Louise Brinton

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint In vitro fertilization and risk of breast and gynecologic cancers: a retrospective cohort study within the Israeli Maccabi Healthcare Services
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Fertil Steril 99:1189-96. 2013
  2. pmc Unopposed estrogen and estrogen plus progestin menopausal hormone therapy and lung cancer risk in the NIH-AARP Diet and Health Study Cohort
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Cancer Causes Control 23:487-96. 2012
  3. pmc Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Breast Cancer Res 10:R38. 2008
  4. ncbi request reprint Ovarian cancer risk after the use of ovulation-stimulating drugs
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7068, Bethesda, MD 20852 7234, USA
    Obstet Gynecol 103:1194-203. 2004
  5. ncbi request reprint Breast cancer risk associated with ovulation-stimulating drugs
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Hum Reprod 19:2005-13. 2004
  6. ncbi request reprint Ovarian cancer risk associated with varying causes of infertility
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20852, USA
    Fertil Steril 82:405-14. 2004
  7. ncbi request reprint Risk of connective tissue disorders among breast implant patients
    Louise A Brinton
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:619-27. 2004
  8. pmc Recent trends in breast cancer among younger women in the United States
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Bethesda, MD 20852 7234, USA
    J Natl Cancer Inst 100:1643-8. 2008
  9. ncbi request reprint Ethnicity and variation in breast cancer incidence
    L A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 73:349-55. 1997
  10. ncbi request reprint Ovulation induction and cancer risk
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Rockville, MD 20852, USA
    Fertil Steril 83:261-74; quiz 525-6. 2005

Detail Information

Publications101 found, 100 shown here

  1. doi request reprint In vitro fertilization and risk of breast and gynecologic cancers: a retrospective cohort study within the Israeli Maccabi Healthcare Services
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Fertil Steril 99:1189-96. 2013
    ..To assess long-term cancer risks associated with in vitro fertilization (IVF)...
  2. pmc Unopposed estrogen and estrogen plus progestin menopausal hormone therapy and lung cancer risk in the NIH-AARP Diet and Health Study Cohort
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Cancer Causes Control 23:487-96. 2012
    ..Previous studies have reported that lung cancer risk may be decreased, increased, or unaffected by prior use of menopausal hormone therapy (MHT)...
  3. pmc Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Breast Cancer Res 10:R38. 2008
    ..Epidemiologic evidence for a protective role of NSAIDs in breast cancer, however, is equivocal...
  4. ncbi request reprint Ovarian cancer risk after the use of ovulation-stimulating drugs
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7068, Bethesda, MD 20852 7234, USA
    Obstet Gynecol 103:1194-203. 2004
    ..To assess the long-term effects of ovulation-stimulating drugs on the risk of ovarian cancer...
  5. ncbi request reprint Breast cancer risk associated with ovulation-stimulating drugs
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Hum Reprod 19:2005-13. 2004
    ..Despite the recognized role of hormones in the aetiology of breast cancer, there has been little evaluation of hormonal preparations used to treat infertility...
  6. ncbi request reprint Ovarian cancer risk associated with varying causes of infertility
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20852, USA
    Fertil Steril 82:405-14. 2004
    ..To evaluate the risk of ovarian cancer as related to underlying causes of infertility...
  7. ncbi request reprint Risk of connective tissue disorders among breast implant patients
    Louise A Brinton
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:619-27. 2004
    ..Given the diagnostic complexities of these diseases, excess risks, if they exist, may be beyond detection even in a study of this size...
  8. pmc Recent trends in breast cancer among younger women in the United States
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Bethesda, MD 20852 7234, USA
    J Natl Cancer Inst 100:1643-8. 2008
    ..Continued surveillance of trends is needed, particularly for molecular subtypes that preferentially occur among young women...
  9. ncbi request reprint Ethnicity and variation in breast cancer incidence
    L A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 73:349-55. 1997
    ..Many of the analyses among younger women (20-39 years) were limited by available numbers, but it appeared that very little disease occurrence in young black women was associated with the factors studied...
  10. ncbi request reprint Ovulation induction and cancer risk
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Rockville, MD 20852, USA
    Fertil Steril 83:261-74; quiz 525-6. 2005
    ..To review and critique the literature regarding ovulation induction and cancer risk...
