Lori E Dodd

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Correcting log ratios for signal saturation in cDNA microarrays
    Lori E Dodd
    Biometric Research Branch, DCTD, National Cancer Institute, Bethesda, MD 20892 7434, USA
    Bioinformatics 20:2685-93. 2004
  2. ncbi request reprint Partial AUC estimation and regression
    Lori E Dodd
    Biometric Research Branch, National Cancer Institute, 6130 Executive Blvd, MSC 7434, Rockville, Maryland 20892, USA
    Biometrics 59:614-23. 2003
  3. pmc An audit strategy for progression-free survival
    Lori E Dodd
    Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland 20892, USA
    Biometrics 67:1092-9. 2011
  4. pmc Blinded independent central review of progression-free survival in phase III clinical trials: important design element or unnecessary expense?
    Lori E Dodd
    Division of Cancer Treatment and Diagnosis, Branches of Biometric Research, Investigational Drug, Cancer Investigations, and Diagnostic Imaging, National Cancer Institute, Rockville, MD 20892, USA
    J Clin Oncol 26:3791-6. 2008
  5. ncbi request reprint Lack of generalizability of sensitivity and specificity with treatment effects
    Lori E Dodd
    Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Blvd, Bethesda, MD 20892, U S A
    Stat Med 27:1734-44. 2008
  6. ncbi request reprint Assessment methodologies and statistical issues for computer-aided diagnosis of lung nodules in computed tomography: contemporary research topics relevant to the lung image database consortium
    Lori E Dodd
    Biometrics Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Blvd, MSC 7434, Bethesda, MD 20892, USA
    Acad Radiol 11:462-75. 2004
  7. doi request reprint Measurement error in the timing of events: effect on survival analyses in randomized clinical trials
    Edward L Korn
    Biometric Research Branch, National Cancer Institute, Bethesda, MD 20892, USA
    Clin Trials 7:626-33. 2010
  8. ncbi request reprint An audit strategy for time-to-event outcomes measured with error: application to five randomized controlled trials in oncology
    Lori E Dodd
    aBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
    Clin Trials 10:754-60. 2013
  9. ncbi request reprint Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma
    Lori E Dodd
    National Cancer Institute, 6120 Executive Boulevard, Room 7062, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:2216-25. 2006
  10. doi request reprint Elevations in D-dimer and C-reactive protein are associated with the development of osteonecrosis of the hip in HIV-infected adults
    Caryn G Morse
    Critical Care Medicine Department, NIH Clinical Center, Bethesda, MD, USA
    AIDS 27:591-5. 2013

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Correcting log ratios for signal saturation in cDNA microarrays
    Lori E Dodd
    Biometric Research Branch, DCTD, National Cancer Institute, Bethesda, MD 20892 7434, USA
    Bioinformatics 20:2685-93. 2004
    ..In practice, spots with saturated pixels are discarded or the biased value is used. Neither of these approaches is appealing, particularly the former approach when a highly expressed gene is discarded because of saturation...
  2. ncbi request reprint Partial AUC estimation and regression
    Lori E Dodd
    Biometric Research Branch, National Cancer Institute, 6130 Executive Blvd, MSC 7434, Rockville, Maryland 20892, USA
    Biometrics 59:614-23. 2003
    ..We use the regression framework to compare two prostate-specific antigen biomarkers and to evaluate the dependence of biomarker accuracy on the time prior to clinical diagnosis of prostate cancer...
  3. pmc An audit strategy for progression-free survival
    Lori E Dodd
    Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland 20892, USA
    Biometrics 67:1092-9. 2011
    ..A two-stage auditing strategy is also proposed and evaluated through simulation studies. The method is applied retrospectively to a large oncology trial that had a complete-case BICR, showing the potential for efficiency improvements...
  4. pmc Blinded independent central review of progression-free survival in phase III clinical trials: important design element or unnecessary expense?
    Lori E Dodd
    Division of Cancer Treatment and Diagnosis, Branches of Biometric Research, Investigational Drug, Cancer Investigations, and Diagnostic Imaging, National Cancer Institute, Rockville, MD 20892, USA
    J Clin Oncol 26:3791-6. 2008
    ..When such designs are not practical, BICR is not recommended as a general strategy for reducing bias. However, BICR may be useful as an auditing tool to assess the reliability of marginally positive results...
  5. ncbi request reprint Lack of generalizability of sensitivity and specificity with treatment effects
    Lori E Dodd
    Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Blvd, Bethesda, MD 20892, U S A
    Stat Med 27:1734-44. 2008
    ..These results demonstrate that evaluating sensitivity and specificity within treatment (or other covariate) groups is necessary even when simple proportional hazards models or the Prentice criterion holds...
  6. ncbi request reprint Assessment methodologies and statistical issues for computer-aided diagnosis of lung nodules in computed tomography: contemporary research topics relevant to the lung image database consortium
    Lori E Dodd
    Biometrics Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, 6130 Executive Blvd, MSC 7434, Bethesda, MD 20892, USA
    Acad Radiol 11:462-75. 2004
    ..We review methods for performance assessment and discuss issues of defining "truth" as well as the complications that arise when truth information is not available. We also discuss issues about sizing and populating a database...
  7. doi request reprint Measurement error in the timing of events: effect on survival analyses in randomized clinical trials
    Edward L Korn
    Biometric Research Branch, National Cancer Institute, Bethesda, MD 20892, USA
    Clin Trials 7:626-33. 2010
    ....
  8. ncbi request reprint An audit strategy for time-to-event outcomes measured with error: application to five randomized controlled trials in oncology
    Lori E Dodd
    aBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
    Clin Trials 10:754-60. 2013
    ..Similar BICR and local evaluation HRs may provide reassurance about the treatment effect, but BICR adds considerable time and expense to trials...
  9. ncbi request reprint Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma
    Lori E Dodd
    National Cancer Institute, 6120 Executive Boulevard, Room 7062, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:2216-25. 2006
    ..Our results suggest that nitrosamine activation and DNA repair are important in NPC. The consistent down-regulation of expression on chromosome 14q32 suggests loss of heterozygosity in this region...
  10. doi request reprint Elevations in D-dimer and C-reactive protein are associated with the development of osteonecrosis of the hip in HIV-infected adults
    Caryn G Morse
    Critical Care Medicine Department, NIH Clinical Center, Bethesda, MD, USA
    AIDS 27:591-5. 2013
    ..We investigated the levels of D-dimer and C-reactive protein (CRP) in a cohort of HIV-infected adults with and without osteonecrosis of the femoral head...
  11. ncbi request reprint A cautionary note on the robustness of latent class models for estimating diagnostic error without a gold standard
    Paul S Albert
    Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892, USA
    Biometrics 60:427-35. 2004
    ..Further, data analysis and simulations demonstrate the practical implications of model misspecification. Finally, we present some guidelines about the use of these models for practitioners...
  12. pmc Evaluation of the polyclonal ELISA HPV serology assay as a biomarker for human papillomavirus exposure
    Sarah E Coseo
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Sex Transm Dis 38:976-82. 2011
    ..Overall performance of these assays, as a measure of HPV exposure, has not been evaluated...
  13. ncbi request reprint PSA velocity and prostate cancer
    Lori E Dodd
    N Engl J Med 351:1800-2; author reply 1800-2. 2004