K D Denicoff

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Relationship between prior course of illness and neuropsychological functioning in patients with bipolar disorder
    K D Denicoff
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Affect Disord 56:67-73. 1999
  2. ncbi request reprint Utility of the daily prospective National Institute of Mental Health Life-Chart Method (NIMH-LCM-p) ratings in clinical trials of bipolar disorder
    Kirk D Denicoff
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Depress Anxiety 15:1-9. 2002
  3. ncbi request reprint The Stanley Foundation Bipolar Treatment Outcome Network. I. Longitudinal methodology
    G S Leverich
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1272, USA
    J Affect Disord 67:33-44. 2001
  4. ncbi request reprint The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients
    T Suppes
    The Stanley Foundation Bipolar Network, 5430 Grosvenor Lane, Suite 200, Bethesda, MD 20814, USA
    J Affect Disord 67:45-59. 2001
  5. ncbi request reprint The Stanley Foundation Bipolar Network. I. Rationale and methods
    R M Post
    National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry Suppl 41:s169-76. 2001
  6. ncbi request reprint Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers
    R M Post
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892-1272, USA
    Bipolar Disord 3:259-65. 2001
  7. ncbi request reprint Relationship between prior course of illness and neuroanatomic structures in bipolar disorder: a preliminary study
    S O Ali
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Neuropsychiatry Neuropsychol Behav Neurol 14:227-32. 2001
  8. ncbi request reprint Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline
    R M Post
    Department of Health and Human Services, National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry 189:124-31. 2006
  9. ncbi request reprint Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology
    J A Quiroz
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, MD 20892, USA
    Mol Psychiatry 9:756-76. 2004
  10. ncbi request reprint Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
    Biol Psychiatry 60:1020-2. 2006

