B J Davis

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
    B J Davis
    Laboratory of Women s, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 60:5414-9. 2000
  2. ncbi request reprint Mercury vapor and female reproductive toxicity
    B J Davis
    National Institute of Environmental Sciences, MD A2 01, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 59:291-6. 2001
  3. ncbi request reprint Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta
    B J Davis
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Endocrinology 140:2685-95. 1999
  4. ncbi request reprint Reproductive endocrinology and toxicological pathology over the life span of the female rodent
    B J Davis
    Laboratory of Women s Health, NIEHS, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 29:77-83. 2001
  5. ncbi request reprint Ovarian luteal cell toxicity of ethylene glycol monomethyl ether and methoxy acetic acid in vivo and in vitro
    B J Davis
    Department of Microbiology, Parasitology, and Pathology, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Toxicol Appl Pharmacol 142:328-37. 1997
  6. ncbi request reprint Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol
    L M Bennett
    Laboratories of Molecular Carcinogenesis, NIH, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 60:3461-9. 2000
  7. ncbi request reprint BRCA2-null embryonic survival is prolonged on the BALB/c genetic background
    L M Bennett
    Laboratory of Molecular Carcinogenesis, National Institutes of Health, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Mol Carcinog 28:174-83. 2000
  8. ncbi request reprint Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency
    L M Bennett
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 29:117-25. 2001
  9. ncbi request reprint The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats
    R J Smialowicz
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, ETD MD 92, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Toxicol Sci 61:164-75. 2001
  10. ncbi request reprint Extragonadal teratocarcinoma in chimeric mice
    P Blackshear
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Vet Pathol 36:457-60. 1999

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
    B J Davis
    Laboratory of Women s, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 60:5414-9. 2000
    ..The tumor type induced by TCDD in this experimental system is the same histological subtype as that reported from an early study of youngsters exposed during an industrial accident in Seveso, Italy...
  2. ncbi request reprint Mercury vapor and female reproductive toxicity
    B J Davis
    National Institute of Environmental Sciences, MD A2 01, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 59:291-6. 2001
    ..These studies indicate that exposure to Hg degrees vapor altered estrous cyclicity, but had no significant effect on ovulation, implantation, or maintenance of first pregnancy during exposure of short duration in female rats...
  3. ncbi request reprint Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta
    B J Davis
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Endocrinology 140:2685-95. 1999
    ....
  4. ncbi request reprint Reproductive endocrinology and toxicological pathology over the life span of the female rodent
    B J Davis
    Laboratory of Women s Health, NIEHS, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 29:77-83. 2001
    ..Examples are used to illustrate the consequences of exposures at different times and with different outcomes...
  5. ncbi request reprint Ovarian luteal cell toxicity of ethylene glycol monomethyl ether and methoxy acetic acid in vivo and in vitro
    B J Davis
    Department of Microbiology, Parasitology, and Pathology, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Toxicol Appl Pharmacol 142:328-37. 1997
    ..Thus, these studies establish that the ovarian luteal cell is a target of EGME and MAA in vivo and in vitro and that the effect on luteal cell progesterone production is likely independent of LH-stimulated cAMP pathways...
  6. ncbi request reprint Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol
    L M Bennett
    Laboratories of Molecular Carcinogenesis, NIH, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 60:3461-9. 2000
    ....
  7. ncbi request reprint BRCA2-null embryonic survival is prolonged on the BALB/c genetic background
    L M Bennett
    Laboratory of Molecular Carcinogenesis, National Institutes of Health, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Mol Carcinog 28:174-83. 2000
    ..5 BALB/c(B2-/-) embryos that was comparable to Brca2-heterozygous littermates. Thus, the Brca1 and Brca2 transcripts are expressed independently of one another in Brca1- and Brca2-null embryos. Mol. Carcinog. 28:174-183, 2000...
  8. ncbi request reprint Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency
    L M Bennett
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Toxicol Pathol 29:117-25. 2001
    ..The Apc mutation-driven phenotypes were not modified by mutation of Brca2, perhaps because Brca2 acts in a hormonally dependent pathway of mammary carcinogenesis...
  9. ncbi request reprint The effects of perinatal/juvenile heptachlor exposure on adult immune and reproductive system function in rats
    R J Smialowicz
    Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, ETD MD 92, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Toxicol Sci 61:164-75. 2001
    ..Suppression of these antibody responses persisted for up to 20 weeks after the last exposure to H, at a total exposure of approximately 1500 microg H/kg/rat...
  10. ncbi request reprint Extragonadal teratocarcinoma in chimeric mice
    P Blackshear
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Vet Pathol 36:457-60. 1999
    ..These cases of extragonadal teratocarcinoma, a rarely reported tumor, may be related to the genetic predisposition of the 129/Ola mouse strain used to generate the embryonic stem cells...
  11. ncbi request reprint Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta
    J F Couse
    Receptor Biology Section, Laboratory of Reproductive and Developmental Toxicology, Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Science 286:2328-31. 1999
    ....
  12. ncbi request reprint Early changes in sex hormones are not evident in mice exposed to the uterine carcinogens chloroethane or bromoethane
    J R Bucher
    National Institute of Environmental Health Sciences, Mantech Inc, Research Triangle Park, North Carolina
    Toxicol Appl Pharmacol 130:169-73. 1995
    ..Thus, the findings suggest that early changes in circulating sex hormones are not important contributing factors in the uterine neoplasia caused by these chemicals...
  13. ncbi request reprint Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice
    P E Blackshear
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Oncogene 16:61-8. 1998
    ..Thus, while Brca1 and Brca2 share concordant cell-specific patterns of expression in most proliferating tissues, these observations suggest that they may have distinct roles during meiosis...
  14. ncbi request reprint Disruption of cyclooxygenase genes in mice
    J F Mahler
    Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 24:717-9. 1996
  15. ncbi request reprint Brca1 is expressed independently of hormonal stimulation in the mouse ovary
    K W Phillips
    National Institute of Environmental Health Sciences, Research Triangle Park 27709, USA
    Lab Invest 76:419-25. 1997
    ....
  16. ncbi request reprint Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells
    T N Lovekamp
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, 27695, USA
    Toxicol Appl Pharmacol 172:217-24. 2001
    ..Moreover, the suppression of estradiol by MEHP is likely mediated through its action on aromatase transcript levels independent of cAMP-stimulated regulation...
  17. ncbi request reprint The effects of perinatal tebuconazole exposure on adult neurological, immunological, and reproductive function in rats
    V C Moser
    Neurotoxicology Division and Environmental Toxicology Division, National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Sci 62:339-52. 2001
    ..Thus, perinatal exposure to tebuconazole produced neurobehavioral deficits and neuropathology in rats, but did not alter immunological or reproductive function...
  18. ncbi request reprint Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy
    B J Davis
    Diabetic Complications Group, Baker Heart Research Institute, P O Box 6492, Melbourne, 8008 Victoria, Australia
    Diabetologia 46:961-71. 2003
    ..The major endpoints were reductions in systemic blood pressure, albuminuria and renal structural injury...