O J Cohen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Host factors in the pathogenesis of HIV disease
    O J Cohen
    National Institute of Allergy and Infectious Diseases, Laboratory of Immunoregulation, Bethesda, Maryland, USA
    Immunol Rev 159:31-48. 1997
  2. pmc CXCR4 and CCR5 genetic polymorphisms in long-term nonprogressive human immunodeficiency virus infection: lack of association with mutations other than CCR5-Delta32
    O J Cohen
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 1876, USA
    J Virol 72:6215-7. 1998
  3. ncbi request reprint Selection of HIV-specific immunogenic epitopes by screening random peptide libraries with HIV-1-positive sera
    G Scala
    Laboratory of Immunoregulation, and Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Immunol 162:6155-61. 1999
  4. pmc The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia
    G Pantaleo
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:254-8. 1997
  5. pmc Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection
    G Pantaleo
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:9848-53. 1997
  6. ncbi request reprint Peripheral blood-derived CD34+ progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV
    M E Ruiz
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1576, USA
    J Immunol 161:4169-76. 1998
  7. pmc HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells
    C Cicala
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 97:1178-83. 2000
  8. ncbi request reprint Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes
    X Chen
    Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA
    Nat Med 7:1225-31. 2001

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Host factors in the pathogenesis of HIV disease
    O J Cohen
    National Institute of Allergy and Infectious Diseases, Laboratory of Immunoregulation, Bethesda, Maryland, USA
    Immunol Rev 159:31-48. 1997
    ..HIV-specific immune responses, including cytotoxic T-lymphocyte (CTL) responses and neutralizing antibody responses, also appear to play salutary roles in protecting against disease progression...
  2. pmc CXCR4 and CCR5 genetic polymorphisms in long-term nonprogressive human immunodeficiency virus infection: lack of association with mutations other than CCR5-Delta32
    O J Cohen
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 1876, USA
    J Virol 72:6215-7. 1998
    ..Polymorphisms in the CXCR4 and CCR5 coding sequences other than CCR5-Delta32 do not appear to play a dominant mechanistic role in nonprogression among HIV-infected individuals...
  3. ncbi request reprint Selection of HIV-specific immunogenic epitopes by screening random peptide libraries with HIV-1-positive sera
    G Scala
    Laboratory of Immunoregulation, and Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Immunol 162:6155-61. 1999
    ..These results demonstrate that pools of HIV-1 mimotopes can be selected from combinatorial peptide libraries by taking advantage of the HIV-specific Ab repertoire induced by the natural infection...
  4. pmc The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia
    G Pantaleo
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:254-8. 1997
    ....
  5. pmc Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection
    G Pantaleo
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:9848-53. 1997
    ..These findings should provide insights into how HIV, and possibly other viruses, elude the host immune response during primary infection...
  6. ncbi request reprint Peripheral blood-derived CD34+ progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV
    M E Ruiz
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1576, USA
    J Immunol 161:4169-76. 1998
    ....
  7. pmc HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells
    C Cicala
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 97:1178-83. 2000
    ..En-velope treatment of lymphocytes led to the cleavage of FAK in a manner consistent with caspase-mediated cleavage...
  8. ncbi request reprint Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes
    X Chen
    Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA
    Nat Med 7:1225-31. 2001
    ..These results provide a new approach to the design of broadly protective HIV-1 vaccines...