  11. pmc Do breast implants after a mastectomy affect subsequent prognosis and survival?
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Breast Cancer Res 7:61-3. 2005
    ..Additional well-designed investigations are needed to clarify survival patterns among women receiving reconstructive implants...
  12. pmc Relationships of uterine and ovarian tumors to pre-existing chronic conditions
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Gynecol Oncol 107:487-94. 2007
    ..Several chronic diseases have been hypothesized to affect the risk of subsequent gynecologic malignancies, possibly through shared hormonal mechanisms...
  13. ncbi request reprint Hormones and endometrial cancer--new data from the Million Women Study
    Louise A Brinton
    National Cancer Institute, Bethesda, MD 20892, USA
    Lancet 365:1517-8. 2005
  14. pmc Cancer risk among infertile women with androgen excess or menstrual disorders (including polycystic ovary syndrome)
    Louise A Brinton
    National Cancer Institute, Rockville, Maryland, USA
    Fertil Steril 94:1787-92. 2010
    ..To define relationships of androgen excesses to cancer risk...
  15. ncbi request reprint Relationship of benign gynecologic diseases to subsequent risk of ovarian and uterine tumors
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7068, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 14:2929-35. 2005
    ..Although endometriosis and uterine leiomyomas are common conditions, the extent to which either is associated with certain types of malignancies remains uncertain...
  16. ncbi request reprint Mortality rates among augmentation mammoplasty patients: an update
    Louise A Brinton
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Epidemiology 17:162-9. 2006
    ..A large follow-up study of cosmetic breast implant patients previously suggested an overall decrease in mortality but increased risks of brain and respiratory cancers and of suicides...
  17. ncbi request reprint Childhood tumor risk after treatment with ovulation-stimulating drugs
    Louise A Brinton
    Division of Cancer Epidemiology, National Cancer Institute, Bethesda, Maryland, USA
    Fertil Steril 81:1083-91. 2004
    ..To assess childhood cancer risk among children conceived following the use of ovulation-stimulating drugs...
  18. pmc Prospective evaluation of risk factors for male breast cancer
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7234, USA
    J Natl Cancer Inst 100:1477-81. 2008
    ..Differences in risk factors may reflect unique mechanisms associated with androgens and their ratio to bioavailable estrogens...
  19. ncbi request reprint Breast cancer risk in relation to amount of tissue removed during breast reduction operations in Sweden
    L A Brinton
    National Cancer Institute, 6120 Executive Plaza South, Rm 7068, Bethesda, MD 20892 7234, USA
    Cancer 91:478-83. 2001
    ..The current investigation attempted to assess whether the reduction in breast cancer risk was related directly to the amount of breast tissue removed...
  20. ncbi request reprint Long-term effects of ovulation-stimulating drugs on cancer risk
    Louise Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, 6120 Executive Blvd, Suite 550, Room 5018, Rockville, MD 20852 7234, USA
    Reprod Biomed Online 15:38-44. 2007
    ..This will also be important to fully resolve effects of exposures such as gonadotrophins, used more recently in conjunction with IVF...
  21. ncbi request reprint The relationship of silicone breast implants and cancer at other sites
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, Rockville, MD 20852 7234, USA
    Plast Reconstr Surg 120:94S-102S. 2007
    ....
  22. pmc Etiologic factors for male breast cancer in the U.S. Veterans Affairs medical care system database
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 5018, Rockville, MD 20852, USA
    Breast Cancer Res Treat 119:185-92. 2010
    ..21-8.03), obesity (1.91, 1.50-2.44), and orchitis/epididymitis (1.80, 1.08-3.01). These results support previous speculations that male breast cancer is influenced not only by tissue at risk, but also by hormonal and inflammatory factors...
  23. pmc Reproductive and hormonal factors and lung cancer risk in the NIH-AARP Diet and Health Study cohort
    Louise A Brinton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 20:900-11. 2011
    ..Inconsistent findings about hormonal factors on risk may reflect incomplete control for confounding, misclassification of exposures, or insufficient attention to variation by histology...
