Research Topics
| Daniel P DicksteinSummaryAffiliation: National Institutes of Health Country: USA Publications
Research Grants
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Detail Information
Publications
Emotion regulation in children and adolescents: boundaries between normalcy and bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorder Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
Dev Psychopathol 18:1105-31. 2006..Taken as a whole, this work implicates a neural circuit encompassing the prefrontal cortex, amygdala, and striatum in the pathophysiology of pediatric BD...- Comorbid anxiety in phenotypes of pediatric bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorders Program, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
J Child Adolesc Psychopharmacol 15:534-48. 2005..Adult BPD studies suggest comorbid anxiety disorders are common and impact treatment outcome. We explored the association of comorbid anxiety with two phenotypes of pediatric BPD... - Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry studyDaniel P Dickstein
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
Arch Gen Psychiatry 62:734-41. 2005..While numerous magnetic resonance imaging (MRI) studies have evaluated adults with bipolar disorder (BPD), few have examined MRI changes in children with BPD... - Cognitive flexibility in phenotypes of pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 9000 Rockville Pike, MSC 2670 Building 15K Room 204, Bethesda MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 46:341-55. 2007..6 +/- 2.4 years). Cognitive flexibility is relevant to symptoms of BD involving dysfunctional reward systems (e.g., excessive goal-directed activity and pleasure-seeking in mania; anhedonia in depression)... 
Neural activation during encoding of emotional faces in pediatric bipolar disorderDaniel P Dickstein
Division of Intramural Research Program, National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, MD 20892 2670, USA
Bipolar Disord 9:679-92. 2007..To begin to address these limitations, the current study tests the hypothesis that pediatric BD (PBD) subjects exhibit altered neural activation during encoding of emotional faces compared to typically developing controls...- Deficits in social cognition and response flexibility in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, NIMH, 15K North Dr, Room 102, MSC 2670, Bethesda, MD 20892, USA
Am J Psychiatry 162:1644-51. 2005..The purpose of this study was to test the hypothesis that youths with bipolar disorder would perform more poorly than matched healthy comparison subjects on measures of social cognition, motor inhibition, and response flexibility... - Brain systems underlying response flexibility in healthy and bipolar adolescents: an event-related fMRI studyEric E Nelson
Mood and Anxiety Disorders Program, National Institute of Mental Health, Building 106 C, 5413 W Cedar Lane, Bethesda, MD 20892, USA
Bipolar Disord 9:810-9. 2007..The present study was undertaken to determine if neuronal responses differed between BD and control subjects on a simple motor response flexibility task... - Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulationMelissa A Brotman
Emotion and Development Branch and the Genetic Basis of Mood and Anxiety Disorders Unit, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Psychiatry 164:1238-41. 2007..The authors compared axis I diagnoses in parents of children with narrow phenotype bipolar disorder and parents of youth with severe mood dysregulation... - Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorderEllen Leibenluft
Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 164:52-60. 2007..They also compared activation in medicated versus unmedicated children with bipolar disorder and in children with bipolar disorder and attention deficit hyperactivity disorder (ADHD) versus those with bipolar disorder without ADHD... - Neural connectivity in children with bipolar disorder: impairment in the face emotion processing circuitBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda 20892 2670, MD, USA
J Child Psychol Psychiatry 49:88-96. 2008.... - Facial emotion labeling deficits in children and adolescents at risk for bipolar disorderMelissa A Brotman
Mood and Anxiety Disorders Program, NIMH, NIH, Bethesda, MD 20892, USA
Am J Psychiatry 165:385-9. 2008.... - Proton magnetic resonance spectroscopy in youth with severe mood dysregulationDaniel P Dickstein
Unit on Bipolar Spectrum Disorders, Division of Intramural Research Programs, National Institute of Mental Health, Bethesda, MD, USA
Psychiatry Res 163:30-9. 2008.... - Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disordersMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Biol Psychiatry 61:819-21. 2007..Although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness... - Memory and learning in pediatric bipolar disorderErin B McClure
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 44:461-9. 2005..To test the hypothesis that patients with pediatric bipolar disorder (PBPD) would demonstrate impairment relative to diagnosis-free controls of comparable age, gender, and IQ on measures of memory functioning... - Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in childrenMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Biol Psychiatry 60:991-7. 2006..This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). This study examines prevalence, concurrent Axis I diagnoses, and longitudinal outcome of SMD in an epidemiologic sample... - Neuropsychological performance in pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health Mood and Anxiety Disorders Program, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-1255, USA
Biol Psychiatry 55:32-9. 2004..Our work suggests altered ventrolateral prefrontal cortex function, especially when linked to other lesion and neuroimaging studies... - Altered neural function in pediatric bipolar disorder during reversal learningDaniel P Dickstein
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
Bipolar Disord 12:707-19. 2010..Here, we use event-related functional magnetic resonance imaging (fMRI) to elucidate neural correlates of reversal learning deficits in euthymic BD youth compared to typically developing controls... - Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
Biol Psychiatry 58:517-24. 2005..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children... - Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorderTristan Gorrindo
Mood and Anxiety Program, National Institute of Mental Health, Bldg. 10, Rm. 4N-208, 10 Center Dr.-MSC 1255, Bethesda, MD 20892-1255, USA
Am J Psychiatry 162:1975-7. 2005..CONCLUSIONS: Children with bipolar disorder may have a reversal learning deficit... - Using affect-modulated startle to study phenotypes of pediatric bipolar disorderBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892, USA
Bipolar Disord 7:536-45. 2005..The current study used affect-modulated startle to examine potential differences in reactivity to emotional stimuli (reward and punishment) in narrow and broad phenotype PBD and controls... - Cross-sectional and longitudinal abnormalities in brain structure in children with severe mood dysregulation or bipolar disorderNancy E Adleman
Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA Bradley Hospital Warren Alpert Medical School, Brown University, Providence, RI, USA
J Child Psychol Psychiatry 53:1149-56. 2012..Because of the high proportion of co-occurring ADHD in the SMD subjects, we could not separate effects of ADHD from those of SMD, and future research including a nonirritable ADHD group must address this issue... - Reward-related processes in pediatric bipolar disorder: a pilot studyMonique Ernst
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K North Drive, Room 118, Bethesda, MD 20892 2670, USA
J Affect Disord 82:S89-S101. 2004..We hypothesized that relative to healthy children, children with BPD would select risky options more frequently, be less confident in a favorable outcome, and report stronger emotional responses to outcomes... - Selective reduction in amygdala volume in pediatric anxiety disorders: a voxel-based morphometry investigationMichael P Milham
Beckman Institute, University of Illinois, Urbana, Illinois, USA
Biol Psychiatry 57:961-6. 2005..We examine the neural correlates of pediatric anxiety disorders, to consider the validity of the categorization scheme used in recent treatment studies... - Anxiety and labile hypertension in a 16-year-old male: the value of biopsychosocial medicineMartin T Stein
University of California San Diego, San Diego, California, USA
J Dev Behav Pediatr 24:301-5. 2003
Research Grants
- Reversal Learning in Pediatric Bipolar DisorderDANIEL DICKSTEIN; Fiscal Year: 2007....