Research Topics
Species | Katherine R CalvoSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Clinical proteomics: from biomarker discovery and cell signaling profiles to individualized personal therapyKatherine R Calvo
Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Biosci Rep 25:107-25. 2005....
IL-4 protein expression and basal activation of Erk in vivo in follicular lymphomaKatherine R Calvo
Hematopathology Section, Laboratory of Pathology LP, NIH Clinical Center, Department of Laboratory Medicine, 10 Center Drive, Bldg 10 2C306, Bethesda, MD 20892 1500, USA
Blood 112:3818-26. 2008..These findings suggest IL-4, Erk, and possibly Stat-6 may play a role in the biology of FL and may serve as targets for future therapies...
Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implicationsKatherine R Calvo
Hematology Section, Department of Laboratory Medicine, NIH Clinical Center, 10 Center Dr, Bethesda, MD 20892 1508, USA
Haematologica 96:1221-5. 2011..MonoMAC appears to be a unique, inherited syndrome of bone marrow failure. We describe distinctive bone marrow features to help in its recognition and diagnosis. (Clinicaltrials.gov identifiers: NCT00018044, NCT00923364, NCT01212055)...
MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor responseWeixin Wang
Department of Laboratory Medicine, Hematology Section NIH Clinical Center, 10 Center Dr, Bldg 10 2C306 Bethesda, 20892 1508, USA
Haematologica 97:586-94. 2012..MicroRNAs can play an important role in tumorigenesis through post-transcriptional regulation of gene expression, and are not well characterized in follicular lymphoma...
Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancerFrancisco G Pernas
Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Clin Cancer Res 15:2361-72. 2009..To investigate the underlying molecular mechanism, the proteomic signatures and responses of EGFR and downstream signals have been studied in a panel of HNSCC cell lines and tumor specimens pre- and post-gefitinib treatment...
Both variant and IGHV4-34-expressing hairy cell leukemia lack the BRAF V600E mutationLiqiang Xi
Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Blood 119:3330-2. 2012..Our results suggest that HCLv and IGHV4-34(+) HCLs have a different pathogenesis than HCLc and that a significant minority of other HCLc are also wild-type for BRAF V600...
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndromeAmy P Hsu
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bethesda, MD 20892 1684, USA
Blood 118:2653-5. 2011..Thus, GATA2 joins RUNX1 and CEBPA not only as a familial leukemia gene but also as a cause of a complex congenital immunodeficiency that evolves over decades and combines predisposition to infection and myeloid malignancy...
Role of microRNAs from monoclonal gammopathy of undetermined significance to multiple myelomaKatherine R Calvo
Hematology Section, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD
Semin Hematol 48:39-45. 2011....
Flow cytometry immunophenotyping of hematolymphoid neoplasiaKatherine R Calvo
Department of Laboratory Medicine, Hematology Section, National Institutes of Health Clinical Center, Bethesda, MD, USA
Methods Mol Biol 699:295-316. 2011..In this chapter, we present a general approach to analyze hematolymphoid populations. Specimen handling, gating strategies, and appropriate antibody panels for flow cytometric detection of abnormal hematologic populations are presented...
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8Gang G Wang
Department of Pathology and Molecular Pathology Graduate Program, School of Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Nat Methods 3:287-93. 2006..Using knockout or small interfering RNA (siRNA) technologies, this ER-Hoxb8 phagocyte maturation system represents a rapid analytical tool for studying macrophage and neutrophil biology...
Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1Katherine R Calvo
University of California School of Medicine, Department of Pathology 9500 Gilman Drive, La Jolla, California, CA 92093 0612, USA
Oncogene 21:4247-56. 2002..Rapid leukaemogenesis by Nup98-HoxA9 may therefore result from both the intrinsic functions of Nup98-HoxA9, as well as of those of coexpressed HOX and MEIS1 genes...
