Kenneth P Cantor

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populations
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, 8106 EPS, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Toxicol Appl Pharmacol 222:252-7. 2007
  2. pmc Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines: beta-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin, and hexachlorobenzene
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Environ Health Perspect 111:179-83. 2003
  3. ncbi request reprint Feasibility of conducting human studies to address bromate risks
    Kenneth P Cantor
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Plaza South, Bethesda, MD 20892, USA
    Toxicology 221:197-204. 2006
  4. pmc Polymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in Spain
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Environ Health Perspect 118:1545-50. 2010
  5. pmc A case-control study of tobacco use and other non-occupational risk factors for lymphoma subtypes defined by t(14; 18) translocations and bcl-2 expression
    Cindy M Chang
    Infections and Immunoepidemiology Branch, National Cancer Institute, Rockville, MD, USA
    Cancer Causes Control 21:1147-54. 2010
  6. pmc Bladder cancer and reproductive factors among women in Spain
    An Tsun Huang
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Cancer Causes Control 20:1907-13. 2009
  7. pmc Occupation and bladder cancer in a population-based case-control study in Northern New England
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7240, USA
    Occup Environ Med 68:239-49. 2011
  8. pmc Estimating water supply arsenic levels in the New England Bladder Cancer Study
    John R Nuckols
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1279-85. 2011
  9. ncbi request reprint Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokers
    Dominique S Michaud
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:853-9. 2004
  10. doi request reprint Does increased urination frequency protect against bladder cancer?
    Debra T Silverman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Cancer 123:1644-8. 2008

Detail Information

Publications45

  1. pmc Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populations
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, 8106 EPS, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Toxicol Appl Pharmacol 222:252-7. 2007
    ..Efforts are underway to improve exposure assessment in a large case-control study of bladder cancer in a region of the United States with moderately elevated levels of arsenic in drinking water...
  2. pmc Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines: beta-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin, and hexachlorobenzene
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Environ Health Perspect 111:179-83. 2003
    ..These findings do not support the hypothesis that the organochlorine compounds included in this study are strongly linked to the development of NHL. The possibility of a weak association cannot be excluded by these data...
  3. ncbi request reprint Feasibility of conducting human studies to address bromate risks
    Kenneth P Cantor
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Plaza South, Bethesda, MD 20892, USA
    Toxicology 221:197-204. 2006
    ..Such a study could fill an important data gap by providing human data to help estimate the carcinogenic risk from this exposure...
  4. pmc Polymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in Spain
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Environ Health Perspect 118:1545-50. 2010
    ..Bladder cancer has been linked with long-term exposure to disinfection by-products (DBPs) in drinking water...
  5. pmc A case-control study of tobacco use and other non-occupational risk factors for lymphoma subtypes defined by t(14; 18) translocations and bcl-2 expression
    Cindy M Chang
    Infections and Immunoepidemiology Branch, National Cancer Institute, Rockville, MD, USA
    Cancer Causes Control 21:1147-54. 2010
    ....
  6. pmc Bladder cancer and reproductive factors among women in Spain
    An Tsun Huang
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Cancer Causes Control 20:1907-13. 2009
    ..Women have a lower risk of bladder cancer than men, and hormonal factors related to childbearing may play a role...
  7. pmc Occupation and bladder cancer in a population-based case-control study in Northern New England
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7240, USA
    Occup Environ Med 68:239-49. 2011
    ..We used data from a large, population-based case-control study in Maine, New Hampshire, and Vermont to examine relationships between occupation, industry and bladder cancer risk...
  8. pmc Estimating water supply arsenic levels in the New England Bladder Cancer Study
    John R Nuckols
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Environ Health Perspect 119:1279-85. 2011
    ..Accurate retrospective exposure assessment over a long time period is a major challenge in conducting epidemiologic studies of environmental factors and diseases with long latency, such as cancer...
