Shay Covo

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Understanding the origins of UV-induced recombination through manipulation of sister chromatid cohesion
    Shay Covo
    Chromosome Stability Section, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences NIEHS, National Institutes of Health NIH, Research Triangle Park, NC, USA
    Cell Cycle 11:3937-44. 2012
  2. pmc RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition
    Shay Covo
    Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA
    DNA Repair (Amst) 11:317-23. 2012
  3. pmc Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes
    Shay Covo
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences NIEHS, National Institutes of Health NIH, Research Triangle Park, North Carolina, United States of America
    PLoS Genet 6:e1001006. 2010

Detail Information

Publications3

  1. pmc Understanding the origins of UV-induced recombination through manipulation of sister chromatid cohesion
    Shay Covo
    Chromosome Stability Section, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences NIEHS, National Institutes of Health NIH, Research Triangle Park, NC, USA
    Cell Cycle 11:3937-44. 2012
    ..This notion is supported by a direct physical observation of UV-induced DSBs that are dependent on nucleotide excision repair. However, a significant role of nonDSB intermediates in UV-induced recombination cannot be excluded...
  2. pmc RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibition
    Shay Covo
    Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA
    DNA Repair (Amst) 11:317-23. 2012
    ..These results have implications for developing drug enhancers as well as for understanding mechanisms of drug resistance in cells compromised for DNA damage checkpoint...
  3. pmc Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes
    Shay Covo
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences NIEHS, National Institutes of Health NIH, Research Triangle Park, North Carolina, United States of America
    PLoS Genet 6:e1001006. 2010
    ..The effects of limited amounts of Mcd1and Smc3 indicate that small changes in cohesin levels may increase the risk of genome instability, which may lead to genetic diseases and cancer...