Carolyn C Compton

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Key issues in reporting common cancer specimens: problems in pathologic staging of colon cancer
    Carolyn C Compton
    Department of Pathology, McGill University Health Center, Montreal, Quebec
    Arch Pathol Lab Med 130:318-24. 2006
  2. ncbi request reprint Getting to personalized cancer medicine: taking out the garbage
    Carolyn Compton
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, Maryland 20892 2580, USA
    Cancer 110:1641-3. 2007
  3. ncbi request reprint Optimal pathologic staging: defining stage II disease
    Carolyn C Compton
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, MD 20892, USA
    Clin Cancer Res 13:6862s-70s. 2007
  4. ncbi request reprint The cancer and leukemia group B pathology committee at 50
    Carolyn Compton
    National Cancer Institute, NIH, Bethesda, Maryland, USA
    Clin Cancer Res 12:3617s-21s. 2006
  5. ncbi request reprint Surgical pathology for the oncology patient in the age of standardization: of margins, micrometastasis, and molecular markers
    Carolyn C Compton
    Department of Pathology, McGill University Health Center, Montreal, Canada
    Semin Radiat Oncol 13:382-8. 2003
  6. ncbi request reprint Scoring of p53, VEGF, Bcl-2 and APAF-1 immunohistochemistry and interobserver reliability in colorectal cancer
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, QC, Canada
    Mod Pathol 19:1236-42. 2006
  7. ncbi request reprint VEGF as a predictive marker of rectal tumor response to preoperative radiotherapy
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Cancer 104:2517-21. 2005
  8. ncbi request reprint The predictive value of apoptosis protease-activating factor 1 in rectal tumors treated with preoperative, high-dose-rate brachytherapy
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Cancer 106:284-6. 2006
  9. pmc 2009 Biospecimen research network symposium: advancing cancer research through biospecimen science
    Helen M Moore
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 69:6770-2. 2009
  10. ncbi request reprint Colorectal carcinoma: diagnostic, prognostic, and molecular features
    Carolyn C Compton
    Department of Pathology and University Health Center, McGill University, Montreal, Quebec
    Mod Pathol 16:376-88. 2003

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Key issues in reporting common cancer specimens: problems in pathologic staging of colon cancer
    Carolyn C Compton
    Department of Pathology, McGill University Health Center, Montreal, Quebec
    Arch Pathol Lab Med 130:318-24. 2006
    ..Standardized pathologic assessment is a quality measure for cancer care...
  2. ncbi request reprint Getting to personalized cancer medicine: taking out the garbage
    Carolyn Compton
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, Maryland 20892 2580, USA
    Cancer 110:1641-3. 2007
  3. ncbi request reprint Optimal pathologic staging: defining stage II disease
    Carolyn C Compton
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, MD 20892, USA
    Clin Cancer Res 13:6862s-70s. 2007
    ..The presence of these features may help to identify patients for whom surgery alone will not be curative and adjuvant therapies may be appropriate...
  4. ncbi request reprint The cancer and leukemia group B pathology committee at 50
    Carolyn Compton
    National Cancer Institute, NIH, Bethesda, Maryland, USA
    Clin Cancer Res 12:3617s-21s. 2006
    ..Lastly, it provides group-wide education on pathology-related issues relevant to trial design, scientific study design, and specimen banking...
  5. ncbi request reprint Surgical pathology for the oncology patient in the age of standardization: of margins, micrometastasis, and molecular markers
    Carolyn C Compton
    Department of Pathology, McGill University Health Center, Montreal, Canada
    Semin Radiat Oncol 13:382-8. 2003
    ....
  6. ncbi request reprint Scoring of p53, VEGF, Bcl-2 and APAF-1 immunohistochemistry and interobserver reliability in colorectal cancer
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, QC, Canada
    Mod Pathol 19:1236-42. 2006
    ..In conclusion, p53 and VEGF protein expression assessed by immunohistochemistry in colorectal cancer and scored as a percentage of positive tumor cells may be a viable alternative scoring method...
  7. ncbi request reprint VEGF as a predictive marker of rectal tumor response to preoperative radiotherapy
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Cancer 104:2517-21. 2005
    ..The aim of this study was to determine whether VEGF expression in preirradiation tumor biopsies is a useful predictive marker of tumor response in patients with rectal cancer undergoing preoperative radiotherapy...
  8. ncbi request reprint The predictive value of apoptosis protease-activating factor 1 in rectal tumors treated with preoperative, high-dose-rate brachytherapy
    Inti Zlobec
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Cancer 106:284-6. 2006
    ..The objective of this study was to assess the value of apoptosis protease-activating factor 1 (APAF-1) as a predictive marker of response in rectal tumors treated with preoperative, high-dose-rate endorectal brachytherapy...
  9. pmc 2009 Biospecimen research network symposium: advancing cancer research through biospecimen science
    Helen M Moore
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 69:6770-2. 2009
    ..Biospecimen research represents the kind of bricks-and-mortar research that provides a solid scientific foundation for future advances that will directly help patients...
  10. ncbi request reprint Colorectal carcinoma: diagnostic, prognostic, and molecular features
    Carolyn C Compton
    Department of Pathology and University Health Center, McGill University, Montreal, Quebec
    Mod Pathol 16:376-88. 2003
    ..The need for high-quality, reproducible pathologic data in the care of the colorectal cancer patient, and the dependence of that data on standardization of all aspects of pathological assessment, is emphasized...
