Research Topics
Genomes and Genes | L A BrintonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Modification of oral contraceptive relationships on breast cancer risk by selected factors among younger womenL A Brinton
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892, USA
Contraception 55:197-203. 1997....- Oral contraceptives as risk factors for cervical adenocarcinomas and squamous cell carcinomasJ V Lacey
National Cancer Institute, Bethesda, Maryland 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 8:1079-85. 1999.... - Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US womenS J Weinstein
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA
Cancer Causes Control 12:317-24. 2001..CONCLUSIONS: Serum homocysteine was strongly and significantly predictive of invasive cervical cancer risk. This association could reflect folate, B12 and/or B6 inadequacy, or genetic polymorphisms affecting one-carbon metabolism... 
Genetic variation in five genes important in telomere biology and risk for breast cancerS A Savage
Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Br J Cancer 97:832-6. 2007..Intriguing associations with variants in TERT among women with a family history of breast cancer warrant follow-up in independent studies...- Ethnicity and variation in breast cancer incidenceL A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 73:349-55. 1997..Many of the analyses among younger women (20-39 years) were limited by available numbers, but it appeared that very little disease occurrence in young black women was associated with the factors studied... - Reproductive risk factors for endometrial cancer among Polish womenL A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
Br J Cancer 96:1450-6. 2007..Alternative explanations for reproductive effects should be sought, including alterations in endogenous hormones... - Epidemiology of in situ and invasive breast cancer in women aged under 45H A Weiss
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892 7374, USA
Br J Cancer 73:1298-305. 1996.... - Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: results from a seroepidemiological case-control studyA Hildesheim
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
Obstet Gynecol 90:748-54. 1997..To examine whether human papillomavirus (HPV) type 16 is involved in the etiology of vulvar carcinomas... - Hormonal content and potency of oral contraceptives and breast cancer risk among young womenM D Althuis
Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 7084, EPS MSC 7234, Rockville, MD 20852 USA
Br J Cancer 88:50-7. 2003..Our findings suggest that newer low-potency/low oestrogen dose oral contraceptives may impart a lower risk of breast cancer than that associated with earlier high-potency/high-dose preparations... - Established breast cancer risk factors by clinically important tumour characteristicsM Garcia-Closas
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Rockville, MD 20852 7234, USA
Br J Cancer 95:123-9. 2006..In conclusion, these data support distinctive risk factor relationships by tumour characteristics of prognostic relevance. These findings might be useful in developing targeted prevention efforts... - Prolactin serum levels and breast cancer: relationships with risk factors and tumour characteristics among pre- and postmenopausal women in a population-based case-control study from PolandJ M Faupel-Badger
Cancer Prevention Fellowship Program, Center for Cancer Training, National Cancer Institute, 6120 Executive Blvd EPS, Suite 150E, MSC 7105, