Research Topics
| E W CowenSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Eruptive linear papules on the abdomen of a woman with ascitesEdward W Cowen
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Am Acad Dermatol 51:75-8. 2004
Differentiation of tumour-stage mycosis fungoides, psoriasis vulgaris and normal controls in a pilot study using serum proteomic analysisE W Cowen
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Br J Dermatol 157:946-53. 2007..The resultant 'proteomic signature' has been used to differentiate benign and malignant diseases, enable disease prognosis, and monitor response to therapy...
Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazoleEdward W Cowen
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Am Acad Dermatol 62:31-7. 2010..Voriconazole is a broad-spectrum antifungal agent associated with photosensitivity and accelerated photoaging. A possible link with aggressive squamous cell carcinoma (SCC) has also been reported...
Epidermal growth factor receptor inhibitors: a new era of drug reactions in a new era of cancer therapyEdward W Cowen
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Am Acad Dermatol 56:514-7. 2007
Voriconazole-induced phototoxicity masquerading as chronic graft-versus-host disease of the skin in allogeneic hematopoietic cell transplant recipientsAsha R Patel
Dermatology Branch, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
Biol Blood Marrow Transplant 15:370-6. 2009..A high index of suspicion for this adverse reaction in the post-alloHCT setting will prevent misdiagnosis and avoid inappropriate therapy for cGVHD...
Determinants of functional performance in long-term survivors of allogeneic hematopoietic stem cell transplantation with chronic graft-versus-host disease (cGVHD)S A Mitchell
Nursing Research, Clinical Center, National Institutes of Health, Bethesda, MD 20852, USA
Bone Marrow Transplant 45:762-9. 2010..004). Results suggest two possible mechanisms underlying impaired functional performance in survivors with cGVHD and underscore the importance of testing interventions to enhance functional capacity and reduce symptom bother...
Chronic granulomatous disease as a risk factor for autoimmune diseaseSuk See De Ravin
National Institutes of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892 1456, USA
J Allergy Clin Immunol 122:1097-103. 2008..The presence and type of autoimmune disease have important treatment implications for patients with CGD...
Dyskeratosis congenita: the first NIH clinical research workshopSharon A Savage
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
Pediatr Blood Cancer 53:520-3. 2009..dcoutreach.com/). Ongoing, open collaboration between the clinical, scientific, and family communities is required for continued improvement in our understanding of DC and the clinical consequences of telomeric defects...
Measuring therapeutic response in chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group reportSteven Z Pavletic
National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1203, USA
Biol Blood Marrow Transplant 12:252-66. 2006..The proposed response criteria are based on current expert consensus opinion and are intended to improve consistency in the conduct and reporting of chronic GVHD trials, but their use remains to be demonstrated in practice...
Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluationMatin M Imanguli
Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Biol Blood Marrow Transplant 16:1362-9. 2010..Formal evaluation of salivary function using standardized criteria is needed, and this could be incorporated as an outcome measure in clinical trials of cGVHD...
Hypomorphic Rag mutations can cause destructive midline granulomatous diseaseSuk See De Ravin
Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Blood 116:1263-71. 2010..This study was registered at www.clinicaltrials.gov as #NCT00128973...
Oral chronic graft-vs.-host disease characterization using the NIH scaleH Fassil
Experimental Transplantation and Immunology Branch, National Cancer Institute, NIH, 10 Center Drive, Bethesda, MD 20892, USA
J Dent Res 91:45S-51S. 2012..We propose the use of >2 points on the NIH scale as a reproducible definition of clinically significant oral cGVHD, which may be useful in clinical settings or as eligibility criterion or as an endpoint in clinical trials...
Skin reactions in a subset of patients with stage IV melanoma treated with anti-cytotoxic T-lymphocyte antigen 4 monoclonal antibody as a single agentSamer H Jaber
Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-1908, USA
Arch Dermatol 142:166-72. 2006..Specific features of skin eruption associated with anti-CTLA-4 resemble those described for maculopapular reactions to medications...
Magnetic resonance imaging in sclerotic-type chronic graft-vs-host diseaseJason Clark
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Arch Dermatol 145:918-22. 2009....
Localization of sclerotic-type chronic graft-vs-host disease to sites of skin injury: potential insight into the mechanism of isomorphic and isotopic responsesKathryn J Martires
Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, Bethesda, MD 20892, USA
Arch Dermatol 147:1081-6. 2011....
Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: utility of PCR for early recognition and therRachel Rau
Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1104, USA
Pediatr Infect Dis J 27:265-8. 2008..She was treated with acyclovir and subsequently developed VZV antigen-positive zoster. Detection of VZV DNA in blood may be useful for early diagnosis in immunocompromised hosts who present with zoster without skin lesions...
Gynecomastia and mucosal lentigines in an 8-year-old boyLaura Winterfield
Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-1908, USA
J Am Acad Dermatol 53:660-2. 2005
Thrombocytopenia, multiple mucosal squamous cell carcinomas, and dyspigmentationMarisa Braun
Dermatology Branch, Center for Cancer Research, Division of Cancer Epidemiology and Research, National Institutes of Health, Bethesda, Maryland, USA
J Am Acad Dermatol 54:1056-9. 2006
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonistIvona Aksentijevich
National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, USA
N Engl J Med 360:2426-37. 2009..We report a disorder caused by mutations of IL1RN, which encodes the interleukin-1-receptor antagonist, with prominent involvement of skin and bone...
Multiple painful cutaneous nodules and renal massAnne Rothman
Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1908, USA
J Am Acad Dermatol 55:683-6. 2006
National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group reportAlexandra H Filipovich
Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
Biol Blood Marrow Transplant 11:945-56. 2005..It is currently recommended that systemic therapy be considered for patients who meet criteria for chronic GVHD of moderate to severe global severity...
Proteomic patterns for classification of ovarian cancer and CTCL serum samples utilizing peak pairs indicative of post-translational modificationsChenwei Liu
Clinical Proteomics Reference Laboratory, Gaithersburg, MD, USA
Proteomics 7:4045-52. 2007..This simple peak picking technique could be used to guide identification of important peak pairs involved in the disease process...
Keratoacanthomas associated with sorafenib therapyHeidi H Kong
J Am Acad Dermatol 56:171-2. 2007
The isomorphic response in morphealike chronic graft-vs-host diseaseAsha R Patel
Arch Dermatol 144:1229-31. 2008
