K M Druey

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Bridging with GAPs: receptor communication through RGS proteins
    K M Druey
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases NIH, Rockville, MD 20852, USA
    Sci STKE 2001:re14. 2001
  2. ncbi Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling
    K M Druey
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20852, USA
    J Biol Chem 274:18836-42. 1999
  3. ncbi RGS16 function is regulated by epidermal growth factor receptor-mediated tyrosine phosphorylation
    A Derrien
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
    J Biol Chem 276:48532-8. 2001

Collaborators

  • A Derrien

Detail Information

Publications3

  1. ncbi Bridging with GAPs: receptor communication through RGS proteins
    K M Druey
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases NIH, Rockville, MD 20852, USA
    Sci STKE 2001:re14. 2001
    ..RGS proteins may also serve as a bridge from GPCRs to receptor tyrosine kinases or transmembrane channels, allowing signals from GPCRs to regulate signaling through other types of receptors, and vice versa...
  2. ncbi Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling
    K M Druey
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20852, USA
    J Biol Chem 274:18836-42. 1999
    ....
  3. ncbi RGS16 function is regulated by epidermal growth factor receptor-mediated tyrosine phosphorylation
    A Derrien
    Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
    J Biol Chem 276:48532-8. 2001
    ..These data suggest that tyrosine phosphorylation regulates RGS16 function and that EGFR may potentially inhibit Galpha(i)-dependent MAPK activation in a feedback loop by enhancing RGS16 activity through tyrosine phosphorylation...