R S Chhabra

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Evaluation of some in vitro tests to reduce and replace the sub-acute animal toxicity studies
    Rajendra S Chhabra
    NIEHS, PO Box 12233, Research Triangle Park, NC 27709, USA
    Altern Lab Anim 32:137-40. 2004
  2. ncbi Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice
    R S Chhabra
    National Institute of Environmental Health Sciences, 111 Alexander Drive, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 60:28-37. 2001
  3. ncbi Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview
    Rajendra S Chhabra
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Int J Hyg Environ Health 206:437-45. 2003
  4. ncbi Carcinogenesis studies of cresols in rats and mice
    J M Sanders
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Toxicology 257:33-9. 2009
  5. ncbi Carcinogenesis studies of benzophenone in rats and mice
    M C Rhodes
    National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, United States
    Food Chem Toxicol 45:843-51. 2007
  6. ncbi Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice
    R S Chhabra
    Division of Toxicology Research and Testing, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Fundam Appl Toxicol 11:685-90. 1988
  7. ncbi Induction of micronucleated erythrocytes in rodents by diisopropylcarbodiimide and dicyclohexylcarbodiimide: dependence on exposure protocol
    K L Witt
    Integrated Laboratory Systems, Research Triangle Park, North Carolina 27709, USA
    Environ Mol Mutagen 33:65-74. 1999
  8. ncbi Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure
    Matthew D Stout
    Toxicology Operations Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicology 244:209-19. 2008
  9. ncbi Topical application of representative multifunctional acrylates produced proliferative and inflammatory lesions in F344/N rats and B6C3F1 mice, and squamous cell neoplasms in Tg.AC mice
    Adriana M Doi
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 33:631-40. 2005

Detail Information

Publications9

  1. ncbi Evaluation of some in vitro tests to reduce and replace the sub-acute animal toxicity studies
    Rajendra S Chhabra
    NIEHS, PO Box 12233, Research Triangle Park, NC 27709, USA
    Altern Lab Anim 32:137-40. 2004
    ..However, a larger comparative database is needed to derive definitive conclusions regarding the value of in vitro tests in the prediction of in vivo effects...
  2. ncbi Toxicology and carcinogenesis studies of p,p'-dichlorodiphenyl sulfone in rats and mice
    R S Chhabra
    National Institute of Environmental Health Sciences, 111 Alexander Drive, P O Box 12233, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 60:28-37. 2001
    ..A no-observed-adverse-effect level (NOAEL) of 30 ppm DDS in the diet (1.5 mg/kg body weight) was established for rats. DDS was not carcinogenic in these studies...
  3. ncbi Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview
    Rajendra S Chhabra
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Int J Hyg Environ Health 206:437-45. 2003
    ..These databases are available from the NTP web site (http://ntp-server.niehs.nih.gov) and are accessed over 100000 times a month from around the world...
  4. ncbi Carcinogenesis studies of cresols in rats and mice
    J M Sanders
    National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, United States
    Toxicology 257:33-9. 2009
    ..However, given the minimal chemical-related neoplastic response in these studies, it was concluded that there was no clear evidence of carcinogenicity in male rats or female mice exposed to the cresol mixture...
  5. ncbi Carcinogenesis studies of benzophenone in rats and mice
    M C Rhodes
    National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, United States
    Food Chem Toxicol 45:843-51. 2007
    ....
  6. ncbi Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice
    R S Chhabra
    Division of Toxicology Research and Testing, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Fundam Appl Toxicol 11:685-90. 1988
    ....
  7. ncbi Induction of micronucleated erythrocytes in rodents by diisopropylcarbodiimide and dicyclohexylcarbodiimide: dependence on exposure protocol
    K L Witt
    Integrated Laboratory Systems, Research Triangle Park, North Carolina 27709, USA
    Environ Mol Mutagen 33:65-74. 1999
    ..The data demonstrated a small but consistent induction of micronucleated erythrocytes in mice treated with DIC by skin painting...
  8. ncbi Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure
    Matthew D Stout
    Toxicology Operations Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Toxicology 244:209-19. 2008
    ..Hepatocellular adenomas, and adenoma or carcinoma (combined) were increased in male and female mice exposed to 1800ppm. There were also treatment-related increases in multiple adenomas in both sexes...
  9. ncbi Topical application of representative multifunctional acrylates produced proliferative and inflammatory lesions in F344/N rats and B6C3F1 mice, and squamous cell neoplasms in Tg.AC mice
    Adriana M Doi
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Pathol 33:631-40. 2005
    ..Although chronic inflammation might have contributed to the development of the skin lesions, the dose-related nature of the induction of the skin papillomas in Tg.AC mice by TMPTA and PETA may reflect a potential for carcinogenicity...