Richard Desper

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Getting a tree fast: Neighbor Joining, FastME, and distance-based methods
    Richard Desper
    Department of Biology, University College, London, United Kingdom
    Curr Protoc Bioinformatics . 2006
  2. ncbi request reprint Tumor classification using phylogenetic methods on expression data
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bldg 38A, Room 8N805, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Theor Biol 228:477-96. 2004
  3. ncbi request reprint Theoretical foundation of the balanced minimum evolution method of phylogenetic inference and its relationship to weighted least-squares tree fitting
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA
    Mol Biol Evol 21:587-98. 2004
  4. pmc A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis
    Richard Desper
    Computational Biology Branch, National Center for Biotechnology Information, National Institutes of Health, Department of Health and Human Services, Building 38A, Room 6S608, 8600 Rockville Pike, Bethesda, MD, USA
    Math Biosci 197:67-87. 2005
  5. ncbi request reprint Fast and accurate phylogeny reconstruction algorithms based on the minimum-evolution principle
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 45 Center Drive, Bethesda, MD 20892, USA
    J Comput Biol 9:687-705. 2002
  6. pmc A newly discovered human alpha-globin gene
    Sung Ho Goh
    Molecular Medicine Branch, National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Bldg 10 Rm 9B17, 10 Center Dr, Bethesda, MD 20892, USA
    Blood 106:1466-72. 2005
  7. ncbi request reprint Construction and analysis of tree models for chromosomal classification of diffuse large B-cell lymphomas
    Hui Yong Jiang
    Department of General Surgery, General Hospital of Shenyang Military Region, Shenyang, China
    World J Gastroenterol 13:1737-42. 2007

Detail Information

Publications7

  1. doi request reprint Getting a tree fast: Neighbor Joining, FastME, and distance-based methods
    Richard Desper
    Department of Biology, University College, London, United Kingdom
    Curr Protoc Bioinformatics . 2006
    ..It also describes how to estimate evolutionary distances from DNA and proteins, how to perform bootstrap analysis, and how to use CLUSTAL to compute both a sequence alignment and a phylogenetic tree...
  2. ncbi request reprint Tumor classification using phylogenetic methods on expression data
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bldg 38A, Room 8N805, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Theor Biol 228:477-96. 2004
    ..We tested this method on the SRBCT data set, and classified each tumor successfully...
  3. ncbi request reprint Theoretical foundation of the balanced minimum evolution method of phylogenetic inference and its relationship to weighted least-squares tree fitting
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA
    Mol Biol Evol 21:587-98. 2004
    ..Interestingly, the covarion parameter has little effect on the tree quality for any of the algorithms. FASTME is freely available on the web...
  4. pmc A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis
    Richard Desper
    Computational Biology Branch, National Center for Biotechnology Information, National Institutes of Health, Department of Health and Human Services, Building 38A, Room 6S608, 8600 Rockville Pike, Bethesda, MD, USA
    Math Biosci 197:67-87. 2005
    ..This allows the user to test hypotheses regarding the effect chromosomal aberrations have upon the cell cycle, cell growth rates, and time to population dominance...
  5. ncbi request reprint Fast and accurate phylogeny reconstruction algorithms based on the minimum-evolution principle
    Richard Desper
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 45 Center Drive, Bethesda, MD 20892, USA
    J Comput Biol 9:687-705. 2002
    ..Moreover, this BME scheme yields a very significant improvement over NJ and other distance-based algorithms, especially with large trees, in terms of topological accuracy...
  6. pmc A newly discovered human alpha-globin gene
    Sung Ho Goh
    Molecular Medicine Branch, National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Bldg 10 Rm 9B17, 10 Center Dr, Bethesda, MD 20892, USA
    Blood 106:1466-72. 2005
    ..These results suggest the human genome encodes a previously unrecognized globin member of the avian alpha-D family that is transcribed in a highly regulated pattern in erythroid cells...
  7. ncbi request reprint Construction and analysis of tree models for chromosomal classification of diffuse large B-cell lymphomas
    Hui Yong Jiang
    Department of General Surgery, General Hospital of Shenyang Military Region, Shenyang, China
    World J Gastroenterol 13:1737-42. 2007
    ....