Kathryn H Ching

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bldg 49, 1C20, Bethesda, Maryland, 20892 4410, United States
    J Neuroimmunol 222:87-9. 2010
  2. pmc Salivary anti-Ro60 and anti-Ro52 antibody profiles to diagnose Sjogren's Syndrome
    K H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    J Dent Res 90:445-9. 2011
  3. pmc Antibody profiling of Borrelia burgdorferi infection in horses
    Peter D Burbelo
    National Institutes of Health, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 18:1562-7. 2011
  4. pmc Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Expert Rev Proteomics 8:309-16. 2011
  5. pmc Rapid serological detection of autoantibodies associated with Sjögren's syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Transl Med 7:83. 2009
  6. pmc LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Biosyst 7:1453-62. 2011
  7. pmc Antibody-profiling technologies for studying humoral responses to infectious agents
    Peter D Burbelo
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    Expert Rev Vaccines 9:567-78. 2010
  8. pmc Two major autoantibody clusters in systemic lupus erythematosus
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, Maryland, United States of America
    PLoS ONE 7:e32001. 2012
  9. pmc Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bethesda, MD 20892 4410, United States
    Neuromuscul Disord 21:204-13. 2011
  10. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010

Detail Information

Publications19

  1. pmc High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bldg 49, 1C20, Bethesda, Maryland, 20892 4410, United States
    J Neuroimmunol 222:87-9. 2010
    ..These results suggest the possibility that CNS autoimmunity may be responsible for the psychomotor impairment in this MDD patient...
  2. pmc Salivary anti-Ro60 and anti-Ro52 antibody profiles to diagnose Sjogren's Syndrome
    K H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    J Dent Res 90:445-9. 2011
    ..These results suggest that LIPS salivary-based testing for SjS autoantibodies is a practical alternative to serum and compatible with point-of-care testing...
  3. pmc Antibody profiling of Borrelia burgdorferi infection in horses
    Peter D Burbelo
    National Institutes of Health, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 18:1562-7. 2011
    ..These results suggest that LIPS tests employing multiple recombinant antigens offer a promising approach for the evaluation of antibody responses in Lyme disease...
  4. pmc Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Expert Rev Proteomics 8:309-16. 2011
    ....
  5. pmc Rapid serological detection of autoantibodies associated with Sjögren's syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Transl Med 7:83. 2009
    ..Here we investigated whether a quick version of luciferase immunoprecipitation systems (QLIPS) could be used to produce a rapid, specific and quantitative test to detect autoantibodies associated with SjS...
  6. pmc LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Biosyst 7:1453-62. 2011
    ..These results suggest that LIPS arrays offer a highly discriminating platform for simultaneously profiling a wide spectrum of antibodies associated with many infectious agents...
  7. pmc Antibody-profiling technologies for studying humoral responses to infectious agents
    Peter D Burbelo
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    Expert Rev Vaccines 9:567-78. 2010
    ..We also describe LIPS in detail and discuss several clinically relevant uses of the technology. Together, these new technologies offer new tools for understanding humoral responses to known and emerging infectious agents...
  8. pmc Two major autoantibody clusters in systemic lupus erythematosus
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, Maryland, United States of America
    PLoS ONE 7:e32001. 2012
    ....
  9. pmc Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bethesda, MD 20892 4410, United States
    Neuromuscul Disord 21:204-13. 2011
    ....
  10. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010
    ..This study was registered at http://clinicaltrials.gov as NCT00001355...
  11. pmc Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 201:1919-22. 2010
    ..These results suggest that antibody responses to lytic and latent KS-associated herpesvirus antigens differ in these diseases...
  12. pmc Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, 49 Convent Drive, Building 49, Room 1C20, NIDCR, NIH, Bethesda, MD 20892 4410, USA
    Clin Vaccine Immunol 17:904-9. 2010
    ..These results suggest that screening by the LIPS test with VOVO and other B. burgdorferi antigens offers an efficient quantitative approach for evaluation of the antibody responses in patients with Lyme disease...
  13. pmc Altered Antibody Profiles against Common Infectious Agents in Chronic Disease
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e81635. 2013
    ..The results suggest that antibody profiles against these and likely other common infectious agents may yield insight into the interplay between exposure to infectious agents, dysbiosis, adaptive immunity and disease activity. ..
  14. pmc Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 202:894-8. 2010
    ..These results suggest that profiling anti-HCV antibody is useful for monitoring HCV therapy, especially in discriminating between those who experience relapse and those who have SVRs at 48 weeks...
  15. pmc Emerging tactical strategies for fighting the war on cancer based on the genetic landscape
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, MD 20892, USA
    Am J Transl Res 3:251-8. 2011
    ..Capitalizing on these and other advances represent a new turning point in the war on cancer...
  16. pmc Rapid induction of autoantibodies during ARDS and septic shock
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Transl Med 8:97. 2010
    ....
  17. pmc Synthetic biology for translational research
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, MD 20892, USA
    Am J Transl Res 2:381-9. 2010
    ..Together these and other novel translational applications of artificial gene synthesis and synthetic biology have the opportunity to make major advances for improving human health...
  18. pmc Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e22576. 2011
    ..Together these results document human humoral responses to HMOAstV-C and validate LIPS as a facile and effective approach for identifying humoral responses to novel infectious agents...
  19. pmc Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Virol J 6:45. 2009
    ..Currently, there is a need for improved quantitative serological tests to document seropositivity with high sensitivity and specificity...