  11. pmc Custodianship as an ethical framework for biospecimen-based research
    Rihab Yassin
    Division of Cancer Biology, National Cancer Institute, 6130 Executive Boulevard, Suite 5000, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 19:1012-5. 2010
    ..Embracing the custodial model would ensure transparency in research, fairness to human research participants, and shared accountability among all stakeholders involved in biospecimen-based research...
  12. doi request reprint Protocol for the examination of specimens from patients with primary carcinomas of the colon and rectum
    Mary Kay Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232 2561, USA
    Arch Pathol Lab Med 132:1182-93. 2008
  13. ncbi request reprint A predictive model of rectal tumor response to preoperative radiotherapy using classification and regression tree methods
    Inti Zlobec
    Department of Pathology, McGill University Health Centre, Montreal, Quebec, Canada
    Clin Cancer Res 11:5440-3. 2005
    ....
  14. pmc International approaches to advancing biospecimen science
    Helen M Moore
    National Cancer Institute, Office of Biorepositories and Biospecimen Research, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 20:729-32. 2011
    ..A variety of efforts are under way around the world to establish research programs, evidence-based biospecimen protocols, and standards to improve the overall quality of biospecimens for research...
  15. doi request reprint Intersection of biobanking and clinical care: should discrepant diagnoses and pathological findings be returned to research participants?
    Nicole C Lockhart
    Office of Biorepositories and Biospecimen Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Genet Med 14:417-23. 2012
    ..Genet Med 2012:14(4):417-423...
  16. ncbi request reprint Protocol for the examination of specimens from patients with invasive carcinomas of the appendix
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:1433-9. 2006
  17. ncbi request reprint Protocol for the examination of specimens from patients with melanoma of the skin
    Carolyn C Compton
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Arch Pathol Lab Med 127:1253-62. 2003
  18. pmc Biospecimens and biorepositories: from afterthought to science
    Jimmie B Vaught
    Corresponding Author Jimmie B Vaught, Office of Biorepositories and Biospecimen Research, National Cancer Institute, 11400 Rockville Pike, Rockwall I, Suite 700, Bethesda, MD 20892
    Cancer Epidemiol Biomarkers Prev 21:253-5. 2012
    ..As the field matures, educating a new generation of biospecimen/biobanking scientists will be an important need. Cancer Epidemiol Biomarkers Prev; 21(2); 253-5. ©2012 AACR...
  19. ncbi request reprint Newer pathologic assessment techniques for colorectal carcinoma
    Roderick R Turner
    Department of Pathology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, USA
    Clin Cancer Res 13:6871s-6s. 2007
    ..This brief review discusses the most promising of these approaches and evidence supporting their potential clinical utility...
  20. pmc Tissue-based research in kidney cancer: current challenges and future directions
    Sabina Signoretti
    Department of Pathology, Brigham and Women s Hospital and Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Clin Cancer Res 14:3699-705. 2008
    ..In addition, some practical implementation strategies are proposed. Although many of the topics discussed are specific for renal cancer, several are also relevant to tissue based biomarker investigations in a broad array of malignancies...
  21. ncbi request reprint Pathologic prognostic factors in the recurrence of rectal cancer
    Carolyn C Compton
    Department of Pathology, McGill University, Montreal, Quebec, Canada
    Clin Colorectal Cancer 2:149-60. 2002
    ..The predictive value of tumor-specific molecular features is currently under investigation and may help to further improve prognostication and refine individual patient management in rectal cancer...
  22. doi request reprint AACR-FDA-NCI Cancer Biomarkers Collaborative consensus report: advancing the use of biomarkers in cancer drug development
    Samir N Khleif
    National Cancer Institute, Raritan, New Jersey, USA
    Clin Cancer Res 16:3299-318. 2010
    ....
  23. ncbi request reprint The staging of colorectal cancer: 2004 and beyond
    Carolyn C Compton
    Pathology, McGill University, Montreal, Canada
    CA Cancer J Clin 54:295-308. 2004
    ..For the tumor, node, metastasis system to remain relevant, it has to continuously undergo critical evaluation and change when clinically indicated...
  24. ncbi request reprint TNM residual tumor classification revisited
    Christian Wittekind
    Institute of Pathology, University Clinic of Leipzig, Leipzig, Germany
    Cancer 94:2511-6. 2002
    ..Despite the importance of residual tumor status in designing clinical management after treatment, misinterpretation and inconsistent application of the R classification frequently occur that diminish or abrogate its clinical utility...
  25. ncbi request reprint The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined
    Richard S Swanson
    National Cancer Data Base, American College of Surgeons, Chicago, Illinois, USA
    Ann Surg Oncol 10:65-71. 2003
    ..We examined data from the National Cancer Data Base (NCDB) to determine whether the number of examined lymph nodes is prognostic for T3N0 colon cancer...
  26. ncbi request reprint Histology of cystic tumors of the pancreas
    Carolyn C Compton
    Department of Pathology, McGill University, Office of the Chairman, 3775 University Street, Montreal, Quebec H3A 2B4, Canada
    Gastrointest Endosc Clin N Am 12:673-96. 2002
    ....
  27. doi request reprint Documenting biospecimen conditions in reports of studies
    James A Robb
    JAMA 300:650-1; author reply 651. 2008
  28. ncbi request reprint Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001
    Mark Redston
    Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 24:878-83. 2006
    ..To determine whether sentinel lymph node (LN) sampling (SLNS) could reduce the number of nodes required to characterize micrometastatic disease (MMD) in patients with potentially curable colon cancer...
  29. ncbi request reprint Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype
    Heather J Barker
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
    Cancer Lett 177:65-74. 2002
    ..These results indicate that GSTM1 genotype may not necessarily reflect GST mu phenotype in colorectal tumors...