  24. ncbi request reprint Characteristics of a population of women with breast implants compared with women seeking other types of plastic surgery
    L A Brinton
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892 7234, USA
    Plast Reconstr Surg 105:919-27; discussion 928-9. 2000
    ....
  25. doi request reprint Breast cancer risk among patients with Klinefelter syndrome
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Acta Paediatr 100:814-8. 2011
    ..To evaluate male breast cancer (MBC) risk among patients with Klinefelter syndrome (KS) and relate this to possible biological explanations...
  26. pmc Menopausal hormone therapy and breast cancer risk in the NIH-AARP Diet and Health Study Cohort
    Louise A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA
    Cancer Epidemiol Biomarkers Prev 17:3150-60. 2008
    ..Results from the Women's Health Initiative trial raise new questions regarding the effects of estrogen therapy (ET) and estrogen plus progestin therapy (EPT) on breast cancer risk...
  27. pmc Reproductive risk factors for endometrial cancer among Polish women
    L A Brinton
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
    Br J Cancer 96:1450-6. 2007
    ..Alternative explanations for reproductive effects should be sought, including alterations in endogenous hormones...
  28. ncbi request reprint Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Room 7076, MSC 7234, Rockville, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 16:2269-75. 2007
    ..These differential associations are consistent with markedly different levels of GATA3 protein by ER status. Additional epidemiologic studies are needed to clarify these intriguing relationships...
  29. pmc Alcohol and risk of breast cancer by histologic type and hormone receptor status in postmenopausal women: the NIH-AARP Diet and Health Study
    Jasmine Q Lew
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD 20852, USA
    Am J Epidemiol 170:308-17. 2009
    ..13 (95% CI: 0.73, 1.77) for >20 g versus 0 g/day, and 1.21 (95% CI: 0.79, 1.84) for >20 g versus 0 g/day, respectively. Moderate consumption of alcohol was associated with breast cancer, specifically hormone receptor-positive tumors...
  30. ncbi request reprint Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer
    Yawei Zhang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:353-8. 2006
    ..6; 95% CI, 1.1-2.4; P = 0.02). In conclusion, our results do not support that the polymorphisms evaluated in six BER pathway genes play a major role in breast carcinogenesis, particularly in Caucasian populations...
  31. pmc A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Nat Genet 41:579-84. 2009
    ..1 (rs999737; P = 1.74 x 10(-7)) localizes to RAD51L1, a gene in the homologous recombination DNA repair pathway. We also confirmed associations with loci on chromosomes 2q35, 5p12, 5q11.2, 8q24, 10q26 and 16q12.1...
  32. pmc Body mass index and risk of ovarian cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Cancer 115:812-22. 2009
    ..However, to the authors' knowledge, data addressing whether the relation between BMI and ovarian cancer differs by MHT use are very sparse...
  33. ncbi request reprint Obesity as a potential risk factor for adenocarcinomas and squamous cell carcinomas of the uterine cervix
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Cancer 98:814-21. 2003
    ..The authors evaluated whether obesity, which can influence hormone levels, was associated with adenocarcinoma and squamous cell carcinoma...
  34. ncbi request reprint Uterine cancer after use of clomiphene citrate to induce ovulation
    Michelle D Althuis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
    Am J Epidemiol 161:607-15. 2005
    ..52, 95% CI: 1.5, 108.0). Clomiphene may increase uterine cancer risk, with higher doses leading to higher risk. Long-term follow-up of infertility cohorts is necessary to clarify the association between clomiphene use and uterine cancer...
  35. ncbi request reprint Lifetime weight history and endometrial cancer risk by type of menopausal hormone use in the NIH-AARP diet and health study
    Shih Chen Chang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Suite 320, Executive Plaza South, MSC7232, Bethesda, MD 20892 7232, USA
    Cancer Epidemiol Biomarkers Prev 16:723-30. 2007
    ..We conclude that both current adiposity and adult weight gain are associated with substantial increases in the risk of endometrial cancer, with relations particularly evident among never users of menopausal hormone therapy...
  36. pmc HSD17B1 genetic variants and hormone receptor-defined breast cancer
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 17:2766-72. 2008
    ..Associations between HSD17B1 genotypes and risk for ER- breast cancer were inconsistent across studies and should be studied further...
