Research Topics
| L X CleggSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Estimating average annual per cent change in trend analysisLimin X Clegg
Office of Inspector General, U S Department of Veterans Affairs, Washington, DC, USA
Stat Med 28:3670-82. 2009..The AAPC estimation has been incorporated into the segmented regression (free) software Joinpoint, which is used by many registries throughout the world for characterizing trends in cancer rates...
A marginal mixed baseline hazards model for multivariate failure time dataL X Clegg
National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7352, USA
Biometrics 55:805-12. 1999..Simulation studies indicate the adequacy of the proposed methodology for practical sample sizes. The methodology is illustrated with a data set from the Framingham Heart Study...
Impact of reporting delay and reporting error on cancer incidence rates and trendsLimin X Clegg
Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 94:1537-45. 2002..We studied the impact of reporting delay and reporting error on incidence rates and trends for cancers of the female breast, colorectal, lung/bronchus, prostate, and melanoma...
Comparison of self-reported initial treatment with medical records: results from the prostate cancer outcomes studyL X Clegg
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 8316, USA
Am J Epidemiol 154:582-7. 2001..These results can serve as a useful guide to researchers contemplating the use of surveys as an alternative to medical record abstraction to ascertain treatment in studies of patient outcomes...
Cancer survival among US whites and minorities: a SEER (Surveillance, Epidemiology, and End Results) Program population-based studyLimin X Clegg
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, 6116 Executive Blvd, MSC 8316, Suite 504, Bethesda, MD 20892 8316, USA
Arch Intern Med 162:1985-93. 2002....
Cancer surveillance series: interpreting trends in prostate cancer--part I: Evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival ratesB F Hankey
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 91:1017-24. 1999..Detailed data are presented for whites because the size of the population allows for calculating statistically reliable rates; however, similar overall trends are seen for African-Americans and other races...
Quality-of-life outcomes after primary androgen deprivation therapy: results from the Prostate Cancer Outcomes StudyA L Potosky
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
J Clin Oncol 19:3750-7. 2001..To compare health-related quality-of-life outcomes after primary androgen deprivation (AD) therapy with orchiectomy versus luteinizing hormone-releasing hormone (LHRH) agonists for patients with prostate cancer...
Partitioning linear trends in age-adjusted ratesB F Hankey
Cancer Statistics Branch, Cancer Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7352, USA
Cancer Causes Control 11:31-5. 2000..The objective here is to provide a method for partitioning a linear trend in age-adjusted rates into disease-specific components...
Lung disease mortality in the United States: the National Longitudinal Mortality StudyD R Lewis
Surveillance Research Program, National Cancer Institute, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland 20982 8316, USA
Int J Tuberc Lung Dis 13:1008-14. 2009..The National Longitudinal Mortality Study (NLMS) offers the advantage of assessing mortality in a representative population of the United States...
Projecting SEER cancer survival rates to the US: an ecological regression approachAngela Mariotto
Department of Epidemiology, Istituto Superiore di Sanita, Rome, Italy
Cancer Causes Control 13:101-11. 2002..The objective of this study is to project cancer survival for the entire US as well as states from survival data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program...
Community-based use of chemotherapy and hormonal therapy for early-stage breast cancer: 1987-2000Linda C Harlan
Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
J Clin Oncol 24:872-7. 2006..We describe trends in the use of chemotherapy and hormonal therapy by nodal and estrogen receptor (ER) status in women with early-stage breast cancer...
Estimating the variance of cancer prevalence from population-based registriesAnna Gigli
Istituto di Ricerche sulla Popolazione e le Politiche Sociali, Consiglio Nazionale delle Ricerche, Roma, Italy
Stat Methods Med Res 15:235-53. 2006..An analytic approach is considered to calculate the variance of step 3. A unified expression for the variance of the prevalence allowing for steps 1 through 3 is obtained. Some applications to cancer data are presented...
Patterns of care for adjuvant therapy in a random population-based sample of patients diagnosed with colorectal cancerDeirdre P Cronin
Surveillance Research Program, DCCPS, National Cancer Institute, Bethesda, Maryland, USA
Am J Gastroenterol 101:2308-18. 2006..Age disparities remain despite no evidence of greater chemotherapy-induced toxicity in the elderly. More equitable receipt of cancer treatment to all segments of the community will help to reduce mortality...
Rising incidence rates of breast carcinoma with micrometastatic lymph node involvementDeirdre P Cronin-Fenton
Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
J Natl Cancer Inst 99:1044-9. 2007..Increases in small tumors with micrometastatic lymph node involvement may be attributable to the increased use of the sentinel lymph node biopsy in community practice...
Patterns of care for cervical cancer patients treated in the U.S. military health care systemJohn H Farley
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, HI 96859 5000, USA
J Reprod Med 52:1040-5. 2007..S. Department of Defense (DOD) Military Health Care System received treatment within standard guidelines and whether survival was influenced by implementation of these guidelines...
Is mode of breast cancer detection associated with cancer treatment in the United States?K Robin Yabroff
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
Cancer 112:1011-9. 2008..In the current study, the authors explored whether detection by mammography was associated with greater use of guideline-consistent breast cancer treatment among patients with recently diagnosed breast cancer in the United States...
