Research Topics
| G E DinseSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Parameterizing dose-response models to estimate relative potency functions directlyGregg E Dinse
Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Toxicol Sci 129:447-55. 2012..S. National Toxicology Program bioassays. Though not universally applicable, this method of estimating relative potency functions directly can be profitably applied to a broad family of dose-response models commonly used in toxicology...
Unexplained increases in cancer incidence in the United States from 1975 to 1994: possible sentinel health indicators?G E Dinse
Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Annu Rev Public Health 20:173-209. 1999..Unexplained patterns of cancer incidence may signal changes in underlying risk factors and highlight the continuing need for research on cancer etiology and prevention...
Characterizing non-constant relative potencyGregg E Dinse
Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 2233, USA
Regul Toxicol Pharmacol 60:342-53. 2011..We illustrate these ideas with constructed examples and real data. Relative potency functions offer a unified and principled description of relative potency for non-similar dose-response curves...
X-ray evidence of increased asbestos exposure in the US population from NHANES I and NHANES II, 1973-1978. National Health Examination SurveyW J Rogan
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Cancer Causes Control 11:441-9. 2000..At least one indicator of asbestos exposure, mesothelioma, has been increasing in the US for decades. We investigated the prevalence of another indicator, pleural thickening on x-ray, in a defined sample of the US population...
Effects of arsenic, cadmium, chromium, and lead on gene expression regulated by a battery of 13 different promoters in recombinant HepG2 cellsD B Tully
Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709, USA
Toxicol Appl Pharmacol 168:79-90. 2000..It is also an important finding that no evidence of synergistic activity was detected with the mixture of Cd(II), Cr(III), and Pb(II) tested in these assays...
Distinguishing effects on tumor multiplicity and growth rate in chemoprevention experimentsD B Dunson
Biostatistics Branch, MD A3 03, National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
Biometrics 56:1068-75. 2000..A Gibbs sampler is developed for estimation of the posterior distributions of the parameters. The methods are illustrated through application to data from a breast cancer chemoprevention experiment...
