Peter D Burbelo

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Genome-wide association studies in Sjögren's syndrome: What do the genes tell us about disease pathogenesis?
    Peter D Burbelo
    Dental Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA Electronic address
    Autoimmun Rev 13:756-61. 2014
  2. pmc Altered antibody profiles against common infectious agents in chronic disease
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e81635. 2013
  3. pmc The serological evidence in humans supports a negligible risk of zoonotic infection from porcine circovirus type 2
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA Electronic address
    Biologicals 41:430-4. 2013
  4. pmc Lack of serum antibodies against Borrelia burgdorferi in children with autism
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    Clin Vaccine Immunol 20:1092-3. 2013
  5. pmc Extrapancreatic autoantibody profiles in type I diabetes
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, and National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 7:e45216. 2012
  6. pmc New technologies for studying the complexity of oral diseases
    P D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Dis 18:121-6. 2012
  7. pmc Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e22576. 2011
  8. pmc Rapid induction of autoantibodies during ARDS and septic shock
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Transl Med 8:97. 2010
  9. pmc Antibody-profiling technologies for studying humoral responses to infectious agents
    Peter D Burbelo
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    Expert Rev Vaccines 9:567-78. 2010
  10. pmc Antibody profiling of Borrelia burgdorferi infection in horses
    Peter D Burbelo
    National Institutes of Health, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 18:1562-7. 2011

Detail Information

Publications51

  1. ncbi request reprint Genome-wide association studies in Sjögren's syndrome: What do the genes tell us about disease pathogenesis?
    Peter D Burbelo
    Dental Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA Electronic address
    Autoimmun Rev 13:756-61. 2014
    ....
  2. pmc Altered antibody profiles against common infectious agents in chronic disease
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e81635. 2013
    ..The results suggest that antibody profiles against these and likely other common infectious agents may yield insight into the interplay between exposure to infectious agents, dysbiosis, adaptive immunity and disease activity. ..
  3. pmc The serological evidence in humans supports a negligible risk of zoonotic infection from porcine circovirus type 2
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA Electronic address
    Biologicals 41:430-4. 2013
    ..These results extend the extensively demonstrated use of LIPS as a robust approach for identifying humoral responses and provide evidence that PCV-2 is likely not infectious in humans. ..
  4. pmc Lack of serum antibodies against Borrelia burgdorferi in children with autism
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    Clin Vaccine Immunol 20:1092-3. 2013
    ..No seropositivity against Borrelia burgdorferi was detected in the children with and without autism. There was no evidence of an association between Lyme disease and autism. ..
  5. pmc Extrapancreatic autoantibody profiles in type I diabetes
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, and National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 7:e45216. 2012
    ..Taken together, these results suggest that autoantibody portraits derived from islet and organ-specific targets will likely be useful for enhancing the clinical management of T1D...
  6. pmc New technologies for studying the complexity of oral diseases
    P D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Oral Dis 18:121-6. 2012
    ..We propose that the information offered by these technologies will enhance our ability to diagnose, treat, and further understand the pathogenesis of multiple oral diseases...
  7. pmc Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 6:e22576. 2011
    ..Together these results document human humoral responses to HMOAstV-C and validate LIPS as a facile and effective approach for identifying humoral responses to novel infectious agents...
  8. pmc Rapid induction of autoantibodies during ARDS and septic shock
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Transl Med 8:97. 2010
    ....
  9. pmc Antibody-profiling technologies for studying humoral responses to infectious agents
    Peter D Burbelo
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 49, Room 1C20, 49 Convent Drive, Bethesda, MD 20892 4410, USA
    Expert Rev Vaccines 9:567-78. 2010
    ..We also describe LIPS in detail and discuss several clinically relevant uses of the technology. Together, these new technologies offer new tools for understanding humoral responses to known and emerging infectious agents...
  10. pmc Antibody profiling of Borrelia burgdorferi infection in horses
    Peter D Burbelo
    National Institutes of Health, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 18:1562-7. 2011
    ..These results suggest that LIPS tests employing multiple recombinant antigens offer a promising approach for the evaluation of antibody responses in Lyme disease...
  11. pmc Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 201:1919-22. 2010
    ..These results suggest that antibody responses to lytic and latent KS-associated herpesvirus antigens differ in these diseases...
  12. pmc Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, 49 Convent Drive, Building 49, Room 1C20, NIDCR, NIH, Bethesda, MD 20892 4410, USA
    Clin Vaccine Immunol 17:904-9. 2010
    ..These results suggest that screening by the LIPS test with VOVO and other B. burgdorferi antigens offers an efficient quantitative approach for evaluation of the antibody responses in patients with Lyme disease...
  13. pmc Rapid serological detection of autoantibodies associated with Sjögren's syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Transl Med 7:83. 2009
    ..Here we investigated whether a quick version of luciferase immunoprecipitation systems (QLIPS) could be used to produce a rapid, specific and quantitative test to detect autoantibodies associated with SjS...