  37. pmc Prospective study of physical activity and risk of postmenopausal breast cancer
    Michael F Leitzmann
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Breast Cancer Res 10:R92. 2008
    ..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
  38. pmc Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers
    Xiaohong R Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Breast Cancer Res 14:R64. 2012
    ..Accordingly, we performed a masked microscopic assessment of TDLU involution in benign tissues associated with luminal A and CBP breast cancers diagnosed among women less than age 55 years...
  39. pmc Prediagnostic circulating follicle stimulating hormone concentrations and ovarian cancer risk
    Meghan A McSorley
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Int J Cancer 125:674-9. 2009
    ..These findings contradict the hypothesized role of FSH as a risk factor in ovarian carcinogenesis...
  40. ncbi request reprint Causes of infertility as predictors of subsequent cancer risk
    Louise A Brinton
    National Cancer Institute, Rockville, Maryland 20852 7234, USA
    Epidemiology 16:500-7. 2005
    ..Although studies have found elevated risks of certain cancers linked to infertility, the underlying reasons remain unclear...
  41. ncbi request reprint Serum selenium and the risk of cervical cancer among women in the United States
    Frances E Thompson
    National Cancer Institute, Division of Cancer Control and Population Sciences, Applied Research Program, Risk Factor Monitoring and Methods Branch, EPN 4016, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    Cancer Causes Control 13:517-26. 2002
    ..To explore the relationship between serum selenium and cervical cancer...
  42. pmc The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancer
    Denise L Stredrick
    Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 5060, USA
    Hum Mutat 27:538-44. 2006
    ..S49C, may be breast cancer susceptibility alleles. Because of their low frequency, even larger sample sizes are required to more firmly establish these associations...
  43. ncbi request reprint Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
    Int J Cancer 121:2532-8. 2007
    ..However, data suggested that common variation in TP53 or WDR79 could be associated with ER negative breast cancers...
  44. pmc Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies
    Xiaohong R Yang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Sciences, Rockville, MD 20852, USA
    J Natl Cancer Inst 103:250-63. 2011
    ..Previous studies have suggested that breast cancer risk factors are associated with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors...
  45. ncbi request reprint Intrauterine environment and breast cancer risk in a population-based case-control study in Poland
    Sue Kyung Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Int J Cancer 119:2136-41. 2006
    ..Our results add support to the growing evidence that some perinatal exposures may relate to breast cancer risk. Additional studies are needed to confirm associations and clarify the biologic mechanisms underlying these associations...
  46. ncbi request reprint Melanoma, thyroid, cervical, and colon cancer risk after use of fertility drugs
    Michelle D Althuis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Obstet Gynecol 193:668-74. 2005
    ..This study was undertaken to evaluate melanoma, thyroid, colon, and cervical cancer risks after clomiphene or gonadotropins...
  47. ncbi request reprint Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: a population-based analysis
    Mark E Sherman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
    Int J Cancer 121:1079-85. 2007
    ..07) for low PR and HER2 expression vs. OR = 1.78 (95% CI = 1.25-2.55) for high expression (p-heterogeneity = 0.001). PR and HER2 levels in breast cancer vary by BMI, suggesting a heterogeneous etiology for tumors related to these markers...
  48. ncbi request reprint Risks of cancer among a cohort of 23,935 men and women with osteoporosis
    Katherine A McGlynn
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, EPS Suite 550, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
    Int J Cancer 122:1879-84. 2008
    ..Conversely, factors associated with later onset osteoporosis may be related to a decreased risk of cancer...
  49. pmc Measurement of sex steroid hormones in breast adipocytes: methods and implications
    Roni T Falk
    Division of Cancer Epidemiology and Genetics, Epidemiology and Biostatistics Program, Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard S, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 17:1891-5. 2008
    ....
  50. pmc Genetic variation in the androgen receptor gene and endometrial cancer risk
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    Cancer Epidemiol Biomarkers Prev 18:585-9. 2009
    ..Results from our study, taken together with previously published studies, provide little evidence of a consistent association between common genetic variation in AR and endometrial cancer risk...
  51. pmc Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Marylan, United States of America
    PLoS Genet 4:e1000054. 2008
    ..Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment...
