Research Topics
Species | Kenneth P CantorSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populationsKenneth P Cantor
Division of Cancer Epidemiology and Genetics, 8106 EPS, National Cancer Institute, Bethesda, MD 20892 7240, USA
Toxicol Appl Pharmacol 222:252-7. 2007..Efforts are underway to improve exposure assessment in a large case-control study of bladder cancer in a region of the United States with moderately elevated levels of arsenic in drinking water...
Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines: beta-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin, and hexachlorobenzeneKenneth P Cantor
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
Environ Health Perspect 111:179-83. 2003..These findings do not support the hypothesis that the organochlorine compounds included in this study are strongly linked to the development of NHL. The possibility of a weak association cannot be excluded by these data...
Feasibility of conducting human studies to address bromate risksKenneth P Cantor
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Plaza South, Bethesda, MD 20892, USA
Toxicology 221:197-204. 2006..Such a study could fill an important data gap by providing human data to help estimate the carcinogenic risk from this exposure...
Polymorphisms in GSTT1, GSTZ1, and CYP2E1, disinfection by-products, and risk of bladder cancer in SpainKenneth P Cantor
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
Environ Health Perspect 118:1545-50. 2010..Bladder cancer has been linked with long-term exposure to disinfection by-products (DBPs) in drinking water...
A case-control study of tobacco use and other non-occupational risk factors for lymphoma subtypes defined by t(14; 18) translocations and bcl-2 expressionCindy M Chang
Infections and Immunoepidemiology Branch, National Cancer Institute, Rockville, MD, USA
Cancer Causes Control 21:1147-54. 2010....
Bladder cancer and reproductive factors among women in SpainAn Tsun Huang
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Cancer Causes Control 20:1907-13. 2009..Women have a lower risk of bladder cancer than men, and hormonal factors related to childbearing may play a role...
Occupation and bladder cancer in a population-based case-control study in Northern New EnglandJoanne S Colt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7240, USA
Occup Environ Med 68:239-49. 2011..We used data from a large, population-based case-control study in Maine, New Hampshire, and Vermont to examine relationships between occupation, industry and bladder cancer risk...
Estimating water supply arsenic levels in the New England Bladder Cancer StudyJohn R Nuckols
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Environ Health Perspect 119:1279-85. 2011..Accurate retrospective exposure assessment over a long time period is a major challenge in conducting epidemiologic studies of environmental factors and diseases with long latency, such as cancer...
Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokersDominique S Michaud
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Am J Epidemiol 160:853-9. 2004..13, 95% confidence interval: 0.70, 1.81 for the highest vs. lowest quartile). These findings suggest that low-level arsenic exposure is unlikely to explain a substantial excess risk of bladder cancer...
Does increased urination frequency protect against bladder cancer?Debra T Silverman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 123:1644-8. 2008..Increased urination frequency, coupled with possible dilution of the urine from increased water intake, may diminish the effect of urinary carcinogens on bladder cancer risk...
Non-Hodgkin's lymphoma among asthmatics exposed to pesticidesWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Int J Cancer 111:298-302. 2004..6 (1.0-2.4), respectively. Although there is limited power for assessing interaction, our results suggest that the risk of NHL among asthmatics with pesticide exposure may be higher than among nonasthmatics with pesticide exposure...
Nitrate in public water supplies and the risk of renal cell carcinomaMary H Ward
Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
Cancer Causes Control 18:1141-51. 2007..These findings deserve additional study in populations with high water nitrate intake and information on dietary intakes...
A case-control study of smoking and bladder cancer risk: emergent patterns over timeDalsu Baris
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
J Natl Cancer Inst 101:1553-61. 2009....
Sampling private wells at past homes to estimate arsenic exposure: a methodologic study in New EnglandJoanne S Colt
Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
J Expo Anal Environ Epidemiol 12:329-34. 2002..Various approaches for improving the success rates for sampling water from private wells are discussed, as is the use of predictive modeling to impute exposures when sampling is not feasible...
Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New EnglandDalsu Baris
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, North Bethesda, MD 20852, USA
Int J Cancer 132:162-73. 2013..We observed a previously unrecognized risk associated with use of COX-2 inhibitors, which merits further evaluation...
Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentrationJay H Lubin
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
Environ Health Perspect 116:1661-5. 2008....
Nitrate in public water supplies and risk of bladder cancerMary H Ward
Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
Epidemiology 14:183-90. 2003..Nitrate is a precursor compound in the formation of N-nitroso compounds, most of which are potent animal carcinogens. N-nitroso compounds and their precursors have not been extensively evaluated as bladder cancer risk factors...
