Bo Shiun Chen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Regulation of NMDA receptors by phosphorylation
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuropharmacology 53:362-8. 2007
  2. ncbi Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 62:471-8. 2009
  3. ncbi NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants
    Bo Shiun Chen
    Receptor Biology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:89-96. 2011
  4. ncbi Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 281:16583-90. 2006
  5. ncbi Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression
    Tina Tze Tsang Tang
    Receptor Biology Section, National Institute of Neurological Disorders and Stroke, Section on Neural Development and Plasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3714, USA
    Proc Natl Acad Sci U S A 106:21395-400. 2009
  6. ncbi SAP102 mediates synaptic clearance of NMDA receptors
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Cell Rep 2:1120-8. 2012

Collaborators

Detail Information

Publications6

  1. ncbi Regulation of NMDA receptors by phosphorylation
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuropharmacology 53:362-8. 2007
    ..Here we summarize recent advances in the characterization of NMDA receptor phosphorylation, emphasizing subunit-specific phosphorylation, which differentially controls the trafficking and surface expression of NMDA receptors...
  2. ncbi Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 62:471-8. 2009
    ..Finally, we find that NR2C expression, unlike NR2A and NR2B, supports neuronal survival. Thus, our data provide a direct mechanistic link between growth factor stimulation and regulation of cerebellar NMDA receptors...
  3. ncbi NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants
    Bo Shiun Chen
    Receptor Biology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:89-96. 2011
    ..Thus, our data provide the first evidence that SAP102 links NMDA receptor activation to alterations in spine morphology...
  4. ncbi Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 281:16583-90. 2006
    ....
  5. ncbi Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression
    Tina Tze Tsang Tang
    Receptor Biology Section, National Institute of Neurological Disorders and Stroke, Section on Neural Development and Plasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3714, USA
    Proc Natl Acad Sci U S A 106:21395-400. 2009
    ..These results reveal subunit-specific regulation of NMDARs by dysbindin, providing an unexpected link between these two proteins implicated in schizophrenia...
  6. ncbi SAP102 mediates synaptic clearance of NMDA receptors
    Bo Shiun Chen
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Cell Rep 2:1120-8. 2012
    ..These data reveal an unexpected, nonscaffolding role for SAP102 in the synaptic clearance of GluN2B-containing NMDARs...