A new method to evaluate the completeness of case ascertainment by a cancer registryBarnali Das
Westat, 1650 Research Blvd, Rockville, MD, 20850, USA
Cancer Causes Control 19:515-25. 2008..NAACCR does not incorporate the variability of this index into the certification process...
Treatment and survival in a population-based sample of patients diagnosed with gastroesophageal adenocarcinomaDeirdre P Cronin-Fenton
Surveillance Research Program, DCCPS, National Cancer Institute, Bethesda MD 20892 7344, United States
World J Gastroenterol 14:3165-73. 2008..To examine the extent of use of specific therapies in clinical practice, and their relationship to therapies validated in clinical trials...
Insurance status and the use of guideline therapy in the treatment of selected cancersLinda C Harlan
Division of Cancer Control and Population Sciences, Cancer Therapy Evaluation Program, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 7344, USA
J Clin Oncol 23:9079-88. 2005..This study estimates the impact of type of insurance coverage on the receipt of guideline therapy in a population-based sample of cancer patients treated in the community...
Patterns of care in a population-based random sample of patients diagnosed with non-Hodgkin's lymphomaDeirdre P Cronin
National Cancer Registry Ireland, Elm Court, Boreenmanna Rd, Cork, Ireland
Hematol Oncol 23:73-81. 2005..01). This is the first population-based study examining therapy received for many histological subtypes of NHL...
Estimating the variance of disease-prevalence estimates from population-based registriesLimin X Clegg
National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 8316, USA
Biometrics 58:684-8. 2002..tend to have below-nominal coverage. For these reasons, we recommend the Poisson method, which also reduces the computational burden considerably...
Endocrine tumors of the uterine cervix: incidence, demographics, and survival with comparison to squamous cell carcinomaMargaret E McCusker
University of Maryland School of Medicine, Department of Epidemiology and Preventive Medicine, Baltimore, MD, USA
Gynecol Oncol 88:333-9. 2003..The aim was to describe the epidemiology of endocrine tumors of the cervix in comparison with invasive squamous cell carcinomas using population-based data reported to the Surveillance, Epidemiology and End-Results (SEER) program...
Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United StatesLinda C Harlan
National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Clin Oncol 21:3488-94. 2003..We examined patterns of care in a population-based sample of 601 ovarian cancer patients diagnosed in 1991, and a sample of 566 women was selected in 1996 to examine trends in care...
Epidemiology of primary Merkel cell carcinoma in the United StatesMaria Agelli
National Cancer Institute, Bethesda, MD, USA
J Am Acad Dermatol 49:832-41. 2003..Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer...
Chemotherapy in women with breast cancerLinda C Harlan
Ann Intern Med 139:868; author reply 868-9. 2003
Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survivalAhmedin Jemal
Epidemiology and Surveillance Research Department, American Cancer Society, 1599 Clifton Road, Atlanta, GA 30329, USA
Cancer 101:3-27. 2004..S. This year's report features a special section on cancer survival...
Pre-operative imaging, surgery and adjuvant therapy for women diagnosed with cancer of the corpus uteri in community practice in the United StatesEdward L Trimble
National Cancer Institute, Surgery Section, 6130 Executive Boulevard, Ste 741, M, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:741-8. 2005..Non-Hispanic black women are less often diagnosed with endometrial cancer than are non-Hispanic white women, but are more likely to die of their disease. Reasons for this disparity in outcome are not well understood...
Untreated cervical cancer in the United StatesEdward L Trimble
Surgery Section, National Cancer Institute, 6130 Executive Boulevard, Suite 741, MSC 7436, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:271-7. 2005..To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States...
Efficient interval estimation for age-adjusted cancer ratesRam C Tiwari
National Cancer Institute, NIH, Bethesda, MD, USA
Stat Methods Med Res 15:547-69. 2006..The proposed gamma and F intervals and the normal intervals for the correlated age-adjusted rates are recommended to be implemented in the Surveillance, Epidemiology and End Results Program of the National Cancer Institute...
Quality of race, Hispanic ethnicity, and immigrant status in population-based cancer registry data: implications for health disparity studiesLimin X Clegg
Office of Healthcare Inspections, Office of Inspector General, US Department of Veterans Affairs, Washington, DC 20001, USA
Cancer Causes Control 18:177-87. 2007..In particular, the study results caution against evaluating health disparities by using birthplace as a measure of immigrant status and race information for American Indians/Alaska Natives...
Quality of life following localized prostate cancer treated initially with androgen deprivation therapy or no therapyArnold L Potosky
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD
J Natl Cancer Inst 94:430-7. 2002..Therefore, men considering ADT as an initial treatment should be aware that sexual function and some aspects of physical well-being are likely to be affected in the first year following this treatment...
Primary malignant neoplasms of the appendix: a population-based study from the surveillance, epidemiology and end-results program, 1973-1998Margaret E McCusker
Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
Cancer 94:3307-12. 2002..Although several case series of these tumors have been published, little research has been anchored in population-based data on cancer of the appendix...
