Research Topics
Species | Denis B BuxtonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Calcium-dependent threonine phosphorylation of nonmuscle myosin in stimulated RBL-2H3 mast cellsD B Buxton
Laboratory of Molecular Cardiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 275:34772-9. 2000..These data indicate a role for CaM kinase stimulation and resultant threonine phosphorylation of NMHC-IIA in RBL-2H3 m1 cell activation...
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophagesDenis B Buxton
Laboratory of Molecular Cardiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 278:15449-55. 2003..8-Bromo-cGMP had no effect on nonmuscle myosin heavy chain induction, consistent with a cGMP-independent mechanism for nitric oxide-mediated inhibition of nonmuscle myosin heavy chain II-C induction...
Recommendations of the National Heart, Lung, and Blood Institute Nanotechnology Working GroupDenis B Buxton
Division of Heart and Vascular Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
Circulation 108:2737-42. 2003..Finally, encouragement of small businesses to develop nanotechnology-based approaches to clinical problems was considered important...
Nanotechnology in the diagnosis and management of heart, lung and blood diseasesDenis B Buxton
National Heart, Lung, and Blood Institute, Advanced Technologies and Surgery Branch, Division of Cardiovascular Diseases, Bethesda, MD 20892, USA
Expert Rev Mol Diagn 7:149-60. 2007..The goal is to summarize the current state of science and technology in these areas and to look at future directions that the field is likely to move in to enhance the diagnosis and treatment of heart, lung and blood diseases...
Nanomedicine for the management of lung and blood diseasesDenis B Buxton
Advanced Technologies and Surgery Branch, Division of Cardiovascular Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA
Nanomedicine (Lond) 4:331-9. 2009..Treatment of both lung and blood diseases is also likely to benefit from nano-scaffold-based methods for controlling the differentiation and proliferation of stem and progenitor cells...
Current status of nanotechnology approaches for cardiovascular disease: a personal perspectiveDenis B Buxton
National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Bethesda, MD 20892 7940, USA
Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:149-55. 2009..Taken together, these new technologies have enormous potential for improving the diagnosis and treatment of cardiovascular diseases...
A single class II myosin modulates T cell motility and stopping, but not synapse formationJordan Jacobelli
Department of Pathology, University of California at San Francisco, 513 Parnassus Ave, San Francisco, California 93143, USA
Nat Immunol 5:531-8. 2004..Phosphorylation of MyH9 in its multimerization domain by T cell receptor-generated signals indicates that inactivation of this motor may be a key step in the 'stop' response during antigen recognition...
