Affiliation: National Institutes of Health
- Effect of cortisol on muscle sympathetic nerve activity in Pima Indians and CaucasiansBarbora Vozarova
Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Human Services, Phoenix, Arizona 85016, USA
J Clin Endocrinol Metab 88:3218-26. 2003..However, an acute release of cortisol is likely to more effectively contain sympathoexcitation during stress in Pima Indians than in Caucasians, which may be an important mechanism of cardioprotection in this Native American population...
- Treatment of obesity with extension of sleep duration: a randomized, prospective, controlled trialGiovanni Cizza
Clinical Endocrinology Section, Clinical Endocrinology Branch, NIDDK, USA
Clin Trials 7:274-85. 2010..The prevalence of chronic sleep deprivation is increasing in modern societies with negative health consequences. Recently, an association between short sleep and obesity has been reported...
- Do premenopausal women with major depression have low bone mineral density? A 36-month prospective studyGiovanni Cizza
Section on Neuroendocrinology of Obesity, National Institutes of Diabetes and Digestive Kidney Diseases NIDDK, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 7:e40894. 2012..An inverse relationship between major depressive disorder (MDD) and bone mineral density (BMD) has been suggested, but prospective evaluation in premenopausal women is lacking...
- Beyond fast food and slow motion: weighty contributors to the obesity epidemicG Cizza
Section on Neuroendocrinology of Obesity, NIDDK, Clinical Center, NIH, DHHS, Bethesda, MD, USA
J Endocrinol Invest 35:236-42. 2012..Surgical treatments, albeit effective in decreasing body weight, are invasive and expensive. Thus, our approaches to finding the causes, improving the existing treatments, and inventing novel therapies must be manifold...
- Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power studyGiovanni Cizza
Section on Neuroendocrinology of Obesity, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 7:e28912. 2012..The goal of the present study was to assess whether these clinical subtypes of depression have different endocrine and metabolic features and consequently, varying medical outcomes...
- Depression as a risk factor for osteoporosisGiovanni Cizza
Clinical Endocrine Section, Clinical Endocrinology Branch, NIDDK, NIH, DHHS, USA
Trends Endocrinol Metab 20:367-73. 2009..We propose that depression induces bone loss and osteoporotic fractures, primarily via specific immune and endocrine mechanisms, while poor lifestyle habits and use of specific antidepressants are potential contributory factors...
- Low 24-hour adiponectin and high nocturnal leptin concentrations in a case-control study of community-dwelling premenopausal women with major depressive disorder: the Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression (POWER) studyGiovanni Cizza
Clinical Endocrine Section, Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1613, USA
J Clin Psychiatry 71:1079-87. 2010....
- Major depressive disorder is a risk factor for low bone mass, central obesity, and other medical conditionsGiovanni Cizza
Diabetes, Obesity, Endocrine Branch, NIDDK, NIH, DHHS, Department of Laboratory Medicine, Clinical Center, Bethesda, Maryland 20892 1613, USA
Dialogues Clin Neurosci 13:73-87. 2011..It is proposed that depression induces bone loss and osteoporotic fractures, primarily via specific immune and endocrine mechanisms, with poor lifestyle habits as potential contributory factors...
- Chronic sleep deprivation and seasonality: implications for the obesity epidemicG Cizza
Section on Neuroendocrinology of Obesity, NIDDK, Bethesda, MD, USA
J Endocrinol Invest 34:793-800. 2011....
- Quality of life and pain in premenopausal women with major depressive disorder: the POWER StudyJill M Hartman
National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Health Qual Life Outcomes 4:2. 2006..4 +/- 6.6; mean +/- SD) and healthy matched controls (N = 36; age 35.4 +/- 6.4) participating in a study of bone turnover, the P.O.W.E.R. (Premenopausal, Osteopenia/Osteoporosis, Women, Alendronate, Depression) Study...
- Clinical manifestations of highly prevalent corticosteroid-binding globulin mutations in a village in southern ItalyGiovanni Cizza
National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 96:E1684-93. 2011..The largest kindred, exhibiting two mutations (null and Lyon) were Australian immigrants from Italy...
- Plasma CRP levels in premenopausal women with major depression: a 12-month controlled studyG Cizza
Clinical Endocrine Section, Clinical Endocrinology Branch, NIDDK, NIH, DHHS, Bethesda, MD 20892 1613, USA
Horm Metab Res 41:641-8. 2009..Depression was associated with increased plasma CRP in women with MDD. The clinical significance of abnormal plasma CRP for cardiovascular risk needs to be assessed in large prospective studies of women with depression...
- Depression and osteoporosis: a research synthesis with meta-analysisG Cizza
Clinical Endocrine Section, Clinical Endocrinology Branch, NIDDK, NIH, DHHS, Bethesda, MD, USA
Horm Metab Res 42:467-82. 2010..The deficits in bone mineral density in subjects with depression are of clinical significance and likely to increase fracture risk over the lifetime of these subjects...
- Elevated neuroimmune biomarkers in sweat patches and plasma of premenopausal women with major depressive disorder in remission: the POWER studyGiovanni Cizza
Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20852, USA
Biol Psychiatry 64:907-11. 2008..We used a skin sweat patch, recently validated in healthy control subjects, and recycling immunoaffinity chromatography to measure neuroimmune biomarkers in patients with MDD mostly in remission...
