Research Topics
Species | Ronald R BuggageSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet's diseaseRonald R Buggage
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892 1857, USA
Ocul Immunol Inflamm 15:63-70. 2007..To investigate the safety and efficacy of daclizumab (Zenapax, humanized anti-Tac, HAT) in controlling the ocular manifestations of Behçet's disease...
Ocular manifestations of human T-cell lymphotropic virus type 1 infectionRonald R Buggage
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892 1857, USA
Curr Opin Ophthalmol 14:420-5. 2003..This report reviews the recent developments and ocular findings reported in patients with HTLV-1-related diseases...
Effect of sex hormones on experimental autoimmune uveoretinitis (EAU)Ronald R Buggage
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
Immunol Invest 32:259-73. 2003..We evaluated the effect of estrogen, progesterone, and testosterone in autoimmune uveoretinitis (EAU), a rodent model of human ocular autoimmune disease...
Initial evaluation of subcutaneous daclizumab treatments for noninfectious uveitis: a multicenter noncomparative interventional case seriesRobert B Nussenblatt
Laboratory of Immunology, National Eye Institute, Bethesda, Maryland 20892, USA
Ophthalmology 112:764-70. 2005....
Intravitreal methotrexate resistance in a patient with primary intraocular lymphomaH Nida Sen
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
Ocul Immunol Inflamm 16:29-33. 2008..To describe the clinical course of a patient with multiple recurrences of primary intraocular lymphoma (PIOL)...
Detection of the bcl-2 t(14;18) translocation and proto-oncogene expression in primary intraocular lymphomaDana J Wallace
Laboratory of Immunology, Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20895 1857, USA, and Department of Ophthalmology, Tokyo Medical and Dental University, Japan
Invest Ophthalmol Vis Sci 47:2750-6. 2006..This study examined the expression of the bcl-2 t(14;18) translocation, the bcl-10 gene, and high expression of bcl-6 mRNA in PIOL cells...
Primary testicular and intraocular lymphomas: two case reports and a review of the literatureDana J Wallace
National Eye Institute/NIH, Bldg. 10, 10 Center Drive, Bethesda, MD 20892, USA
Surv Ophthalmol 51:41-50. 2006..Clinicians should be suspicious for intraocular lymphoma in patients with a history of testicular lymphoma who present with vitritis or retinal lesions...
Progressive outer retinal necrosis in the era of highly active antiretroviral therapy: successful management with intravitreal injections and monitoring with quantitative PCRPhilip D Yin
National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
J Clin Virol 38:254-9. 2007..Progressive outer retinal necrosis (PORN) is an ocular disease in individuals with AIDS and is associated with substantial morbidity. The optimal management of PORN and its clinical course in the HAART era is unclear...
Humanized anti-interleukin-2 (IL-2) receptor alpha therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administrationRobert B Nussenblatt
The National Eye Institute, Laboratory of Immunology, NIH, Building 10, 10 Center Drive, Bethesda, MD, USA
J Autoimmun 21:283-93. 2003..These studies suggest that anti-IL-2 receptor blockade could be useful in the treatment of Th1-mediated autoimmune conditions...
Hypergammaglobulinemia and corneal opacities in patients with human T-cell lymphotrophic virus type-1Marena Patronas
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Am J Ophthalmol 142:1088-9. 2006..99). CONCLUSION: Although the mechanism remains unclear, hypergammaglobulinemia is associated with the development of the corneal opacities in patients of African descent with ATL...
Expression of chemokine receptors, CXCR4 and CXCR5, and chemokines, BLC and SDF-1, in the eyes of patients with primary intraocular lymphomaChi Chao Chan
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bldg 10, Rm 10N103, 90 Center Drive, Bethesda, MD 20892 1857, USA
Ophthalmology 110:421-6. 2003..We investigated the expression of these chemokine/chemokine receptors in eyes with primary intraocular B-cell lymphoma (PIOL)...
Bilateral uveitis in a patient with autoimmune lymphoproliferative syndromeWee-Kiak Lim
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1857, USA
Am J Ophthalmol 139:562-3. 2005..The pathogenesis of uveitis in ALPS may differ from that of the systemic disease overall. Long-term follow-up is required for patients with uveitis associated with ALPS...
Serpiginous choroiditisWee-Kiak Lim
National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA; and Singapore National Eye Centre, Singapore
Surv Ophthalmol 50:231-44. 2005..Larger clinical studies and interventional trials are required to further our understanding of the pathogenesis, etiology, and for the evaluation of treatment strategies...
Occult primary carcinoma metastatic to the irisH Nida Sen
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
Acta Ophthalmol Scand 82:746-7. 2004
Waldenström's macroglobulinemia-associated retinopathyH Nida Sen
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Building 10, Room 10N112, 9000 Rockville Pike, Bethesda, MD 20892-1857, USA
Ophthalmology 111:535-9. 2004..CONCLUSION: The paraneoplastic retinopathy associated with Waldenström's macroglobulinemia in this patient is presumed to result from antibodies of the IgM subtype reacting to proteins in the retinal photoreceptors...
Gamma interferon assay as an alternative to PPD skin testing in selected patients with granulomatous intraocular inflammatory diseaseShree K Kurup
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA
Can J Ophthalmol 41:737-40. 2006....
Conjunctival papillomas caused by human papillomavirus type 33Ronald R Buggage
National Eye Institute, National Institutes of Health, Bethesda, MD 20892-1857, USA
Arch Ophthalmol 120:202-4. 2002
Malignant cerebellar swelling in Behçet disease. Case illustrationRussell R Lonser
Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1414, USA
J Neurosurg 103:292. 2005
Expression of glucocorticoid induced TNF receptor family related protein (GITR) on peripheral T cells from normal human donors and patients with non-infectious uveitisZhuqing Li
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Building 10, 10B22, 10 Center Drive, Bethesda, MD 20892 1857, USA
J Autoimmun 21:83-92. 2003..Therefore, GITR is an activation marker for the CD4+ T cells and preferentially co-expressed with CD25 on the CD4+ T cells in human peripheral blood. Its expression correlates with the clinical course of non-infectious uveitis...
Intraocular lymphomaChi Chao Chan
Laboratory of Immunology National Eye Institute, National Institutes of Health, Building 10 Room 10N103, 10 Center Drive, Bethesda, MD 20892 1857, USA
Curr Opin Ophthalmol 13:411-8. 2002..Compared with PIOL, metastatic systemic lymphomas have a much lower prevalence, better prognosis, and are less likely to create a diagnostic dilemma...
Mycophenolate mofetil for the treatment of scleritisH Nida Sen
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1857, USA
Ophthalmology 110:1750-5. 2003....
Human T-cell lymphotropic virus type-1 associated t-cell leukemia/lymphoma masquerading as necrotizing retinal vasculitisGrace A Levy-Clarke
Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ophthalmology 109:1717-22. 2002..This case further demonstrates the usefulness of microdissection and PCR for the diagnosis of ocular disease, including HTLV-1 infection...
Vitreous cytokine levelsLesley A Wolf
Ophthalmology 110:1671-2. 2003
