Jacob D Estes

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche
    Jacob D Estes
    AIDS and Cancer Virus Program, Science Applications International Corporation Frederick, Inc, National Cancer Institute, Frederick, MD, USA
    Semin Immunol 20:181-6. 2008
  2. ncbi request reprint Role of collagen deposition in lymphatic tissues and immune reconstruction during HIV-1 and SIV infections
    Jacob D Estes
    The AIDS and Cancer Virus Program, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Fort Detrick Campus, Frederick, MD 21702, USA
    Curr HIV/AIDS Rep 6:29-35. 2009
  3. doi request reprint Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA
    Immunol Rev 254:65-77. 2013
  4. pmc Enhancing immune responses to limit chronic immune activation during SIV
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick Inc, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA
    J Clin Invest 122:1611-4. 2012
  5. pmc Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland, USA
    PLoS Pathog 6:e1001052. 2010
  6. pmc Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection
    Brian Tabb
    AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, SAIC Frederick, Maryland, USA
    J Infect Dis 207:880-92. 2013
  7. pmc Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
    Levelle D Harris
    Laboratory of Molecular Microbiology, NIAID, NIH, Bethesda, Maryland, USA
    J Virol 84:7886-91. 2010
  8. pmc Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection
    Jacob T Minang
    AIDS and Cancer Virus Program, SAIC Frederick, Frederick, MD 21702, USA
    J Immunol 184:315-26. 2010
  9. pmc Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques
    Nichole R Klatt
    National Institute of Allergy and Infectious Diseases NIAID, NIH, Bethesda, Maryland, USA
    J Clin Invest 123:903-7. 2013
  10. pmc Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission
    Jeremy Smedley
    Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc, Frederick National Laboratory, Frederick, Maryland, United States of America
    PLoS ONE 9:e92830. 2014

Collaborators

Detail Information

Publications13

  1. pmc The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche
    Jacob D Estes
    AIDS and Cancer Virus Program, Science Applications International Corporation Frederick, Inc, National Cancer Institute, Frederick, MD, USA
    Semin Immunol 20:181-6. 2008
    ....
  2. ncbi request reprint Role of collagen deposition in lymphatic tissues and immune reconstruction during HIV-1 and SIV infections
    Jacob D Estes
    The AIDS and Cancer Virus Program, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Fort Detrick Campus, Frederick, MD 21702, USA
    Curr HIV/AIDS Rep 6:29-35. 2009
    ....
  3. doi request reprint Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA
    Immunol Rev 254:65-77. 2013
    ....
  4. pmc Enhancing immune responses to limit chronic immune activation during SIV
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick Inc, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA
    J Clin Invest 122:1611-4. 2012
    ....
  5. pmc Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
    Jacob D Estes
    AIDS and Cancer Virus Program, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland, USA
    PLoS Pathog 6:e1001052. 2010
    ..Novel therapeutic approaches to inhibit microbial translocation and/or attenuate chronic immune activation in HIV-infected individuals may complement treatments aimed at direct suppression of viral replication...
  6. pmc Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection
    Brian Tabb
    AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, SAIC Frederick, Maryland, USA
    J Infect Dis 207:880-92. 2013
    ....
  7. pmc Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
    Levelle D Harris
    Laboratory of Molecular Microbiology, NIAID, NIH, Bethesda, Maryland, USA
    J Virol 84:7886-91. 2010
    ..In contrast, persistently high type I IFN responses are observed during pathogenic SIV infection of rhesus macaques...
  8. pmc Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection
    Jacob T Minang
    AIDS and Cancer Virus Program, SAIC Frederick, Frederick, MD 21702, USA
    J Immunol 184:315-26. 2010
    ....
  9. pmc Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques
    Nichole R Klatt
    National Institute of Allergy and Infectious Diseases NIAID, NIH, Bethesda, Maryland, USA
    J Clin Invest 123:903-7. 2013
    ..Thus, ARV synbiotic supplementation in HIV-infected individuals may improve GI tract immunity and thereby mitigate inflammatory sequelae, ultimately improving prognosis...
  10. pmc Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission
    Jeremy Smedley
    Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc, Frederick National Laboratory, Frederick, Maryland, United States of America
    PLoS ONE 9:e92830. 2014
    ..These results provide insights into potential patterns of viral dissemination that can help guide efforts to better elucidate the earliest events of virus transmission and potential intervention strategies...
  11. ncbi request reprint Molecularly Tagged Simian Immunodeficiency Virus SIVmac239 Synthetic Swarm for Tracking Independent Infection Events
    Gregory Q Del Prete
    AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA
    J Virol 88:8077-90. 2014
    ..This approach should be useful for tracking individual infection events in preclinical vaccine evaluations, long-term viral reservoir establishment/clearance research, and transmission/early-event studies...
  12. pmc Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques
    Gregory Q Del Prete
    AIDS and Cancer Virus Program, National Cancer Institute, Frederick, Maryland, USA
    J Virol 86:3152-66. 2012
    ..Given that human APOBEC proteins restrict XMRV infection in vitro, human XMRV infection, if it occurred, would be expected to be characterized by similarly limited viral replication and spread...
  13. pmc Barriers to mucosal transmission of immunodeficiency viruses
    Brandon F Keele
    AIDS and Cancer Virus Program, SAIC Frederick Inc, National Cancer Institute, Frederick, MD, USA
    Blood 118:839-46. 2011
    ..Understanding the initial events of infection, before systemic spread, could provide insights into strategies for reducing acquisition or ameliorating clinical outcome...