Nelson B Cole

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Oxidative stress causes reversible changes in mitochondrial permeability and structure
    Nelson B Cole
    Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, Bethesda, MD 20892 8012, USA
    Exp Gerontol 45:596-602. 2010
  2. pmc Microtubule-dependent endosomal sorting of clathrin-independent cargo by Hook1
    Lymarie Maldonado-Baez
    Laboratory of Cell Biology, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Biol 201:233-47. 2013
  3. pmc Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification
    Nelson B Cole
    Genetic Diseases Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Exp Cell Res 314:2076-89. 2008
  4. pmc Pitstop 2 is a potent inhibitor of clathrin-independent endocytosis
    Dipannita Dutta
    Laboratory of Cell Biology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    PLoS ONE 7:e45799. 2012
  5. pmc Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A
    Geumsoo Kim
    Laboratory of Biochemistry, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 285:18085-94. 2010
  6. ncbi request reprint The cell biology of alpha-synuclein: a sticky problem?
    Nelson B Cole
    National Human Genome Research Institute NHGRI, Bethesda, MD 20892, USA
    Neuromolecular Med 1:95-109. 2002
  7. ncbi request reprint Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein
    Nelson B Cole
    Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health Bethesda, Maryland 20982, USA
    J Biol Chem 277:6344-52. 2002
  8. ncbi request reprint Structure and dynamics of micelle-bound human alpha-synuclein
    Tobias S Ulmer
    Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:9595-603. 2005
  9. ncbi request reprint Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments
    Nelson B Cole
    Genetic Diseases Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:9678-90. 2005
  10. pmc MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation
    Craig A Eyster
    Laboratory of Cell Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Biol Cell 22:3218-30. 2011

Collaborators

Detail Information

Publications11

  1. pmc Oxidative stress causes reversible changes in mitochondrial permeability and structure
    Nelson B Cole
    Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, Bethesda, MD 20892 8012, USA
    Exp Gerontol 45:596-602. 2010
    ..The ability of reactive oxygen species to reversibly alter the permeability of the mitochondrial membrane provides a potential mechanism for communication within the cell such as between nucleus and mitochondria...
  2. pmc Microtubule-dependent endosomal sorting of clathrin-independent cargo by Hook1
    Lymarie Maldonado-Baez
    Laboratory of Cell Biology, Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Biol 201:233-47. 2013
    ..Loss of Hook1 also led to an inhibition of cell spreading, implicating a role for Hook1 sorting of specific CIE cargo proteins away from bulk membrane and back to the PM...
  3. pmc Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification
    Nelson B Cole
    Genetic Diseases Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Exp Cell Res 314:2076-89. 2008
    ..These results imply a direct role for alpha-synuclein in mitochondrial physiology, especially under pathological conditions, and in principle, link alpha-synuclein to other PD genes in regulating mitochondrial homeostasis...
  4. pmc Pitstop 2 is a potent inhibitor of clathrin-independent endocytosis
    Dipannita Dutta
    Laboratory of Cell Biology, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    PLoS ONE 7:e45799. 2012
    ..Thus pitstop 2 has additional cellular targets besides the amino terminal domain of clathrin and thus cannot be used to distinguish CIE from CDE...
  5. pmc Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A
    Geumsoo Kim
    Laboratory of Biochemistry, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 285:18085-94. 2010
    ..Lipidation of methionine sulfoxide reductase A occurs in the mouse, in transfected tissue culture cells, and even in a cell-free protein synthesis system. The physiologic role of myristoylation of MsrA remains to be elucidated...
  6. ncbi request reprint The cell biology of alpha-synuclein: a sticky problem?
    Nelson B Cole
    National Human Genome Research Institute NHGRI, Bethesda, MD 20892, USA
    Neuromolecular Med 1:95-109. 2002
    ....
  7. ncbi request reprint Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein
    Nelson B Cole
    Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health Bethesda, Maryland 20982, USA
    J Biol Chem 277:6344-52. 2002
    ....
  8. ncbi request reprint Structure and dynamics of micelle-bound human alpha-synuclein
    Tobias S Ulmer
    Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:9595-603. 2005
    ....
  9. ncbi request reprint Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments
    Nelson B Cole
    Genetic Diseases Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 280:9678-90. 2005
    ....
  10. pmc MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation
    Craig A Eyster
    Laboratory of Cell Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Biol Cell 22:3218-30. 2011
    ..MARCH8 expression led to direct ubiquitination of CD98 and routing of CD98 to late endosomes/lysosomes...
  11. ncbi request reprint Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
    Deborah E Cabin
    Genetic Diseases Research Branch, National Human Genome Research Institute, Bethesda, Maryland 20892 4472, USA
    J Neurosci 22:8797-807. 2002
    ..These results reveal, for the first time, the normal function of endogenous alpha-synuclein in regulating synaptic vesicle mobilization at nerve terminals...