C A Combs

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effect of muscle action and metabolic strain on oxidative metabolic responses in human skeletal muscle
    C A Combs
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Appl Physiol (1985) 87:1768-75. 1999
  2. pmc Direct imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP)
    C A Combs
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Biophys J 80:2018-28. 2001
  3. ncbi request reprint Two-photon excitation fluorescence pH detection using 2,3-dicyanohydroquinone: a spectral ratiometric approach
    P D Jobsis
    Laboratory of Cardiac Energetics, National Heart Lung and Blaood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Microsc 217:260-4. 2005
  4. pmc Compact non-contact total emission detection for in vivo multiphoton excitation microscopy
    C A Combs
    NHLBI Light Microscopy Facility, National Institutes of Health, Bethesda, Maryland, 20892 1623
    J Microsc 253:83-92. 2014

Collaborators

  • P D Jobsis
  • R S Balaban

Detail Information

Publications4

  1. ncbi request reprint Effect of muscle action and metabolic strain on oxidative metabolic responses in human skeletal muscle
    C A Combs
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Appl Physiol (1985) 87:1768-75. 1999
    ..Pooled data were found to more closely conform to previous biochemical measurements when a term for increasing oxidative capacity with metabolic strain was added to models of respiratory control...
  2. pmc Direct imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP)
    C A Combs
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Biophys J 80:2018-28. 2001
    ..These results suggest that ED-FRAP enables measurement of regional dynamics of mitochondrial NADH production in intact cells, thus providing information regarding region-specific intracellular redox reactions and energy metabolism...
  3. ncbi request reprint Two-photon excitation fluorescence pH detection using 2,3-dicyanohydroquinone: a spectral ratiometric approach
    P D Jobsis
    Laboratory of Cardiac Energetics, National Heart Lung and Blaood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Microsc 217:260-4. 2005
    ....
  4. pmc Compact non-contact total emission detection for in vivo multiphoton excitation microscopy
    C A Combs
    NHLBI Light Microscopy Facility, National Institutes of Health, Bethesda, Maryland, 20892 1623
    J Microsc 253:83-92. 2014
    ..The potential benefits of increased light collection in terms of speed of imaging and reduced photo-damage, as well as the applicability of this device to other multiphoton imaging methods is discussed. ..