Nitrate in public water supplies and the risk of colon and rectum cancersAnneclaire J De Roos
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Epidemiology 14:640-9. 2003..N-nitroso compound formation is inhibited by certain nutrients, such as vitamin C, and increased by meat intake...
Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and VermontPetra Lenz
Division of Cancer Epidemiology and Genetics, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD, USA
Cancer Epidemiol Biomarkers Prev 21:1555-64. 2012..Cell-cycle proteins are important predictive markers in urothelial carcinoma but may also exhibit exposure-specific heterogeneity...
Non-Hodgkin lymphoma (NHL) subtypes defined by common translocations: utility of fluorescence in situ hybridization (FISH) in a case-control studyCindy M Chang
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7074, Rockville, MD 20892, USA
Leuk Res 34:190-5. 2010..FISH assays detected twice as many t(14;18)-positive follicular lymphomas as PCR assays. Overall, study findings support the use of FISH assays to detect t(14;18) in archival tumor samples for epidemiologic studies of NHL subtypes...
Hyperparathyroidism and subsequent cancer risk in DenmarkAmy L PicKard
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Carrboro, North Carolina, USA
Cancer 95:1611-7. 2002..19; 95%CI, 4.3-61.9; based on 3 patients). CONCLUSIONS: Future studies should monitor whether specific endocrine alterations associated with HPT may affect the long-term risk of hematopoetic, thyroid, and urinary tract carcinomas...
Exogenous and endogenous determinants of blood trihalomethane levels after showeringLorraine C Backer
National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA
Environ Health Perspect 116:57-63. 2008..Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups...
Total fluid and water consumption and the joint effect of exposure to disinfection by-products on risk of bladder cancerDominique S Michaud
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Environ Health Perspect 115:1569-72. 2007..A pooled analysis based on six case-control studies observed a positive association between tap water and bladder cancer but none for nontap fluid intake, suggesting that contaminants in tap water may be responsible for the excess risk...
Parental occupational exposure to pesticides and the risk of childhood leukemia in Costa RicaPatricia Monge
Central American Institute for Studies on Toxic Substances IRET, Universidad Nacional, PO Box 86 3000, Heredia, Costa Rica
Scand J Work Environ Health 33:293-303. 2007..Parental exposure to pesticides and the risk of leukemia in offspring were examined in a population-based case-control study in Costa Rica...
Gender, alcohol consumption, and renal cell carcinomaAlexander S Parker
Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Am J Epidemiol 155:455-62. 2002..These findings suggest an inverse association of alcohol consumption and RCC development among women but not among men...
Air pollution and risk of urinary bladder cancer in a case-control study in SpainGemma Castano-Vinyals
Gemma CastaƱo Vinyals, Centre for Research in Environmental Epidemiology CREAL, Municipal Institute of Medical Research, C Doctor Aiguader, 88, Barcelona 08003, Spain
Occup Environ Med 65:56-60. 2008..Air pollution has been associated with an increased risk for lung cancer. We examined whether long-term air pollution is associated with bladder cancer risk...
Total and specific fluid consumption as determinants of bladder cancer riskCristina M Villanueva
Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
Int J Cancer 118:2040-7. 2006..The association of bladder cancer with tap water consumption, but not with nontap water fluids, suggests that carcinogenic chemicals in tap water may explain the increased risk...
Disinfection byproducts and bladder cancer: a pooled analysisCristina M Villanueva
Respiratory and Environmental Health Research Unit, , Barcelona, Spain
Epidemiology 15:357-67. 2004..95; 0.76-1.20). CONCLUSIONS: These findings strengthen the hypothesis that the risk of bladder cancer is increased with long-term exposure to disinfection byproducts at levels currently observed in many industrialized countries...
Occupation and risk of pancreatic cancer: a population-based case-control study in iowaYawei Zhang
Yale University School of Public Health, New Haven, Connecticut 06520, USA
J Occup Environ Med 47:392-8. 2005..Previous epidemiological studies have inconsistently linked various occupations and industries to pancreatic cancer risk...
Agricultural pesticide use, familial cancer, and risk of non-Hodgkin lymphomaBrian C H Chiu
Department of Preventive Medicine and The Robert H Lurie Comprehensive Cancer Center, Northwestern University Medical School, 680 North Lake Shore Drive, Suite 1102, Chicago, IL 60611 4402, USA
Cancer Epidemiol Biomarkers Prev 13:525-31. 2004....
