatory cytokine and chemokine responses and microglial infection following inoculation with neural stem cells infected with polytropic murine retrovirusesKarin E Peterson
Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Dr, Baton Rouge, LA 70803, USA
Virology 354:143-53. 2006..As polytropic and ecotropic viruses utilize different receptors for entry, these receptors may play a critical role in the induction of these innate immune responses in the brain...
Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritisLucie Baudino
Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
J Immunol 181:2846-54. 2008..Our data indicate that the genetic origin of serum gp70 is more heterogeneous than previously thought, and that distinct retroviral gp70s are differentially regulated in physiological vs inflammatory conditions...
Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infectionUlf Dittmer
, 45122 Essen, Germany
Immunity 20:293-303. 2004..The results indicate that CD4(+) regulatory T cells contribute to viral persistence and demonstrate an immunotherapy for treating chronic retroviral infections...