- [Brain-immune interactions and implications in psychiatric disorders]Andrea H Marques
Section on Neuroendocrine Immunology, National Institute of Mental Health, Integrative Neural Immune Program, Bethesda Rockville, Maryland 20852, USA
Rev Bras Psiquiatr 29:S27-32. 2007..This review will focus on the role of cytokines in the central nervous system and its implications to depressive disorder. We will then discuss the main findings of cytokine measurements in patients with major depressive disorder...
- Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individualsEliane A Lucassen
Clinical Center, National Institutes of Health, Bethesda, MD, USA
PLoS ONE 8:e56519. 2013..5 hours per night...
- Interacting epidemics? Sleep curtailment, insulin resistance, and obesityEliane A Lucassen
Immunogenetics Section, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
Ann N Y Acad Sci 1264:110-34. 2012....
- Maternal and environmental factors influence the hypothalamic-pituitary-adrenal axis response to corticotropin-releasing hormone infusion in offspring of mothers with or without mood disordersDonna S Ronsaville
NIMH, Bethesda, MD 20892-1277, USA
Dev Psychopathol 18:173-94. 2006..Our results add to the growing body of literature showing the influence of maternal characteristics and environmental factors on hypothalamic-pituitary-adrenal axis patterns in children...
- Effects of the physical work environment on physiological measures of stressJulian F Thayer
National Institute of Aging, National Institutes of Health, Baltimore, Maryland, USA
Eur J Cardiovasc Prev Rehabil 17:431-9. 2010..In this study we investigated the effects of the physical work environment on two physiological measures of the stress response...
- Bone mineral density in estrogen-deficient young womenVaishali B Popat
Intramural Research Program on Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1103, USA
J Clin Endocrinol Metab 94:2277-83. 2009..Osteoporosis primarily affects postmenopausal women. However, young women with estrogen deficiency also are at increased risk for low bone density...
- Poor sleep quality and sleep apnea are associated with higher resting energy expenditure in obese individuals with short sleep durationLilian De Jonge
Section on Neuroendocrinology of Obesity, Diabetes, Endocrinology, and Obesity Branch National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 2560, USA
J Clin Endocrinol Metab 97:2881-9. 2012..Epidemiological studies reported an inverse or U-shaped relationship between sleep duration and weight. The relationship between sleep and resting energy expenditure (REE) has not been well characterized...
- Measurement of cytokines in sweat patches and plasma in healthy women: validation in a controlled studyAndrea Marques-Deak
Section on Neuroendocrine Immunology and Behavior Integrative Neural Immune Program, NIMH, NIH, MSC-9401) Rockville, Maryland 20852, USA
J Immunol Methods 315:99-109. 2006..This approach can open a new generation of studies to address the effects of environmental factors on immune responses in a wide range of different settings...
- Behavioral, adrenal, and sympathetic responses to long-term administration of an oral corticotropin-releasing hormone receptor antagonist in a primate stress paradigmAlejandro R Ayala
Pediatric Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 89:5729-37. 2004..Taken together, these findings suggest that CRHR-1 antagonists may be a valid treatment for stress-related disorders...
- Testosterone suppression of CRH-stimulated cortisol in menDavid R Rubinow
Behavioral Endocrinology Branch, National Institute of Mental Health, Building 10 CRC, 10 Center Drive MSC 1276, Bethesda, MD 20892 1276, USA
Neuropsychopharmacology 30:1906-12. 2005..Our results further demonstrate that the enhanced stimulated HPA axis activity previously described in young men compared with young women cannot be ascribed to an activational upregulation of the axis by testosterone...
- The neuroendocrine system and rheumatoid arthritis: insights from anti-tumor necrosis factor-alpha therapyEsther M Sternberg
J Rheumatol 34:1443-5. 2007
- Low bone mass in premenopausal women with depressionFarideh Eskandari
Department of Medicine, Division of Clinical and Molecular Endocrinology, Case Western Reserve University, Cleveland, Ohio, USA
Arch Intern Med 167:2329-36. 2007..An increased prevalence of low bone mineral density (BMD) has been reported in patients with major depressive disorder (MDD), mostly women...
- Quantitative determination of antalarmin, a novel corticotropin-releasing hormone receptor-1 antagonist, in canine plasma by HPLC-MSStephen D Fox
Laboratory of Proteomics and Analytical Technologies, SAIC-Frederick, Inc, National Cancer Institute at Frederick, P.O. Box B, Frederick, MD 21702-1201, USA
J Sep Sci 28:332-6. 2005..Accuracy and precision variation for intra and inter-day validation were below the acceptable limit (15%) for pharmacokinetic studies...
- Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonistThomas L Horn
IIT Research Institute, Chicago, IL 60616, USA
Toxicology 248:8-17. 2008..The hepatic and renal toxicities seen in rats exposed to Antalarmin identify those tissues as the most likely targets for Antalarmin toxicity in humans...
- Cortisol response to ovine corticotropin-releasing hormone in a model of pregnancy and parturition in euthymic women with and without a history of postpartum depressionMiki Bloch
Department of Psychiatry, Tel-Aviv Sourasky Medical Center, Israel 64239
J Clin Endocrinol Metab 90:695-9. 2005....
- Younger, premenopausal women with major depressive disorder have more abdominal fat and increased serum levels of prothrombotic factors: implications for greater cardiovascular riskFarideh Eskandari
Department of Medicine, Division of Clinical and Molecular Endocrinology, Case Western Reserve University, Cleveland, OH 44106, USA
Metabolism 54:918-24. 2005....
- Efficacy of bisphosphonates for the control of alveolar bone loss in periodontitisMarjorie K Jeffcoat
University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA
J Int Acad Periodontol 9:70-6. 2007....