Jurrien Dean


Affiliation: National Institutes of Health
Country: USA


  1. Tokuhiro K, Dean J. Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy. Dev Cell. 2018;46:627-640.e5 pubmed publisher
    ..This transient, post-fertilization block to sperm penetration provides a temporal window to complete the cleavage of ZP2, which prevents sperm binding to ensure monospermy. ..
  2. Zhou L, Canagarajah B, Zhao Y, Baibakov B, Tokuhiro K, Maric D, et al. BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice. Dev Cell. 2017;40:453-466.e5 pubmed publisher
    ..Thus, our study identifies BTBD18 as a specific controller for transcription activation through RNA polymerase II elongation at a subset of genomic piRNA loci. ..
  3. Shin S, Vogt E, Jimenez Movilla M, Baibakov B, Dean J. Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017;8:1643 pubmed publisher
    ..Thus, the N-terminus of DPPA3 has a significant role in cytoplasmic vesicular trafficking in addition to its previously reported nuclear function. ..