Research Topics
| P S ConvilleSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Multiple copies of the 16S rRNA gene in Nocardia nova isolates and implications for sequence-based identification proceduresPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892 1508, USA
J Clin Microbiol 43:2881-5. 2005....
Nocardia veterana as a pathogen in North American patientsPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland 20892, USA
J Clin Microbiol 41:2560-8. 2003..veterana from the related species Nocardia africana and N. nova because of the very high degree of 16S rRNA gene similarity among them...
Analysis of secA1 gene sequences for identification of Nocardia speciesPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, U S Department of Health and Human Services, 10 Center Drive, MSC 1508, Bethesda, MD 20892 1508, USA
J Clin Microbiol 44:2760-6. 2006..Sequencing of the secA1 gene, and using deduced amino acid sequences of the SecA1 protein, may provide a more discriminative and precise method for the identification of Nocardia isolates than 16S rRNA gene sequencing...
Organisms designated as Nocardia asteroides drug pattern type VI are members of the species Nocardia cyriacigeorgicaPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, 10 Center Drive, MSC 1508, Bethesda, MD 20892 1508, USA
J Clin Microbiol 45:2257-9. 2007..However, DNA-DNA hybridization results confirm that Nocardia asteroides drug pattern type VI, which has long been recognized as a common and significant pathogen in the United States, belongs to the species N. cyriacigeorgica...
Lack of usefulness of carbon utilization tests for identification of Mycobacterium mucogenicumP S Conville
Microbiology Service, Department of Laboratory Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1508, USA
J Clin Microbiol 39:2725-8. 2001..Molecular or cell wall analysis may be the best technique to employ for accurate identification of M. mucogenicum...
Identification of nocardia species by restriction endonuclease analysis of an amplified portion of the 16S rRNA geneP S Conville
Microbiology Service, Clinical Pathology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
J Clin Microbiol 38:158-64. 2000..The PCR and REA technique described appears useful both for the identification of clinical isolates of Nocardia and for the detection of new or unusual species...
Variables affecting results of sodium chloride tolerance test for identification of rapidly growing mycobacteriaP S Conville
Microbiology Service, Clinical Pathology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1508, USA
J Clin Microbiol 36:1555-9. 1998..chelonae. Molecular methodologies are probably the most reliable means for the identification of rapidly growing mycobacteria and should be used, if possible, when unequivocal species identification is of particular importance...
Nocardia wallacei sp. nov. and Nocardia blacklockiae sp. nov., human pathogens and members of the "Nocardia transvalensis Complex"Patricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, 10 Center Drive, MSC 1508, Bethesda, MD 20892 1508, USA
J Clin Microbiol 46:1178-84. 2008..Case studies demonstrating the pathogenicity of N. wallacei and N. blacklockiae are presented. The type strain of N. wallacei is ATCC 49873 (DSM 45136), and that of N. blacklockiae is ATCC 700035 (DSM 45135)...
Nocardia kruczakiae sp. nov., a pathogen in immunocompromised patients and a member of the "N. nova complex"Patricia S Conville
Microbiology Service, Department of Laboratroy Medicine, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1508, USA
J Clin Microbiol 42:5139-45. 2004..nova complex" can be used to designate isolates such as these that phenotypically resemble N. nova but that have not been definitively characterized by 16S rRNA gene sequencing or DNA-DNA hybridization...
Effect of PANTA on growth of Mycobacterium kansasii in BACTEC 12B mediumP S Conville
Clinical Pathology Department, Warren G Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1508, USA
J Clin Microbiol 33:2012-5. 1995..All isolates showed some degree of inhibition on at least one of these selective media...
Evaluation of the integrated database network system (IDNS) SmartGene software for analysis of 16S rRNA gene sequences for identification of Nocardia speciesPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
J Clin Microbiol 48:2995-8. 2010..Discordant identifications were due to inadequate centroid length (3 species), inaccurate or insufficient entries in the public databases (5 species), and heterogeneous sequences among members of a species (1 species)...
"Mycobacterium tilburgii," a newly described, uncultivated opportunistic pathogenTara N Palmore
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
J Clin Microbiol 47:1585-7. 2009..The case illustrates the diagnostic utility of sequence analysis of the 16S rRNA gene directly from clinical specimens...
Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family AcetobacteraceaeDavid E Greenberg
Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, US Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Syst Evol Microbiol 56:2609-16. 2006..nov., sp. nov. is proposed. The type strain is CGDNIH1T (=ATCC BAA-1260T=DSM 17861T)...
Analysis of multiple differing copies of the 16S rRNA gene in five clinical isolates and three type strains of Nocardia species and implications for species assignmentPatricia S Conville
Microbiology Service, Department of Laboratory Medicine, Warren G Magnuson Clinical Center, National Institutes of Health, 10 Center Drive, MSC 1508, Bethesda, MD 20892 1508, USA
J Clin Microbiol 45:1146-51. 2007..A broader species concept than that currently in vogue may be required to accommodate such organisms...
Clarithromycin lowers plasma zidovudine levels in persons with human immunodeficiency virus infectionM A Polis
National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, Maryland 20982 1880, USA
Antimicrob Agents Chemother 41:1709-14. 1997..Drug interactions should be carefully evaluated in persons with advanced human immunodeficiency virus infection who are receiving multiple pharmacologic agents...
Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolatesChiara Ripamonti
Critical Care Medicine Department, NIH Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
J Infect Dis 200:1616-22. 2009..Our results highlight the presence of a remarkable diversity in human Pneumocystis strains. RFLP may be very useful for studying clusters of PCP in immunosuppressed patients, to determine whether there is a common source of infection...
Nocardia infection in chronic granulomatous diseaseSusan E Dorman
Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Clin Infect Dis 35:390-4. 2002..Nocardia infections in patients with CGD are not usually fatal if treated properly, and prophylaxis with IFN-gamma and a sulfonamide may protect against dissemination...
Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomyBarbara A Brown-Elliott
Department of Microbiology, The University of Texas Health Center, 11937 U.S. Highway 271, Tyler, 75708, USA
Clin Microbiol Rev 19:259-82. 2006..This review characterizes the currently known pathogenic species of Nocardia, including clinical disease, drug susceptibility, and methods of identification...
Evaluation of partial 16S ribosomal DNA sequencing for identification of nocardia species by using the MicroSeq 500 system with an expanded databaseJoann L Cloud
ARUP Institute for Clinical and Experimental Pathology, Department of Pathology, University of Utah, Salt Lake City, Utah, USA
J Clin Microbiol 42:578-84. 2004..With an expanded database, the MicroSeq 500 system for partial 16S rDNA was able to correctly identify the human pathogens N. brasiliensis, N. cyriacigeorgica, N. farcinica, N. nova, N. otitidiscaviarum, and N. veterana...
Nocardia cyriacigeorgica--an established rather than an emerging pathogenFrank G Witebsky
J Clin Microbiol 46:2469; author reply 2469-70. 2008
Multisite reproducibility of results obtained by two broth dilution methods for susceptibility testing of Mycobacterium avium complexGail L Woods
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
J Clin Microbiol 41:627-31. 2003..Both techniques require appropriate validation and continued documentation of proficiency...