  14. pmc LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Biosyst 7:1453-62. 2011
    ..These results suggest that LIPS arrays offer a highly discriminating platform for simultaneously profiling a wide spectrum of antibodies associated with many infectious agents...
  15. pmc Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Retrovirology 5:96. 2008
    ..Antibody profiles were correlated with viral load and examined in longitudinal samples...
  16. pmc Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Virol J 6:45. 2009
    ..Currently, there is a need for improved quantitative serological tests to document seropositivity with high sensitivity and specificity...
  17. pmc Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Autoimmunity 42:515-24. 2009
    ..These heterogeneous autoantibody responses detected by LIPS in SjS will likely be useful for diagnosis and for evaluating extraglandular manifestations...
  18. pmc Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892 44101, USA
    Clin Vaccine Immunol 16:621-7. 2009
    ..These results suggest that LIPS screening using an antigen mixture is a sensitive and high-throughput method for serological screening of HHV-8 infection in individuals with KS...
  19. pmc A four-antigen mixture for rapid assessment of Onchocerca volvulus infection
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Negl Trop Dis 3:e438. 2009
    ..We investigated whether luciferase immunoprecipitation systems (LIPS) may be used as a more rapid, specific, and standardized diagnostic assay for Onchocerca volvulus infection...
  20. pmc Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 33:754-6. 2010
    ....
  21. pmc Quantitative determinations of anti-Kaposi sarcoma-associated herpesvirus antibody levels in men who have sex with men
    Emile Gogineni
    Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    Diagn Microbiol Infect Dis 76:56-60. 2013
    ..These findings also suggest that antibodies against v-cyclin and ORF38 are useful for identifying patients with asymptomatic KSHV infection...
  22. pmc Soluble rhesus lymphocryptovirus gp350 protects against infection and reduces viral loads in animals that become infected with virus after challenge
    Junji Sashihara
    Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 7:e1002308. 2011
    ..Our results suggest that additional trials with soluble EBV gp350 alone, or in combination with other EBV proteins, should be considered to reduce EBV infection or virus-associated malignancies in humans...
  23. pmc Serological diagnosis of human herpes simplex virus type 1 and 2 infections by luciferase immunoprecipitation system assay
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Clin Vaccine Immunol 16:366-71. 2009
    ....
  24. pmc A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection
    Roshan Ramanathan
    Clinical Parasitology Unit and Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 198:444-51. 2008
    ..We investigated whether luciferase immunoprecipitation systems (LIPS) can be the basis for a more rapid, specific, and standardized assay for the diagnosis of Strongyloides stercoralis infection...
  25. pmc Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 202:894-8. 2010
    ..These results suggest that profiling anti-HCV antibody is useful for monitoring HCV therapy, especially in discriminating between those who experience relapse and those who have SVRs at 48 weeks...
  26. pmc Serology-enabled discovery of genetically diverse hepaciviruses in a new host
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 86:6171-8. 2012
    ..Together, these findings suggest a promising new nonprimate animal model and provide a database that will aid creation of functional NPHV cDNA clones and other novel tools for hepacivirus studies...
  27. pmc Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Expert Rev Proteomics 8:309-16. 2011
    ....
  28. pmc Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bethesda, MD 20892 4410, United States
    Neuromuscul Disord 21:204-13. 2011
    ....
  29. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010
    ..This study was registered at http://clinicaltrials.gov as NCT00001355...
  30. pmc Two major autoantibody clusters in systemic lupus erythematosus
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, Maryland, United States of America
    PLoS ONE 7:e32001. 2012
    ....
  31. pmc The clinical relevance of persistent recombinant immunoblot assay-indeterminate reactions: insights into the natural history of hepatitis C virus infection and implications for donor counseling
    Addisalem T Makuria
    Infectious Disease Section, Department of Transfusion Medicine, National Institute for Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Transfusion 52:1940-8. 2012
    ..We addressed the clinical relevance of these reactions in the context of the natural history of HCV infection in a prospectively followed cohort of anti-HCV-positive blood donors...
  32. doi request reprint Adult-onset immunodeficiency in Thailand and Taiwan
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    N Engl J Med 367:725-34. 2012
    ..Autoantibodies against interferon-γ are associated with severe disseminated opportunistic infection, but their importance and prevalence are unknown...
  33. pmc High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance
    Kathryn H Ching
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, 49 Convent Drive, Bldg 49, 1C20, Bethesda, Maryland, 20892 4410, United States
    J Neuroimmunol 222:87-9. 2010
    ..These results suggest the possibility that CNS autoimmunity may be responsible for the psychomotor impairment in this MDD patient...
  34. pmc Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs
    Yo Hoshino
    Medical Virology Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 200:1088-95. 2009
    ..A herpes simplex virus (HSV)-2 candidate vaccine consisting of glycoprotein D (gD2) in alum and monophosphoryl lipid A (MPL) reduced genital herpes disease in HSV-1-seronegative women but not in men or HSV-1-seropositive women...
