Susan K Buchanan

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A structural comparison of human serum transferrin and human lactoferrin
    Jeremy Wally
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA
    Biometals 20:249-62. 2007
  2. pmc Bacterial metal detectors
    Susan K Buchanan
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Mol Microbiol 58:1205-9. 2005
  3. pmc Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import
    Susan K Buchanan
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    EMBO J 26:2594-604. 2007
  4. pmc Structural insights into Ail-mediated adhesion in Yersinia pestis
    Satoshi Yamashita
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
    Structure 19:1672-82. 2011
  5. ncbi request reprint Structure of the OmpA-like domain of RmpM from Neisseria meningitidis
    Sylvestre Grizot
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Mol Microbiol 51:1027-37. 2004
  6. pmc Structural basis for iron piracy by pathogenic Neisseria
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 483:53-8. 2012
  7. ncbi request reprint Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA
    Wyatt W Yue
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 332:353-68. 2003
  8. pmc Using a bacteriocin structure to engineer a phage lysin that targets Yersinia pestis
    Petra Lukacik
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem Soc Trans 40:1503-6. 2012
  9. pmc TonB-dependent transporters: regulation, structure, and function
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Microbiol 64:43-60. 2010
  10. pmc Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Structure 20:1233-43. 2012

Collaborators

Detail Information

Publications23

  1. pmc A structural comparison of human serum transferrin and human lactoferrin
    Jeremy Wally
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA
    Biometals 20:249-62. 2007
    ..Comparison of the recently solved crystal structure of iron-free human serum transferrin to that of human lactoferrin provides insight into these differences...
  2. pmc Bacterial metal detectors
    Susan K Buchanan
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Mol Microbiol 58:1205-9. 2005
    ..The new structure extends our knowledge of transporter architecture and suggests how signalling may occur across the outer membrane...
  3. pmc Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import
    Susan K Buchanan
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    EMBO J 26:2594-604. 2007
    ..Functional data using full-length colicin Ia show that colicin I receptor is necessary for cell surface binding, and suggest that the receptor participates in translocation of colicin Ia across the outer membrane...
  4. pmc Structural insights into Ail-mediated adhesion in Yersinia pestis
    Satoshi Yamashita
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
    Structure 19:1672-82. 2011
    ..We also evaluated the contribution of laminin to delivery of Yops to HEp-2 cells. This work constitutes a structural description of how a bacterial outer membrane protein uses a multivalent approach to bind host cells...
  5. ncbi request reprint Structure of the OmpA-like domain of RmpM from Neisseria meningitidis
    Sylvestre Grizot
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Mol Microbiol 51:1027-37. 2004
    ....
  6. pmc Structural basis for iron piracy by pathogenic Neisseria
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 483:53-8. 2012
    ..Our studies provide a rational basis for the specificity of TbpA for human transferrin, show how TbpA promotes iron release from transferrin, and elucidate how TbpB facilitates this process...
  7. ncbi request reprint Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA
    Wyatt W Yue
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 332:353-68. 2003
    ....
  8. pmc Using a bacteriocin structure to engineer a phage lysin that targets Yersinia pestis
    Petra Lukacik
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem Soc Trans 40:1503-6. 2012
    ..This work provides a template for engineering phage lysins against a wide variety of bacterial pathogens...
  9. pmc TonB-dependent transporters: regulation, structure, and function
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Microbiol 64:43-60. 2010
    ..However, the transport mechanism is still unclear. In this review, we summarize recent progress in understanding regulation, structure, and function in TBDTs and questions remaining to be answered...
  10. pmc Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Structure 20:1233-43. 2012
    ..We then use this set of sequences along with our structural data to find and map the evolutionarily constrained residues within the β domain...
  11. pmc Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter
    Travis J Barnard
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 415:128-42. 2012
    ..Together, these findings provide insight into factors important for asparagine cyclization, a mechanism broadly used for protein cleavage...
  12. pmc Signaling mechanisms for activation of extracytoplasmic function (ECF) sigma factors
    Benjamin E Brooks
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1778:1930-45. 2008
    ..coli. Homologues from other Gram-negative bacteria suggest that these two signaling mechanisms and variations on these mechanisms may be the general schemes by which ECF sigma factors are regulated in Gram-negative bacteria...
  13. pmc Structural engineering of a phage lysin that targets gram-negative pathogens
    Petra Lukacik
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:9857-62. 2012
    ....
  14. pmc Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Bacteriol 194:499-508. 2012
    ....
  15. pmc The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding
    Jeremy Wally
    NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 281:24934-44. 2006
    ..In addition, we evaluate potential interactions between apo-hTF and the human transferrin receptor...
  16. pmc The transferrin-iron import system from pathogenic Neisseria species
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Microbiol 86:246-57. 2012
    ....
  17. pmc Autotransporter structure reveals intra-barrel cleavage followed by conformational changes
    Travis J Barnard
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Struct Mol Biol 14:1214-20. 2007
    ....
  18. ncbi request reprint Crystallization of integral membrane proteins
    Travis J Barnard
    National Institutes of Health, Bethesda, Maryland, USA
    Curr Protoc Protein Sci . 2007
    ..These protocols were established for outer membrane proteins, but can be used for inner membrane proteins as well. Advice on alternative protocols, detergent selection, and optimization of crystallization conditions is provided...
  19. pmc The structural biology of β-barrel membrane proteins: a summary of recent reports
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Struct Biol 21:523-31. 2011
    ..However, they demonstrate many of the advancements made within the field of transmembrane protein structure in the past few years...
  20. pmc The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
    J Mol Biol 407:248-60. 2011
    ..This may facilitate integration of newly synthesized OMPs into the outer membrane...
  21. pmc Role of the Yersinia pestis Ail protein in preventing a protective polymorphonuclear leukocyte response during bubonic plague
    B Joseph Hinnebusch
    Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
    Infect Immun 79:4984-9. 2011
    ..pestis F1 antigen. The Y. pestis Ail protein is an important bubonic plague virulence factor that inhibits the innate immune response, in particular the recruitment of a protective PMN response to the infected lymph node...
  22. ncbi request reprint Recognition of iron-free siderophores by TonB-dependent iron transporters
    Isabelle J Schalk
    Département des Récepteurs et Protéines Membranaires, UPR 9050, CNRS, ESBS, Bld Sébastien Brant, F 67 400 Illkirch, Strasbourg, France
    Mol Microbiol 54:14-22. 2004
    ....
  23. pmc Colicin biology
    Eric Cascales
    Laboratoire d Ingenierie des Systemes Macromoleculaires, Institut de Biologie Structurale et Microbiologie, Centre National de la Recherche Scientifique, UPR 9027, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    Microbiol Mol Biol Rev 71:158-229. 2007
    ..The mechanisms of inhibition by specific and cognate immunity proteins are presented. Finally, the use of colicins as laboratory or biotechnological tools and their mode of evolution are discussed...