- Bridging with GAPs: receptor communication through RGS proteinsK M Druey
Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases NIH, Rockville, MD 20852, USA
Sci STKE 2001:re14. 2001..RGS proteins may also serve as a bridge from GPCRs to receptor tyrosine kinases or transmembrane channels, allowing signals from GPCRs to regulate signaling through other types of receptors, and vice versa...
- Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signalingK M Druey
Molecular Signal Transduction Section, Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland 20852, USA
J Biol Chem 274:18836-42. 1999....
- RGS16 function is regulated by epidermal growth factor receptor-mediated tyrosine phosphorylationA Derrien
Molecular Signal Transduction Section, Laboratory of Allergic Diseases, National Institutes of Health, Rockville, Maryland 20852, USA
J Biol Chem 276:48532-8. 2001..These data suggest that tyrosine phosphorylation regulates RGS16 function and that EGFR may potentially inhibit Galpha(i)-dependent MAPK activation in a feedback loop by enhancing RGS16 activity through tyrosine phosphorylation...