  52. ncbi request reprint Hormonal markers in breast cancer: coexpression, relationship with pathologic characteristics, and risk factor associations in a population-based study
    Xiaohong R Yang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892 7236, USA
    Cancer Res 67:10608-17. 2007
    ....
  53. ncbi request reprint Comparison of human papillomavirus genotypes, sexual, and reproductive risk factors of cervical adenocarcinoma and squamous cell carcinoma: Northeastern United States
    Sean F Altekruse
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 188:657-63. 2003
    ..We examined human papillomavirus genotypes and sexual and reproductive risk factors for cervical adenocarcinoma and squamous cell carcinoma...
  54. pmc Physical activity, sedentary behavior, and endometrial cancer risk in the NIH-AARP Diet and Health Study
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
    Int J Cancer 124:2139-47. 2009
    ..02). Associations with vigorous activities, which may interact with body mass index, suggest directions for future research to clarify underlying biologic mechanisms, including those relating to hormonal alterations...
  55. ncbi request reprint Recent trends in breast cancer incidence and mortality
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Mol Mutagen 39:82-8. 2002
    ..Continued analysis of international and intranational trends may reveal targets for multidisciplinary intervention and prevention efforts...
  56. ncbi request reprint Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Room 7076, Rockville, MD 20952 7234, USA
    Hum Genet 119:376-88. 2006
    ..Evaluation of potential underlying gene-gene interactions or associations in population subgroups will require even larger sample sizes...
  57. ncbi request reprint A debriefing session with a nutritionist can improve dietary assessment using food diaries
    Marie M Cantwell
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Nutr 136:440-5. 2006
    ..61 with a debriefing. Depending on the nutrients of interest, the inclusion of a debriefing can reduce the potential attenuation of RR in studies evaluating diet disease associations...
  58. ncbi request reprint Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal women
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 14:1724-31. 2005
    ..However, endometrial carcinoma risks among estrogen plus progestin users and among former unopposed estrogen users are not firmly established...
  59. pmc Active and passive cigarette smoking and the risk of endometrial cancer in Poland
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, Suite 520, Rockville, MD 20852, USA
    Eur J Cancer 46:690-6. 2010
    ..However, dose-response relationships with quantitative measures of active smoking or passive smoking remain less clear...
  60. ncbi request reprint Etiology of hormone receptor-defined breast cancer: a systematic review of the literature
    Michelle D Althuis
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7084, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 13:1558-68. 2004
    ..Large population-based studies of determinants of hormone receptor-defined breast cancers defined using state-of-the-art quantitative immunostaining methods are needed to clarify the role of ER/PR expression in breast cancer etiology...
  61. pmc Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 31:827-33. 2010
    ..Associations with variants in other genes have been suggested, but findings have been inconsistent...
  62. pmc Performance of common genetic variants in breast-cancer risk models
    Sholom Wacholder
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 5050, MSC 7244, Bethesda, MD 20892, USA
    N Engl J Med 362:986-93. 2010
    ..Genomewide association studies have identified multiple genetic variants associated with breast cancer. The extent to which these variants add to existing risk-assessment models is unknown...
  63. pmc Alcohol and endometrial cancer risk in the NIH-AARP diet and health study
    Hannah P Yang
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Int J Cancer 128:2953-61. 2011
    ..Our results do not support that alcohol is a strong contributor to endometrial cancer risk, but slight risk increases may prevail among some users or for selected tumor characteristics...
  64. ncbi request reprint Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan
    Allan Hildesheim
    Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rm 7062, Rockville, MD 20852, USA
    J Natl Cancer Inst 94:1780-9. 2002
    ..We used high-resolution HLA genotyping in a case-control study in Taiwan to systematically evaluate the association between various HLA alleles and NPC...
  65. doi request reprint Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics
    Jonine D Figueroa
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Breast Cancer Res Treat 121:727-35. 2010
    ..These results warrant analysis in studies of clinical outcomes accounting for age, ER status and treatment...
  66. ncbi request reprint Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Pharmacogenet Genomics 16:547-53. 2006
    ..The present study provides strong evidence against the existence of a substantial overall association between common genetic variation in CYP1B1 and breast cancer risk...