Detail Information

Publications24

  1. ncbi request reprint Relationship between prior course of illness and neuropsychological functioning in patients with bipolar disorder
    K D Denicoff
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Affect Disord 56:67-73. 1999
    ..This study investigated the relationship between prior course of illness and neuropsychological deficits in relatively high functioning outpatients with bipolar disorder...
  2. ncbi request reprint Utility of the daily prospective National Institute of Mental Health Life-Chart Method (NIMH-LCM-p) ratings in clinical trials of bipolar disorder
    Kirk D Denicoff
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Depress Anxiety 15:1-9. 2002
    ....
  3. ncbi request reprint The Stanley Foundation Bipolar Treatment Outcome Network. I. Longitudinal methodology
    G S Leverich
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1272, USA
    J Affect Disord 67:33-44. 2001
    ..This article describes the rationale for the Network, its guiding principles, methods, and study design to systematically assess the highly variable course of bipolar illness and its response to current and future treatments...
  4. ncbi request reprint The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients
    T Suppes
    The Stanley Foundation Bipolar Network, 5430 Grosvenor Lane, Suite 200, Bethesda, MD 20814, USA
    J Affect Disord 67:45-59. 2001
    ..This report describes the demographics and course of illness characteristics of this study population...
  5. ncbi request reprint The Stanley Foundation Bipolar Network. I. Rationale and methods
    R M Post
    National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry Suppl 41:s169-76. 2001
    ..CONCLUSIONS: Well-characterised patients are followed in a detailed continuous longitudinal fashion in both opportunistic case series and double-blind, randomised controlled trials with reliable and validated measures...
  6. ncbi request reprint Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers
    R M Post
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892-1272, USA
    Bipolar Disord 3:259-65. 2001
    ..Individual data on each drug will be assessed in the next phase of the study after more subjects are recruited and the blind is broken...
  7. ncbi request reprint Relationship between prior course of illness and neuroanatomic structures in bipolar disorder: a preliminary study
    S O Ali
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Neuropsychiatry Neuropsychol Behav Neurol 14:227-32. 2001
    ..CONCLUSIONS: Additional studies are needed to both replicate and further examine the association of prior course of illness and larger hippocampal and ventricular volumes in bipolar disorder...
  8. ncbi request reprint Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline
    R M Post
    Department of Health and Human Services, National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry 189:124-31. 2006
    ..Few studies have examined the relative risks of switching into hypomania or mania associated with second-generation antidepressant drugs in bipolar depression...
  9. ncbi request reprint Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology
    J A Quiroz
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, MD 20892, USA
    Mol Psychiatry 9:756-76. 2004
    ..While the task of developing novel medications for bipolar disorder is truly daunting, these and similar approaches will ultimately lead to better medications for the millions who suffer from this devastating illness...
  10. ncbi request reprint Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
    Biol Psychiatry 60:1020-2. 2006
    ..The results of pilot trials suggest that omega-3 fatty acids may have efficacy in the treatment of mood symptoms in bipolar disorder...
  11. ncbi request reprint Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers
    Gabriele S Leverich
    Biological Psychiatry Branch, National Institutes of Mental Health, Bldg 10 Room 3S239, 10 Center Drive, MSC 1272, Bethesda, MD 20892 1272, USA
    Am J Psychiatry 163:232-9. 2006
    ..The authors examined the comparative risks of switches in mood polarity into hypomania or mania during acute and continuation trials of adjunctive antidepressant treatment of bipolar depression...
  12. ncbi request reprint Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients
    Ralph W Kupka
    Altrecht Institute for Mental Health Care, Tolsteegsingel 2A, 3582 AC Utrecht, Netherlands
    Am J Psychiatry 162:1273-80. 2005
    ..To detect risk factors for rapid cycling in bipolar disorder, the authors compared characteristics of rapid-cycling and non-rapid-cycling patients both from a categorical and a dimensional perspective...
  13. ncbi request reprint An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression
    Carlos A Zarate
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, Maryland, USA
    Biol Psychiatry 57:430-2. 2005
    ..This study was conducted to determine the efficacy and safety of riluzole, a glutamate-modulating agent, in bipolar depression...
  14. ncbi request reprint Pramipexole for bipolar II depression: a placebo-controlled proof of concept study
    Carlos A Zarate
    Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institute of Health, Department of Human and Health Services, Bethesda, Maryland, USA
    Biol Psychiatry 56:54-60. 2004
    ..The current study was undertaken as a proof of the concept that dopamine agonists will be effective in patients with bipolar II depression...
  15. ncbi request reprint Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system
    Carlos A Zarate
    Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 1003:273-91. 2003
    ....
  16. ncbi request reprint Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method
    Robert M Post
    Stanley Foundation Bipolar Network and Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 12723, USA
    J Clin Psychiatry 64:680-90; quiz 738-9. 2003
    ..The detailed course and pattern of illness emerging despite comprehensive treatment with mood stabilizers and adjunctive agents have previously not been well delineated...
  17. ncbi request reprint Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network
    Gabriele S Leverich
    Stanley Foundation Bipolar Treatment Outcome Network, Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD 20892 1272, USA
    J Clin Psychiatry 64:506-15. 2003
    ..We investigated demographic and course-of-illness variables to better understand the incidence and potential clinical correlates of serious suicide attempts in 648 outpatients with bipolar disorder...
  18. ncbi request reprint Tiagabine in treatment refractory bipolar disorder: a clinical case series
    Trisha Suppes
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Bipolar Disord 4:283-9. 2002
    ..We sought to evaluate the effectiveness of tiagabine added to ongoing medication regimens in patients with bipolar disorder inadequately responsive to or intolerant of usual treatments...
  19. ncbi request reprint High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure
    Ralph W Kupka
    Altrecht Centre for Mental Health Care and University Medical Centre Utrecht, Vrouwjuttenhof 18, 3512 PZ Utrecht, The Netherlands
    Biol Psychiatry 51:305-11. 2002
    ..We assessed the prevalence of thyroperoxidase antibodies (TPO-Abs) and thyroid failure in outpatients with bipolar disorder compared with two control groups...
  20. ncbi request reprint Early physical and sexual abuse associated with an adverse course of bipolar illness
    Gabriele S Leverich
    Stanley Foundation Bipolar Treatment Outcome Network and the Biological Psychiatry Branch, National Institute of Mental Health, Building 10, Room 3S 239, Bethesda, MD 20892 1272, USA
    Biol Psychiatry 51:288-97. 2002
    ..There is growing awareness of the association between physical and sexual abuse and subsequent development of psychopathology, but little is known, however, about their relationship to the longitudinal course of bipolar disorder...
  21. ncbi request reprint A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:426-34. 2007
    ..The objective of this study was to compare sibutramine and topiramate as adjunctive treatments for psychotropic-associated weight gain in overweight or obese outpatients with BD...
  22. ncbi request reprint Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness
    Paul E Keck
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Compr Psychiatry 44:263-9. 2003
    ..The lack of observable prognostic impact may have been, in part, due to the relatively high morbidity and poor functional outcome of a substantial portion of the total cohort...
  23. ncbi request reprint High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder
    M Nadine Breunis
    Department of Immunology, Erasmus University Rotterdam MNB, HAD, Rotterdam, The Netherlands
    Biol Psychiatry 53:157-65. 2003
    ..In the present study, we investigated other signs of immune activation in bipolar patients, in particular an activation of the T cell system...
  24. ncbi request reprint Correlates of overweight and obesity in 644 patients with bipolar disorder
    Susan L McElroy
    Stanley Foundation Bipolar Treatment Outcome Network, Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267 0559, USA
    J Clin Psychiatry 63:207-13. 2002
    ..Overweight and obesity are common clinical problems encountered in the treatment of bipolar disorder. We therefore assessed the prevalence and clinical correlates of overweight, obesity, and extreme obesity in 644 bipolar patients...