  9. ncbi request reprint Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokers
    Dominique S Michaud
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:853-9. 2004
    ..13, 95% confidence interval: 0.70, 1.81 for the highest vs. lowest quartile). These findings suggest that low-level arsenic exposure is unlikely to explain a substantial excess risk of bladder cancer...
  10. doi request reprint Does increased urination frequency protect against bladder cancer?
    Debra T Silverman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Cancer 123:1644-8. 2008
    ..Increased urination frequency, coupled with possible dilution of the urine from increased water intake, may diminish the effect of urinary carcinogens on bladder cancer risk...
  11. ncbi request reprint Non-Hodgkin's lymphoma among asthmatics exposed to pesticides
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Int J Cancer 111:298-302. 2004
    ..6 (1.0-2.4), respectively. Although there is limited power for assessing interaction, our results suggest that the risk of NHL among asthmatics with pesticide exposure may be higher than among nonasthmatics with pesticide exposure...
  12. ncbi request reprint Nitrate in public water supplies and the risk of renal cell carcinoma
    Mary H Ward
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
    Cancer Causes Control 18:1141-51. 2007
    ..These findings deserve additional study in populations with high water nitrate intake and information on dietary intakes...
  13. pmc A case-control study of smoking and bladder cancer risk: emergent patterns over time
    Dalsu Baris
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    J Natl Cancer Inst 101:1553-61. 2009
    ....
  14. ncbi request reprint Sampling private wells at past homes to estimate arsenic exposure: a methodologic study in New England
    Joanne S Colt
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    J Expo Anal Environ Epidemiol 12:329-34. 2002
    ..Various approaches for improving the success rates for sampling water from private wells are discussed, as is the use of predictive modeling to impute exposures when sampling is not feasible...
  15. doi request reprint Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New England
    Dalsu Baris
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, North Bethesda, MD 20852, USA
    Int J Cancer 132:162-73. 2013
    ..We observed a previously unrecognized risk associated with use of COX-2 inhibitors, which merits further evaluation...
  16. pmc Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentration
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Environ Health Perspect 116:1661-5. 2008
    ....
  17. ncbi request reprint Nitrate in public water supplies and risk of bladder cancer
    Mary H Ward
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Epidemiology 14:183-90. 2003
    ..Nitrate is a precursor compound in the formation of N-nitroso compounds, most of which are potent animal carcinogens. N-nitroso compounds and their precursors have not been extensively evaluated as bladder cancer risk factors...
  18. ncbi request reprint Nitrate in public water supplies and the risk of colon and rectum cancers
    Anneclaire J De Roos
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Epidemiology 14:640-9. 2003
    ..N-nitroso compound formation is inhibited by certain nutrients, such as vitamin C, and increased by meat intake...
  19. pmc Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and Vermont
    Petra Lenz
    Division of Cancer Epidemiology and Genetics, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD, USA
    Cancer Epidemiol Biomarkers Prev 21:1555-64. 2012
    ..Cell-cycle proteins are important predictive markers in urothelial carcinoma but may also exhibit exposure-specific heterogeneity...
  20. pmc Non-Hodgkin lymphoma (NHL) subtypes defined by common translocations: utility of fluorescence in situ hybridization (FISH) in a case-control study
    Cindy M Chang
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7074, Rockville, MD 20892, USA
    Leuk Res 34:190-5. 2010
    ..FISH assays detected twice as many t(14;18)-positive follicular lymphomas as PCR assays. Overall, study findings support the use of FISH assays to detect t(14;18) in archival tumor samples for epidemiologic studies of NHL subtypes...
  21. ncbi request reprint Hyperparathyroidism and subsequent cancer risk in Denmark
    Amy L PicKard
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Carrboro, North Carolina, USA
    Cancer 95:1611-7. 2002
    ..There is increasing evidence that hyperparathyroidism (HPT), a condition that leads to elevated serum calcium levels, is associated with endocrine and other malignancies, suggesting a possible causal link between HPT and carcinoma...
