Bryan D Devan

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 183:439-45. 2006
  2. ncbi request reprint Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD, 21224, USA
    Pharmacol Biochem Behav 79:691-9. 2004
  3. ncbi request reprint Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitro-L-arginine methyl ester
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, 5600 Nathan Shock Dr, Baltimore MD 21204, United States
    Eur J Pharmacol 563:134-40. 2007
  4. ncbi request reprint Combined administration of subthreshold doses of the nitric oxide inhibitor, nitro-L-arginine, and muscarinic receptor antagonist, scopolamine, impairs complex maze learning in rats
    Paul J Pistell
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, Baltimore, Maryland, USA
    Behav Pharmacol 18:801-5. 2007
  5. ncbi request reprint A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats
    Kara B Duffy
    Laboratory of Experimental Gerontology, Intramural Research Program, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Neurobiol Aging 29:1680-9. 2008
  6. pmc Striatal lesions interfere with acquisition of a complex maze task in rats
    Paul J Pistell
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
    Behav Brain Res 197:138-43. 2009
  7. doi request reprint Phosphodiesterase inhibition facilitates cognitive restoration in rodent models of age-related memory decline
    Bryan D Devan
    Laboratory of Comparative Neuropsychology, Psychology Department, Towson University, Towson, MD, USA Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, Baltimore, MD, USA
    NeuroRehabilitation 34:101-11. 2014
  8. ncbi request reprint The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats
    Anne M Janas
    Laboratory of Experimental Gerontology, NIA NIH, Gerontology Research Center, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Life Sci 76:1073-81. 2005
  9. ncbi request reprint The challenges of understanding mammalian cognition and memory-based behaviours: an interactive learning and memory systems approach
    Robert J McDonald
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alta, Canada AB T1K 3M4
    Neurosci Biobehav Rev 28:719-45. 2004
  10. ncbi request reprint Effect of D-serine on a delayed match-to-place task for the water maze
    Eric M Stouffer
    Department of Psychology, Laboratory of Comparative Neuropsychology, Towson University, Towson, MD 21252 0001, USA
    Behav Brain Res 152:447-52. 2004

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 183:439-45. 2006
    ..Recent findings suggest that inhibition of phosphodiesterase (PDE) enzymes that degrade cGMP may have memory-enhancing effects...
  2. ncbi request reprint Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD, 21224, USA
    Pharmacol Biochem Behav 79:691-9. 2004
    ..These results suggest that sildenafil citrate may serve as a cognitive enhancer for therapeutic treatment of cholinergic dysfunction in age-related cognitive decline and Alzheimer's dementia (AD)...
  3. ncbi request reprint Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitro-L-arginine methyl ester
    Bryan D Devan
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, 5600 Nathan Shock Dr, Baltimore MD 21204, United States
    Eur J Pharmacol 563:134-40. 2007
    ..This pathway has been implicated in age-related cognitive decline and may be a useful target for pharmacological intervention of neurodegenerative disease...
  4. ncbi request reprint Combined administration of subthreshold doses of the nitric oxide inhibitor, nitro-L-arginine, and muscarinic receptor antagonist, scopolamine, impairs complex maze learning in rats
    Paul J Pistell
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, Baltimore, Maryland, USA
    Behav Pharmacol 18:801-5. 2007
    ..These data suggest that manipulation of learning and memory processes with multiple compounds potentially offers a clinically relevant paradigm for investigating cognitive function in normal and abnormal aging...
  5. ncbi request reprint A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats
    Kara B Duffy
    Laboratory of Experimental Gerontology, Intramural Research Program, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Neurobiol Aging 29:1680-9. 2008
    ..These findings suggest that BB supplementation may protect against neurodegeneration and cognitive impairment mediated by excitotoxicity and oxidative stress...
  6. pmc Striatal lesions interfere with acquisition of a complex maze task in rats
    Paul J Pistell
    Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
    Behav Brain Res 197:138-43. 2009
    ..These results indicate that the 14-unit T-maze most likely is requires a large egocentric procedural learning component, and previously observed AAMI may involve age-related dysfunction of the striatum...
  7. doi request reprint Phosphodiesterase inhibition facilitates cognitive restoration in rodent models of age-related memory decline
    Bryan D Devan
    Laboratory of Comparative Neuropsychology, Psychology Department, Towson University, Towson, MD, USA Behavioral Neuroscience Section, Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Gerontology Research Center, Baltimore, MD, USA
    NeuroRehabilitation 34:101-11. 2014
    ..Previous studies have shown that cyclic nucleotide phosphodiesterase type 5 (PDE5) inhibition with the drugs sildenafil and vardenafil can enhance spatial performance and object recognition in rodent models of learning and memory...
  8. ncbi request reprint The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats
    Anne M Janas
    Laboratory of Experimental Gerontology, NIA NIH, Gerontology Research Center, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
    Life Sci 76:1073-81. 2005
    ..These findings demonstrate the ability of this drug to improve learning when cholinergic function has been impaired in a spatial memory task...
  9. ncbi request reprint The challenges of understanding mammalian cognition and memory-based behaviours: an interactive learning and memory systems approach
    Robert J McDonald
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alta, Canada AB T1K 3M4
    Neurosci Biobehav Rev 28:719-45. 2004
    ..Empirical and theoretical work directed at understanding the cognitive and non-cognitive processes associated with place learning in the water task and context conditioning during aversive events is also presented...
  10. ncbi request reprint Effect of D-serine on a delayed match-to-place task for the water maze
    Eric M Stouffer
    Department of Psychology, Laboratory of Comparative Neuropsychology, Towson University, Towson, MD 21252 0001, USA
    Behav Brain Res 152:447-52. 2004
    ..Rats administered D-serine (100 mg/kg, i.p.) before swim trials did not show a decrease in escape latencies, but did show an increase in swim time spent within the previous days' escape platform location...
  11. ncbi request reprint Partial reinforcement across trials impairs escape performance but spares place learning in the water maze
    Bryan D Devan
    Krasnow Institute for Advanced Study, George Mason University, Mail Stop 2A1, Fairfax, VA 22030 4444, USA
    Behav Brain Res 141:91-104. 2003
    ..We conclude that across-trial partial reinforcement procedures may promote response competition and mask evidence of place learning in addition to weakening escape performance late in training...
  12. ncbi request reprint A room with a view and a polarizing cue: individual differences in the stimulus control of place navigation and passive latent learning in the water maze
    Bryan D Devan
    Krasnow Institute for Advanced Study, George Mason University, Mail Stop 2A1, Fairfax, Virginia 22030 4444, USA
    Neurobiol Learn Mem 78:79-99. 2002
    ..Additional implications for neurobiological studies using a procedural pretraining design are discussed...