Research Topics
Genomes and Genes
| Shawn M BurgessSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
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Detail Information
Publications
The zebrafish gene claudinj is essential for normal ear function and important for the formation of the otolithsAmanda L Hardison
Genome Technology Branch, National Human Genome Research Institute, NIH, Building 50, Room 5537, 50 South Drive, Bethesda, MD 20892 8004, USA
Mech Dev 122:949-58. 2005....
Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafishViviana E Gallardo
Center for Genome Regulation Facultad de Ciencias, Universidad de Chile, Casilla 653 Santiago, Chile
BMC Dev Biol 10:120. 2010..Therefore the primordium provides both a model for studying collective directional cell migration and the differentiation of sensory cells from multipotent progenitor cells...
Using retroviruses as a mutagenesis tool to explore the zebrafish genomeLi En Jao
Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Brief Funct Genomic Proteomic 7:427-43. 2008..Lastly, we point to some potential directions that retroviral mutagenesis might take from the lessons of studying other model organisms...
The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafish stat3/socs3a pathway: regulator of hair cell regenerationJin Liang
Genome Technology Branch, and Inherited Disease Research Branch, National Human Genome Research Institute, Bethesda, Maryland 20892, USA
J Neurosci 32:10662-73. 2012..2008; Zhu et al., 2008; Qin et al., 2009), we propose that the stat3/socs3 pathway is a key response in all tissue regeneration and thus an important therapeutic target for a broad application in tissue repair and injury healing...
Transcriptional signature of accessory cells in the lateral line, using the Tnk1bp1:EGFP transgenic zebrafish lineMartine Behra
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
BMC Dev Biol 12:6. 2012..However, the lack of regenerative capacity in mammals is the single leading cause for acquired hearing disorders in humans...
Disruption of the folate pathway in zebrafish causes developmental defectsMarina S Lee
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
BMC Dev Biol 12:12. 2012..The biological mechanisms through which folate prevents birth defects are not well understood. We explore the use of zebrafish as a model system to investigate the role of folate metabolism during development...
Phoenix is required for mechanosensory hair cell regeneration in the zebrafish lateral lineMartine Behra
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
PLoS Genet 5:e1000455. 2009..Whereas its role during early development of the lateral line remains to be addressed, in later larval stages phoenix defines a new class of proteins implicated in hair cell regeneration...
The Zebrafish Insertion Collection (ZInC): a web based, searchable collection of zebrafish mutations generated by DNA insertionGaurav K Varshney
Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Nucleic Acids Res 41:D861-4. 2013..In the future, ZInC may include data from other insertional mutation projects as well. ZInC cross-references all integration data with the ZFIN (http://zfin.org/)...
The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15Zubair M Ahmed
Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland 20850, USA
J Neurosci 26:7022-34. 2006..Protocadherin-15 is therefore associated with the tip-link complex and may be an integral component of this structure and/or required for its formation...
The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structureJizhou Yan
National Human Genome Research Institute, Genome Technology Branch, NIH, Bldg 50, Rm 5537, 50 South Dr, Bethesda, MD 20892, USA
Mol Cell Biol 26:155-68. 2006..On the basis of these findings, we propose that FoxI1 is capable of remodeling chromatin higher-order structure and can stably create site-specific changes in chromatin to either stably create or remove DNase I hypersensitive sites...
Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCORDavid Ng
Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
Nat Genet 36:411-6. 2004....