  22. pmc Exogenous and endogenous determinants of blood trihalomethane levels after showering
    Lorraine C Backer
    National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA
    Environ Health Perspect 116:57-63. 2008
    ..Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups...
  23. pmc Total fluid and water consumption and the joint effect of exposure to disinfection by-products on risk of bladder cancer
    Dominique S Michaud
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 115:1569-72. 2007
    ..A pooled analysis based on six case-control studies observed a positive association between tap water and bladder cancer but none for nontap fluid intake, suggesting that contaminants in tap water may be responsible for the excess risk...
  24. ncbi request reprint Parental occupational exposure to pesticides and the risk of childhood leukemia in Costa Rica
    Patricia Monge
    Central American Institute for Studies on Toxic Substances IRET, Universidad Nacional, PO Box 86 3000, Heredia, Costa Rica
    Scand J Work Environ Health 33:293-303. 2007
    ..Parental exposure to pesticides and the risk of leukemia in offspring were examined in a population-based case-control study in Costa Rica...
  25. ncbi request reprint Gender, alcohol consumption, and renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Epidemiol 155:455-62. 2002
    ..These findings suggest an inverse association of alcohol consumption and RCC development among women but not among men...
  26. ncbi request reprint Air pollution and risk of urinary bladder cancer in a case-control study in Spain
    Gemma Castano-Vinyals
    Gemma CastaƱo Vinyals, Centre for Research in Environmental Epidemiology CREAL, Municipal Institute of Medical Research, C Doctor Aiguader, 88, Barcelona 08003, Spain
    Occup Environ Med 65:56-60. 2008
    ..Air pollution has been associated with an increased risk for lung cancer. We examined whether long-term air pollution is associated with bladder cancer risk...
  27. ncbi request reprint Total and specific fluid consumption as determinants of bladder cancer risk
    Cristina M Villanueva
    Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    Int J Cancer 118:2040-7. 2006
    ..The association of bladder cancer with tap water consumption, but not with nontap water fluids, suggests that carcinogenic chemicals in tap water may explain the increased risk...
  28. ncbi request reprint Disinfection byproducts and bladder cancer: a pooled analysis
    Cristina M Villanueva
    Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    Epidemiology 15:357-67. 2004
    ..We pooled the primary data from 6 case-control studies of bladder cancer that used trihalomethanes as a marker of disinfection byproducts...
  29. ncbi request reprint Occupation and risk of pancreatic cancer: a population-based case-control study in iowa
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut 06520, USA
    J Occup Environ Med 47:392-8. 2005
    ..Previous epidemiological studies have inconsistently linked various occupations and industries to pancreatic cancer risk...
  30. ncbi request reprint Agricultural pesticide use, familial cancer, and risk of non-Hodgkin lymphoma
    Brian C H Chiu
    Department of Preventive Medicine and The Robert H Lurie Comprehensive Cancer Center, Northwestern University Medical School, 680 North Lake Shore Drive, Suite 1102, Chicago, IL 60611 4402, USA
    Cancer Epidemiol Biomarkers Prev 13:525-31. 2004
    ....
  31. ncbi request reprint A pooled analysis of bladder cancer case-control studies evaluating smoking in men and women
    Diana Puente
    Respiratory and Environmental Health Research Unit, Municipal Institute of Medical Research IMIM, 80 Dr Aiguader Rd, Barcelona, 08003, Spain
    Cancer Causes Control 17:71-9. 2006
    ..We pooled primary data from 14 case-control studies of bladder cancer from Europe and North America and evaluated differences in risk of smoking by gender...
  32. ncbi request reprint Pancreatic cancer and drinking water and dietary sources of nitrate and nitrite
    Angela Coss
    Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA
    Am J Epidemiol 159:693-701. 2004
    ....
  33. pmc Bladder cancer mortality and private well use in New England: an ecological study
    Joseph D Ayotte
    US Geological Survey, New Hampshire Vermont Water Science Center, Pembroke, USA
    J Epidemiol Community Health 60:168-72. 2006
    ..To investigate the possible relation between bladder cancer mortality among white men and women and private water use in New England, USA, where rates have been persistently raised and use of private water supplies (wells) common...