A pooled analysis of bladder cancer case-control studies evaluating smoking in men and womenDiana Puente
Respiratory and Environmental Health Research Unit, Municipal Institute of Medical Research (IMIM, 80 Dr Aiguader Rd, Barcelona, 08003, Spain
Cancer Causes Control 17:71-9. 2006..CONCLUSION: These results do not support the hypothesis that women have a higher relative risk of smoking-related bladder cancer than men...
Pancreatic cancer and drinking water and dietary sources of nitrate and nitriteAngela Coss
Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA
Am J Epidemiol 159:693-701. 2004....
Bladder cancer mortality and private well use in New England: an ecological studyJoseph D Ayotte
US Geological Survey, New Hampshire-Vermont Water Science Center, Pembroke, USA
J Epidemiol Community Health 60:168-72. 2006..Analytical studies are underway to clarify the relation between suspected water contaminants, particularly arsenic, and raised bladder cancer rates in northern New England...
Occupational and leisure-time physical activity and risk of colon cancer by subsiteYawei Zhang
Yale University School of Public Health, New Haven, Connecticut, USA
J Occup Environ Med 48:236-43. 2006..5; 95% confidence interval, 0.3-0.8). CONCLUSIONS: Increased physical activity was inversely associated with colon cancer risk. The inverse associations were stronger for the right than for the left colon...
History of urinary tract infection and risk of renal cell carcinomaAlexander S Parker
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
Am J Epidemiol 159:42-8. 2004..Results suggest a positive association of UTI history with RCC development, with elevated risks most notable for males with a history of smoking...
Modeling the probability of arsenic in groundwater in New England as a tool for exposure assessmentJoseph D Ayotte
U S Geological Survey NH VT Water Science Center, 361 Commerce Way, Pembroke, New Hampshire 03275, USA
Environ Sci Technol 40:3578-85. 2006..Due to the complexity of the fractured bedrock aquifers in the region, well depth and related variables also are not significant predictors...
A population-based case-control study of occupation and renal cell carcinoma risk in IowaYawei Zhang
Yale University School of Public Health, New Haven, Connecticut, USA
J Occup Environ Med 46:235-40. 2004..1-11.3); colleges and universities (OR 7.6-95% CI = 2.3-25.6); and retail, including those in grocery stores (OR 2.2, 95% CI = 1.0-4.7). Our results indicate that occupational exposures may increase the risk of renal cell carcinoma...
Smoking cessation and renal cell carcinomaAlexander S Parker
Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Ann Epidemiol 13:245-51. 2003..Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the inverse correlation of cessation years with lifetime smoking exposure...
Occupation and bladder cancer: a population-based, case-control study in IowaTongzhang Zheng
Division of Environmental Health Science, Yale University School of Public Health, New Haven, Connecticut, USA
J Occup Environ Med 44:685-91. 2002..Housekeepers and butlers and workers in laundering and dry cleaning were also at increased risk. In conclusion, these results suggest that occupational exposures may play a significant role in the risk of bladder cancer...
Inorganic arsenic in drinking water: an evolving public health concernJay H Lubin
J Natl Cancer Inst 99:906-7. 2007
Disinfection byproducts in drinking water and skin cancer? A hypothesisMargaret R Karagas
Cancer Causes Control 19:547-8. 2008
Bulky DNA adduct formation and risk of bladder cancerGemma Castano-Vinyals
Centre for Research in Environmental Epidemiology, Institut Municipal d Investigacio Medica, Doctor Aiguader, 88, 08003 Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 16:2155-9. 2007..Results do not support an association of bladder cancer risk with low-level exposure to PAHs as measured through the formation of bulky DNA adducts in peripheral mononuclear cells...
Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in poolsCristina M Villanueva
Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain
Am J Epidemiol 165:148-56. 2007..57 (95% confidence interval: 1.18, 2.09). Bladder cancer risk was associated with long-term exposure to THMs in chlorinated water at levels regularly occurring in industrialized countries...
Polychlorinated biphenyl levels in peripheral blood and non-Hodgkin's lymphoma: a report from three cohortsLawrence S Engel
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer Res 67:5545-52. 2007..The results from these three cohorts suggest that concentrations of certain PCBs in blood are associated with increased risk of NHL...
Alcohol consumption, family history of hematolymphoproliferative cancer, and the risk of non-Hodgkin's lymphoma in menBrian C-H Chiu
Department of Preventive and Societal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-4350, USA
Ann Epidemiol 12:309-15. 2002..The finding of effect modification of the alcohol-NHL association by a family history of HLPC is novel and requires confirmation...