  35. pmc No serological evidence for a role of HHV-6 infection in chronic fatigue syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, MD
    Am J Transl Res 4:443-51. 2012
    ..These findings highlight the utility of LIPS for exploring the seroepidemiology of HHV-6A and HHV-6B infection, but suggest that these viruses are unlikely to play a role in the pathogenesis of CFS...
  36. pmc High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 366:1-7. 2008
    ..This study validates LIPS as a robust method to interrogate autoantibodies for the diagnosis of SPS and potentially other neurological diseases...
  37. ncbi request reprint HIV antibody characterization as a method to quantify reservoir size during curative interventions
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research
    J Infect Dis 209:1613-7. 2014
    ..Comprehensive HIV antibody profiles may prove useful for monitoring curative interventions. ..
  38. pmc Microfluidic LIPS for serum antibody detection: demonstration of a rapid test for HSV-2 infection
    Adnan Zubair
    Microfabrication and Microfluidics Unit, Biomedical Engineering and Physical Science Shared Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bldg 13, Rm 3N18, 13 South Drive, Bethesda, MD 20892 5766, USA
    Biomed Microdevices 13:1053-62. 2011
    ..Based on these findings, the LIPS microfluidic format should readily lend itself to automation and the transfer to portable instrumentation...
  39. pmc A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2
    Peter D Burbelo
    Sensory Biology Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 31:1824-6. 2008
    ..The present experiments were initiated to develop a new assay that does not require the use of radioisotopes or autoantigens prepared in bacteria or by in vitro transcription/translation...
  40. pmc Human antibody titers to Epstein-Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay
    Junji Sashihara
    Medical Virology Section, Laboratory of Clinical Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Virology 391:249-56. 2009
    ..Furthermore, we show that antibody titers to EBV gp350 correlate more strongly with neutralization than antibody titers to gp42. These assays should be useful in accessing antibody responses to candidate EBV vaccines...
  41. pmc Commercial multiplex technologies for the microbiological diagnosis of sepsis
    Evan E Lebovitz
    Department of Perioperative Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Mol Diagn Ther 17:221-31. 2013
    ..We discuss the current clinical impact, limitations, and likely futures advances these multiplex technologies may have in guiding the management of patients with sepsis. ..
  42. pmc Comprehensive analysis of unique cases with extraordinary control over HIV replication
    Daniel Mendoza
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
    Blood 119:4645-55. 2012
    ..Additional insight into the full spectrum of immune-mediated suppression over HIV replication may enhance our understanding of the associated mechanisms, which should inform the design of efficacious HIV vaccines and immunotherapies...
  43. pmc Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, 4 Center Drive, Bethesda, Maryland 20892, USA
    J Clin Microbiol 46:2298-304. 2008
    ..These results suggest that LIPS (and the even more rapid test QLIPS) represents a major advance in the ability to diagnose L. loa infection and may have future applications for point-of-care diagnostics...
  44. pmc Emerging tactical strategies for fighting the war on cancer based on the genetic landscape
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, MD 20892, USA
    Am J Transl Res 3:251-8. 2011
    ..Capitalizing on these and other advances represent a new turning point in the war on cancer...
  45. pmc Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States
    Jeffrey I Cohen
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA
    Blood 117:5835-49. 2011
    ..These studies are registered at http://www.clinicaltrials.gov as NCT00032513 for CAEBV, NCT00062868 and NCT00058812 for EBV-specific T-cell studies, and NCT00578539 for the hematopoietic stem cell transplantation protocol...
  46. pmc Synthetic biology for translational research
    Peter D Burbelo
    Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health Bethesda, MD 20892, USA
    Am J Transl Res 2:381-9. 2010
    ..Together these and other novel translational applications of artificial gene synthesis and synthetic biology have the opportunity to make major advances for improving human health...
  47. ncbi request reprint A seroprevalence study of primate workers for asymptomatic rhesus cytomegalovirus infection
    J Jason Bowman
    Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States
    J Clin Virol 60:411-3. 2014
    ..While, rhesus CMV (RhCMV) infects human cells in culture, it is unknown whether the virus can infect humans...
  48. pmc Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine
    John H Beigel
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 200:501-9. 2009
    ..We sought to generate high-titer H5N1 antibodies in healthy volunteers for the purpose of developing hyperimmune intravenous immunoglobulin...
  49. pmc Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction
    Bruce J Baum
    Molecular Physiology and Therapeutics Branch, and Neurobiology and Pain Therapeutics Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:19403-7. 2012
    ..AdhAQP1 vector delivery to a single parotid gland was safe and transfer of the hAQP1 cDNA increased parotid flow and relieved symptoms in a subset of subjects...
  50. doi request reprint Graves' disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4(+) T-cell recovery
    Virginia Sheikh
    aNational Institute of Allergy and Infectious Diseases NIAID bBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda cScience Applications International Corporation Frederick, Frederick National Laboratory, Frederick dClinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
    AIDS 28:31-9. 2014
    ..Although IRD usually occurs in the first months of ART during memory CD4 T-cell recovery, Graves' disease occurs as a distinctive late-onset IRD and its pathogenesis is unclear...