  67. ncbi request reprint Differences in risk factors for breast cancer molecular subtypes in a population-based study
    Xiaohong R Yang
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7014, 6120 Executive Boulevard, Bethesda, MD 20892 7236, USA
    Cancer Epidemiol Biomarkers Prev 16:439-43. 2007
    ..Results from this study have shown that breast cancer risk factors may vary by molecular subtypes identified in expression studies, suggesting etiologic, in addition to clinical, heterogeneity of breast cancer...
  68. pmc Nonsteroidal anti-inflammatory drug use and endometrial cancer risk in the NIH-AARP Diet and Health Study
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 2:466-72. 2009
    ..Overall, our data do not support an association between aspirin or NA-NSAID use and endometrial cancer risk...
  69. ncbi request reprint Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Hum Genet 121:483-90. 2007
    ..Additional studies are required to replicate these findings and to determine whether rs361525 is a causative SNP or is a marker of a causative SNP...
  70. ncbi request reprint Estimating age-specific breast cancer risks: a descriptive tool to identify age interactions
    William F Anderson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Executive Plaza South 8070, 6120 Executive Plaza Blvd, Rockville, MD 20892 7242, USA
    Cancer Causes Control 18:439-47. 2007
    ..Clarifying age-specific female breast cancer risks and interactions may provide important etiologic clues...
  71. pmc Timing of births and endometrial cancer risk in Swedish women
    Ruth M Pfeiffer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd EPS RM 8030, Bethesda, MD 20892 7244, USA
    Cancer Causes Control 20:1441-9. 2009
    ..0001) for women with > or =25 years since a last birth compared to women having given birth within 4 years. Our findings support that clearance of initiated cells during delivery may be important in endometrial carcinogenesis...
  72. ncbi request reprint Weight, height, and body mass index and risk for ovarian cancer in a cohort study
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville 20852 7234, MD
    Ann Epidemiol 16:869-76. 2006
    ..Reported associations between ovarian cancer and body size are inconsistent. We assessed ovarian cancer and anthropometry in the Breast Cancer Detection Demonstration Project Follow-Up Study...
  73. ncbi request reprint Menopausal hormone therapy and ovarian cancer risk in the National Institutes of Health-AARP Diet and Health Study Cohort
    James V Lacey
    Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, MDUSA
    J Natl Cancer Inst 98:1397-405. 2006
    ....
  74. ncbi request reprint Comprehensive assessment of genetic variation of catechol-O-methyltransferase and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology, National Cancer Institute, 6120 Executive Boulevard, EPS 7055, Rockville, MD 20852, USA
    Cancer Res 66:9781-5. 2006
    ..The suggestion of increased risk associated with a haplotype in the 3' UTR of COMT needs to be confirmed in independent study populations...
  75. pmc Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20952 7234, USA
    BMC Cancer 7:60. 2007
    ..We evaluated whether common genetic variation in SHBG and its 3' neighbor ATP1B2, in linkage disequilibrium, is associated with the risk of epithelial ovarian cancer...
  76. doi request reprint Genetic variation in CYP17 and endometrial cancer risk
    Mia M Gaudet
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Genet 123:155-62. 2008
    ..Further evaluation in consortia is necessary to confirm potential weak associations between common variation in CYP17 and endometrial cancer risk and to address the concern of publication bias...
  77. ncbi request reprint A case-control study of risk factors for invasive cervical cancer among U.S. women exposed to oncogenic types of human papillomavirus
    Tammy S Shields
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7234, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 13:1574-82. 2004
    ..It is particularly worth considering further why studies of different designs are inconsistent regarding the effect of oral contraceptive use...
  78. pmc Dietary fiber intake and risk of breast cancer in postmenopausal women: the National Institutes of Health-AARP Diet and Health Study
    Yikyung Park
    Divisions of Cancer Epidemiology and Genetics and Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
    Am J Clin Nutr 90:664-71. 2009
    ..Although dietary fiber has been hypothesized to lower risk of breast cancer by modulating estrogen metabolism, the association between dietary fiber intake and risk of breast cancer by hormone receptor status is unclear...
