Brandon J Cuthbertson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Discovery of synthetic penaeidin activity against antibiotic-resistant fungi
    Brandon J Cuthbertson
    National Institutes of Health National Institute of Environmental Health Sciences, PO Box 12233 MD F3 04, Research Triangle Park, NC 27709 2233, USA
    Chem Biol Drug Des 68:120-7. 2006
  2. pmc Diversity in penaeidin antimicrobial peptide form and function
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, NIH NIEHS, P O Box 12233 MD F3 04, 111 TW Alexander Drive, Research Triangle Park, NC 27709 2233, USA
    Dev Comp Immunol 32:167-81. 2008
  3. doi request reprint Chapter 4. Evaluating the control of mRNA decay in fission yeast
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Methods Enzymol 449:73-95. 2008
  4. pmc Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    J Biol Chem 283:2586-94. 2008
  5. pmc A new class (penaeidin class 4) of antimicrobial peptides from the Atlantic white shrimp (Litopenaeus setiferus) exhibits target specificity and an independent proline-rich-domain function
    Brandon J Cuthbertson
    Marine Biomedicine and Environmental Sciences, Medical University of South Carolina, 221 Fort Johnson Road, Charleston, SC 29412, USA
    Biochem J 381:79-86. 2004
  6. ncbi request reprint Diversity of the penaeidin antimicrobial peptides in two shrimp species
    Brandon J Cuthbertson
    Marine Biomedicine and Environmental Sciences Program, Medical University of South Carolina, Charleston 29425, USA
    Immunogenetics 54:442-5. 2002
  7. ncbi request reprint Alternative splicing of major histocompatibility complex class II DXB transcripts in Xiphophorus fishes
    Kelly E Roney
    Department of Biology, Howell Science Complex, East Carolina University, Greenville, NC 27858, USA
    Immunogenetics 56:462-6. 2004
  8. ncbi request reprint Solution structure of synthetic penaeidin-4 with structural and functional comparisons with penaeidin-3
    Brandon J Cuthbertson
    Centre de Biochimie Structurale, CNRS UMR 5048, INSERM U414, Universite Montpellier 1, Faculte de Pharmacie, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France
    J Biol Chem 280:16009-18. 2005

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Discovery of synthetic penaeidin activity against antibiotic-resistant fungi
    Brandon J Cuthbertson
    National Institutes of Health National Institute of Environmental Health Sciences, PO Box 12233 MD F3 04, Research Triangle Park, NC 27709 2233, USA
    Chem Biol Drug Des 68:120-7. 2006
    ..The proline-rich domain of penaeidin class 4 shows the highest relative antimicrobial activity, while exhibiting no cytotoxicity to human monocytes, and therefore stands out as a potential peptide therapeutic...
  2. pmc Diversity in penaeidin antimicrobial peptide form and function
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, NIH NIEHS, P O Box 12233 MD F3 04, 111 TW Alexander Drive, Research Triangle Park, NC 27709 2233, USA
    Dev Comp Immunol 32:167-81. 2008
    ....
  3. doi request reprint Chapter 4. Evaluating the control of mRNA decay in fission yeast
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Methods Enzymol 449:73-95. 2008
    ..We hope to use this convenient experimental system to unravel the mechanism by which TTP family members, in this and other organisms, bind to mRNAs and promote their instability...
  4. pmc Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe
    Brandon J Cuthbertson
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T W Alexander Drive, Research Triangle Park, NC 27709, USA
    J Biol Chem 283:2586-94. 2008
    ..zfs1 and its targets in S. pombe represent a useful model system for studies of zinc finger protein/AU-rich element interactions that result in mRNA decay...
  5. pmc A new class (penaeidin class 4) of antimicrobial peptides from the Atlantic white shrimp (Litopenaeus setiferus) exhibits target specificity and an independent proline-rich-domain function
    Brandon J Cuthbertson
    Marine Biomedicine and Environmental Sciences, Medical University of South Carolina, 221 Fort Johnson Road, Charleston, SC 29412, USA
    Biochem J 381:79-86. 2004
    ....
  6. ncbi request reprint Diversity of the penaeidin antimicrobial peptides in two shrimp species
    Brandon J Cuthbertson
    Marine Biomedicine and Environmental Sciences Program, Medical University of South Carolina, Charleston 29425, USA
    Immunogenetics 54:442-5. 2002
    ..Phylogenetic analysis indicates that all classes of penaeidin were likely present in both species prior to speciation...
  7. ncbi request reprint Alternative splicing of major histocompatibility complex class II DXB transcripts in Xiphophorus fishes
    Kelly E Roney
    Department of Biology, Howell Science Complex, East Carolina University, Greenville, NC 27858, USA
    Immunogenetics 56:462-6. 2004
    ..The alternative splice pattern and the divergence of DXB from DAB suggest that in fish, DXB may have an alternate function. Alternative splicing transcripts of DXB may allow for signaling and localization of DXB within the cell...
  8. ncbi request reprint Solution structure of synthetic penaeidin-4 with structural and functional comparisons with penaeidin-3
    Brandon J Cuthbertson
    Centre de Biochimie Structurale, CNRS UMR 5048, INSERM U414, Universite Montpellier 1, Faculte de Pharmacie, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France
    J Biol Chem 280:16009-18. 2005
    ..However, the tertiary structure of the cysteine-rich domain and indeed the overall structure of penaeidins are conserved across classes...