  34. ncbi request reprint Occupational and leisure-time physical activity and risk of colon cancer by subsite
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 48:236-43. 2006
    ..Studies of physical activity and colon cancer risk by anatomic site have provided inconsistent results...
  35. ncbi request reprint History of urinary tract infection and risk of renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 159:42-8. 2004
    ..Results suggest a positive association of UTI history with RCC development, with elevated risks most notable for males with a history of smoking...
  36. ncbi request reprint Modeling the probability of arsenic in groundwater in New England as a tool for exposure assessment
    Joseph D Ayotte
    U S Geological Survey NH VT Water Science Center, 361 Commerce Way, Pembroke, New Hampshire 03275, USA
    Environ Sci Technol 40:3578-85. 2006
    ..Due to the complexity of the fractured bedrock aquifers in the region, well depth and related variables also are not significant predictors...
  37. ncbi request reprint A population-based case-control study of occupation and renal cell carcinoma risk in Iowa
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 46:235-40. 2004
    ..1-11.3); colleges and universities (OR 7.6-95% CI = 2.3-25.6); and retail, including those in grocery stores (OR 2.2, 95% CI = 1.0-4.7). Our results indicate that occupational exposures may increase the risk of renal cell carcinoma...
  38. ncbi request reprint Smoking cessation and renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Ann Epidemiol 13:245-51. 2003
    ..Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the inverse correlation of cessation years with lifetime smoking exposure...
  39. ncbi request reprint Occupation and bladder cancer: a population-based, case-control study in Iowa
    Tongzhang Zheng
    Division of Environmental Health Science, Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 44:685-91. 2002
    ..Housekeepers and butlers and workers in laundering and dry cleaning were also at increased risk. In conclusion, these results suggest that occupational exposures may play a significant role in the risk of bladder cancer...
  40. ncbi request reprint Inorganic arsenic in drinking water: an evolving public health concern
    Jay H Lubin
    J Natl Cancer Inst 99:906-7. 2007
  41. pmc Disinfection byproducts in drinking water and skin cancer? A hypothesis
    Margaret R Karagas
    Cancer Causes Control 19:547-8. 2008
  42. ncbi request reprint Bulky DNA adduct formation and risk of bladder cancer
    Gemma Castano-Vinyals
    Centre for Research in Environmental Epidemiology, Institut Municipal d Investigacio Medica, Doctor Aiguader, 88, 08003 Barcelona, Spain
    Cancer Epidemiol Biomarkers Prev 16:2155-9. 2007
    ..Results do not support an association of bladder cancer risk with low-level exposure to PAHs as measured through the formation of bulky DNA adducts in peripheral mononuclear cells...
  43. ncbi request reprint Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools
    Cristina M Villanueva
    Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain
    Am J Epidemiol 165:148-56. 2007
    ..57 (95% confidence interval: 1.18, 2.09). Bladder cancer risk was associated with long-term exposure to THMs in chlorinated water at levels regularly occurring in industrialized countries...
  44. ncbi request reprint Polychlorinated biphenyl levels in peripheral blood and non-Hodgkin's lymphoma: a report from three cohorts
    Lawrence S Engel
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 67:5545-52. 2007
    ..The results from these three cohorts suggest that concentrations of certain PCBs in blood are associated with increased risk of NHL...
  45. ncbi request reprint Alcohol consumption, family history of hematolymphoproliferative cancer, and the risk of non-Hodgkin's lymphoma in men
    Brian C H Chiu
    Department of Preventive and Societal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 4350, USA
    Ann Epidemiol 12:309-15. 2002
    ..To investigate the association between alcohol consumption and the risk of non-Hodgkin's lymphoma (NHL) and to examine whether the association is modified by a family history of hematolymphoproliferative cancer (HLPC)...