  79. ncbi request reprint Interrelationships between serum leptin, IGF-1, IGFBP3, C-peptide and prolactin and breast cancer risk in young women
    Roni T Falk
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Breast Cancer Res Treat 98:157-65. 2006
    ..With the possible exception of leptin, our findings do not suggest that these markers explain the breast cancer protection provided by obesity in premenopausal women...
  80. ncbi request reprint Increased risk of early-stage breast cancer related to consumption of sweet foods among women less than age 45 in the United States
    Nancy Potischman
    Division of Cancer Control and Population Studies, Centers for Disease Conztrol annd Prevention, Atlanta, GA, USA
    Cancer Causes Control 13:937-46. 2002
    ..To evaluate the associations of dietary macronutrients, food groups, and eating patterns with risk of breast cancer in a population-based case-control study...
  81. pmc Ovarian volumes among women with endometrial carcinoma: associations with risk factors and serum hormones
    Mark E Sherman
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
    Gynecol Oncol 107:431-5. 2007
    ..Accordingly, we assessed ovarian volumes in relation to serum sex hormone levels among post-menopausal women with endometrial carcinoma who participated in a multi-center case-control study...
  82. ncbi request reprint Breast cancers among very young premenopausal women (United States)
    Michelle D Althuis
    National Cancer Institute, Rockville, MD, USA
    Cancer Causes Control 14:151-60. 2003
    ..To assess risk factors for breast cancer among very young compared to older premenopausal women...
  83. ncbi request reprint Endometrial cancer and menopausal hormone therapy in the National Institutes of Health-AARP Diet and Health Study cohort
    James V Lacey
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
    Cancer 109:1303-11. 2007
    ....
  84. ncbi request reprint Insulin-like growth factors, insulin-like growth factor-binding proteins, and endometrial cancer in postmenopausal women: results from a U.S. case-control study
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, MSC 7234, Rockville, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 13:607-12. 2004
    ..To assess whether circulating insulin-like growth factor-1 (IGF-1), IGF-2, insulin-like growth factor-binding protein-1 (IGFBP-1), or IGFBP-3 were associated with endometrial cancer in postmenopausal women...
  85. ncbi request reprint Qualitative age interactions (or effect modification) suggest different cancer pathways for early-onset and late-onset breast cancers
    William F Anderson
    Biostatistics Branch, DHHS NIH NCI DCEG, EPS, Bethesda, MD 20892 7244, USA
    Cancer Causes Control 18:1187-98. 2007
    ..Prior to 1999-2000, breast cancer incidence rates had risen for decades, though more among older than younger women...
  86. ncbi request reprint Is male breast cancer similar or different than female breast cancer?
    William F Anderson
    NCI Division of Cancer Prevention, Bethesda, MD 20892 7317, USA
    Breast Cancer Res Treat 83:77-86. 2004
    ..To determine if male breast carcinogenesis was similar to its more common female counterpart, we compared incidence patterns among men and women with breast cancer...
  87. ncbi request reprint Tubal sterilization and risk of ovarian, endometrial and cervical cancer. A Danish population-based follow-up study of more than 65 000 sterilized women
    Susanne K Kjaer
    Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark
    Int J Epidemiol 33:596-602. 2004
    ..On the basis of a population-based cohort, we assessed the cancer risk, focusing on gynaecological cancers and pre-malignant lesions, among women with a previous tubal sterilization...
  88. ncbi request reprint Serum levels of sex hormones and breast cancer risk in premenopausal women: a case-control study (USA)
    Susan R Sturgeon
    Department of Biostatistics and Epidemiology, University of Massachusetts, 715 North Pleasant Street, Arnold House 407, Amherst, MA 01003 9304, USA
    Cancer Causes Control 15:45-53. 2004
    ..Observed differences between cases and controls subjects in serum levels of DHEA and luteal phase progesterone should be investigated further in large prospective studies...
  89. ncbi request reprint Distribution of human papillomavirus types 16 and 18 variants in squamous cell carcinomas and adenocarcinomas of the cervix
    Robert D Burk
    Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Cancer Res 63:7215-20. 2003
    ..Non-European HPV16 and/or HPV18 variants are commonly seen in AC. A possible hormonal mechanism is suggested to explain the observed findings...
