Rebecca J Brown

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data
    Rebecca J Brown
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Pediatr Diabetes 9:14-22. 2008
  2. pmc Metreleptin improves blood glucose in patients with insulin receptor mutations
    Rebecca J Brown
    MD, MHSC, Building 10 CRC, Room 6 5942, 10 Center Drive, Bethesda, Maryland 20892
    J Clin Endocrinol Metab 98:E1749-56. 2013
  3. pmc Non-nutritive sweeteners and their role in the gastrointestinal tract
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 1645, USA
    J Clin Endocrinol Metab 97:2597-605. 2012
  4. pmc Effects of diet soda on gut hormones in youths with diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 35:959-64. 2012
  5. pmc Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 31:1403-4. 2008
  6. pmc Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 32:2184-6. 2009
  7. pmc Artificial sweeteners: a systematic review of metabolic effects in youth
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Pediatr Obes 5:305-12. 2010
  8. ncbi request reprint Bone mineral content in patients with congenital generalized lipodystrophy is unaffected by metreleptin replacement therapy
    John D Christensen
    Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases J D C, E C, P G, K I R, R J B, National Institute of Dental and Craniofacial Research M T C, R I G, Nuclear Medicine Department, Clinical Center J C R, National Institutes of Health, Bethesda, Maryland 20892 and Joslin Diabetes Center A O L, Brookline, Massachusetts 02215
    J Clin Endocrinol Metab 99:E1493-500. 2014
  9. pmc Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes Technol Ther 13:457-60. 2011
  10. pmc Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes
    Kristina I Rother
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 32:1250-5. 2009

Collaborators

Detail Information

Publications17

  1. pmc Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data
    Rebecca J Brown
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Pediatr Diabetes 9:14-22. 2008
  2. pmc Metreleptin improves blood glucose in patients with insulin receptor mutations
    Rebecca J Brown
    MD, MHSC, Building 10 CRC, Room 6 5942, 10 Center Drive, Bethesda, Maryland 20892
    J Clin Endocrinol Metab 98:E1749-56. 2013
    ..Hyperglycemia in RMS is very difficult to treat, and patients are at risk for early morbidity and mortality from complications of diabetes...
  3. pmc Non-nutritive sweeteners and their role in the gastrointestinal tract
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 1645, USA
    J Clin Endocrinol Metab 97:2597-605. 2012
    ..Because consumption of non-nutritive sweeteners is common in the United States, understanding the physiological effects of these substances is of interest and importance...
  4. pmc Effects of diet soda on gut hormones in youths with diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 35:959-64. 2012
    ..In this study, we examined the effect of diet soda on gut hormones in youths with diabetes...
  5. pmc Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 31:1403-4. 2008
    ..To determine the time course of changes in glucagon and insulin secretion in children with recently diagnosed type 1 diabetes...
  6. pmc Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion
    Rebecca J Brown
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Diabetes Care 32:2184-6. 2009
    ..The goal of this study was to determine the effect of artificial sweeteners on glucose, insulin, and glucagon-like peptide (GLP)-1 in humans...
  7. pmc Artificial sweeteners: a systematic review of metabolic effects in youth
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Pediatr Obes 5:305-12. 2010
    ....
  8. ncbi request reprint Bone mineral content in patients with congenital generalized lipodystrophy is unaffected by metreleptin replacement therapy
    John D Christensen
    Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases J D C, E C, P G, K I R, R J B, National Institute of Dental and Craniofacial Research M T C, R I G, Nuclear Medicine Department, Clinical Center J C R, National Institutes of Health, Bethesda, Maryland 20892 and Joslin Diabetes Center A O L, Brookline, Massachusetts 02215
    J Clin Endocrinol Metab 99:E1493-500. 2014
    ..PATIENTS with congenital generalized lipodystrophy (CGL) have low leptin due to deficient adipose mass and serve as models of leptin deficiency and replacement...
  9. pmc Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes
    Rebecca J Brown
    National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes Technol Ther 13:457-60. 2011
    ..In this pilot study, we determined the effect of optimized insulin therapy on weight gain and frequency of hypoglycemia in patients with long-standing type 1 diabetes mellitus...
  10. pmc Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes
    Kristina I Rother
    National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 32:1250-5. 2009
    ..To evaluate the safety and efficacy of ingested human recombinant interferon-alpha (hrIFN-alpha) for preservation of beta-cell function in young patients with recent-onset type 1 diabetes...
  11. doi request reprint Challenging recruitment of youth with type 2 diabetes into clinical trials
    Tammy T Nguyen
    Section on Pediatric Diabetes and Metabolism, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    J Adolesc Health 54:247-54. 2014
    ..We explored whether similar strategies might be applicable to pediatric patients with type 2 diabetes...
  12. pmc Syndromic insulin resistance: models for the therapeutic basis of the metabolic syndrome and other targets of insulin resistance
    Phillip Gorden
    Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocr Pract 18:763-71. 2012
    ..To investigate the link between insulin resistance and the metabolic syndrome how to develop treatment approaches...
  13. pmc The liver diseases of lipodystrophy: the long-term effect of leptin treatment
    Elika Safar Zadeh
    Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States
    J Hepatol 59:131-7. 2013
    ..Non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) are also features of this condition. We studied the spectrum of liver disease in lipodystrophy and the effects of leptin replacement...
  14. pmc Clinical trials in youth with type 2 diabetes
    Julie Anne L Gemmill
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Pediatr Diabetes 12:50-7. 2011
    ..We conclude that type 2 diabetes in youth is an important but difficult new field of clinical research, and we discuss the existing barriers to successful recruitment, conduct, and support of these clinical trials...
  15. pmc Minocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae
    Rebecca J Brown
    Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Rockville, Maryland, USA
    Arch Dermatol 145:63-6. 2009
    ..Long-term autoimmune sequelae of DHS have been reported, including hypothyroidism...
  16. pmc Resolution of type 2 diabetes following bariatric surgery: implications for adults and adolescents
    Radha Nandagopal
    Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Diabetes Technol Ther 12:671-7. 2010
    ..Finally, we discuss the available data on bariatric surgery in adolescent patients, including special considerations in this potentially vulnerable population...
  17. pmc Cushing syndrome in the McCune-Albright syndrome
    Rebecca J Brown
    Clinical Endocrinology Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 4320, USA
    J Clin Endocrinol Metab 95:1508-15. 2010
    ..Cushing syndrome (CS) is a rare but potentially fatal feature of McCune-Albright syndrome (MAS). Optimal management, prognostic features, and long-term follow-up of this disorder have not been described...