Sarah K Browne

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Anti-CD20 (rituximab) therapy for anti-IFN-γ autoantibody-associated nontuberculous mycobacterial infection
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 119:3933-9. 2012
  2. doi request reprint Anticytokine autoantibody-associated immunodeficiency
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 email
    Annu Rev Immunol 32:635-57. 2014
  3. doi request reprint Adult-onset immunodeficiency in Thailand and Taiwan
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    N Engl J Med 367:725-34. 2012
  4. pmc Immunodeficiency secondary to anticytokine autoantibodies
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Curr Opin Allergy Clin Immunol 10:534-41. 2010
  5. pmc Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
    Elizabeth P Sampaio
    Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Allergy Clin Immunol 131:1624-34. 2013
  6. pmc Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome
    Gulbu Uzel
    Laboratory of Clinical Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1684, USA
    J Allergy Clin Immunol 131:1611-23. 2013
  7. pmc Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis
    Lindsey B Rosen
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 190:3959-66. 2013
  8. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010
  9. doi request reprint Determination of human anticytokine autoantibody profiles using a particle-based approach
    Li Ding
    Laboratory of Clinical Infectious Diseases, National Institutes of Allergy and Infectious Diseases, Bethesda, MD 20892 1684, USA
    J Clin Immunol 32:238-45. 2012
  10. doi request reprint Anticytokine autoantibodies in infectious diseases: pathogenesis and mechanisms
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Lancet Infect Dis 10:875-85. 2010

Collaborators

Detail Information

Publications13

  1. pmc Anti-CD20 (rituximab) therapy for anti-IFN-γ autoantibody-associated nontuberculous mycobacterial infection
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 119:3933-9. 2012
    ....
  2. doi request reprint Anticytokine autoantibody-associated immunodeficiency
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 email
    Annu Rev Immunol 32:635-57. 2014
    ..This review focuses on the current understanding, both clinical and mechanistic, of anticytokine autoantibody-associated immunodeficiency. ..
  3. doi request reprint Adult-onset immunodeficiency in Thailand and Taiwan
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    N Engl J Med 367:725-34. 2012
    ..Autoantibodies against interferon-γ are associated with severe disseminated opportunistic infection, but their importance and prevalence are unknown...
  4. pmc Immunodeficiency secondary to anticytokine autoantibodies
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Curr Opin Allergy Clin Immunol 10:534-41. 2010
    ..We will review the clinical and laboratory features of syndromes in which immunodeficiency is caused by or associated with neutralizing anticytokine autoantibodies...
  5. pmc Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
    Elizabeth P Sampaio
    Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Allergy Clin Immunol 131:1624-34. 2013
    ..Dominant gain-of-function mutations in signal transducer and activator of transcription 1 (STAT1) have been associated with chronic mucocutaneous candidiasis...
  6. pmc Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome
    Gulbu Uzel
    Laboratory of Clinical Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1684, USA
    J Allergy Clin Immunol 131:1611-23. 2013
    ..The hypermorphic mutations are also associated with arterial aneurysms, autoimmunity, and squamous cell cancers...
  7. pmc Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis
    Lindsey B Rosen
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 190:3959-66. 2013
    ..This effect was limited to their IgG fraction. Anti-GM-CSF autoantibodies are associated with some cases of cryptococcal meningitis in otherwise immunocompetent patients. These cases need not have associated PAP...
  8. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010
    ..This study was registered at http://clinicaltrials.gov as NCT00001355...
  9. doi request reprint Determination of human anticytokine autoantibody profiles using a particle-based approach
    Li Ding
    Laboratory of Clinical Infectious Diseases, National Institutes of Allergy and Infectious Diseases, Bethesda, MD 20892 1684, USA
    J Clin Immunol 32:238-45. 2012
    ..We sought to develop a standardizable assay that is rapid, sensitive, and specific and able to simultaneously detect multiple anticytokine autoantibodies in small volumes (<10 μl)...
  10. doi request reprint Anticytokine autoantibodies in infectious diseases: pathogenesis and mechanisms
    Sarah K Browne
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Lancet Infect Dis 10:875-85. 2010
    ..Their protean roles in causing, treating, preventing, and responding to disease, as well as simply maintaining normal homoeostasis, offer fascinating insights into the biology of immunity, inflammation, and infection...
  11. pmc Altered antibody profiles against common infectious agents in chronic disease
    Peter D Burbelo
    Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e81635. 2013
    ..The results suggest that antibody profiles against these and likely other common infectious agents may yield insight into the interplay between exposure to infectious agents, dysbiosis, adaptive immunity and disease activity. ..
  12. doi request reprint Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial
    Arun Rajan
    Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Lancet Oncol 15:191-200. 2014
    ..We investigated the efficacy of cixutumumab, a fully human IgG1 monoclonal antibody targeting the insulin-like growth factor 1 receptor in thymic epithelial tumours after failure of previous chemotherapy...
  13. doi request reprint A3.31 Rheumatoid arthritis, sjogren's syndrome and systemic lupus erythematosus patients have a distinct spectrum of serum anticytokine autoantibodies
    Sarthak Gupta
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda
    Ann Rheum Dis 73:A54-5. 2014
    ..We comprehensively evaluated anticytokine autoantibodies in Rheumatoid Arthritis (RA), Sjogren's Syndrome (SS) and Systemic Lupus Erythematosus (SLE)...