  90. ncbi request reprint Risk of breast cancer classified by joint estrogen receptor and progesterone receptor status among women 20-44 years of age
    Julie A Britton
    Division of Environmental Health Science, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Epidemiol 156:507-16. 2002
    ..These findings only modestly support the hypothesis that hormonally related risk factors have differing relations with ER+PR+ versus ER-PR- tumors among younger women...
  91. doi request reprint Adulthood lifetime physical activity and breast cancer
    Beata Peplonska
    Department of Occupational and Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
    Epidemiology 19:226-36. 2008
    ..However, the effects of moderate activities, timing of activities, and intervening effects of other risk factors remain less clear...
  92. ncbi request reprint Nasopharyngeal carcinoma and genetic polymorphisms of DNA repair enzymes XRCC1 and hOGG1
    En Yu Cho
    Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei 10018, Taiwan
    Cancer Epidemiol Biomarkers Prev 12:1100-4. 2003
    ..5-177). Polymorphisms of the DNA repair genes hOGG1 (codon 326) and XRCC1 (codon 280) are associated with an altered risk of NPC. Carriers of multiple putative high-risk genotypes have the highest risk of developing NPC...
  93. ncbi request reprint Tobacco smoking, NAT2 acetylation genotype and breast cancer risk
    Jolanta Lissowska
    Department of Cancer Epidemiology and Prevention, Cancer Center and M Sklodowska Curie Institute of Oncology, Warsaw, Poland
    Int J Cancer 119:1961-9. 2006
    ..In conclusion, our data indicate that passive smoking is not associated with breast cancer risk; however, active smoking might be associated with an increased risk for early onset breast cancers...
  94. ncbi request reprint Recreational physical activity and survival among young women with breast cancer
    Page E Abrahamson
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA
    Cancer 107:1777-85. 2006
    ..Most epidemiologic studies report a reduced risk of developing breast cancer associated with higher levels of recreational physical activity, but little is known regarding its effect on prognosis...
  95. ncbi request reprint General and abdominal obesity and survival among young women with breast cancer
    Page E Abrahamson
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 15:1871-7. 2006
    ..22; 95% CI, 1.45-3.40). This study provides evidence that breast cancer survival is reduced among younger women with general or abdominal obesity...
  96. ncbi request reprint Risk for breast cancer among women with endometriosis
    Lisbeth Bertelsen
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen Ø, Denmark
    Int J Cancer 120:1372-5. 2007
    ..The increased risk associated with endometriosis among postmenopausal women may be due to common risk factors between postmenopausal endometriosis and breast cancer or an altered endogenous estrogen...
  97. ncbi request reprint Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: a population-based case-control study and meta-analyses
    Jolanta Lissowska
    Department of Cancer Epidemiology and Prevention, Cancer Center and M Sklodowska Curie Institute of Oncology, Warsaw, Poland
    Int J Cancer 120:2696-703. 2007
    ..In conclusion, this report does not support a substantial overall association between the evaluated polymorphisms in the one-carbon metabolism pathway and breast cancer risk...
  98. ncbi request reprint Factors associated with advanced disease stage at diagnosis in a population-based study of patients with newly diagnosed breast cancer
    Karin M E Hahn
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77230, USA
    Am J Epidemiol 166:1035-44. 2007
    ..Interventions targeting these factors could potentially lower the stage at diagnosis for African-American breast cancer patients and, in doing so, improve their survival and other outcomes...
  99. ncbi request reprint Occupation and breast cancer risk in Polish women: a population-based case-control study
    Beata Peplonska
    Department of Occupational and Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland
    Am J Ind Med 50:97-111. 2007
    ..The etiology of breast cancer is not well understood and the role of occupational exposures in breast carcinogenesis is still uncertain...
  100. ncbi request reprint Oral contraceptives and survival in breast cancer patients aged 20 to 54 years
    Katrina F Trivers
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS K 52, Atlanta, GA 30341, USA
    Cancer Epidemiol Biomarkers Prev 16:1822-7. 2007
    ....
  101. ncbi request reprint Cancer risk in menopausal women
    Carlo La Vecchia
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano
    Best Pract Res Clin Obstet Gynaecol 16:293-307. 2002
    ..The potential effect of 'natural' SERMs (phytoestrogens) on cancer risk remains undefined...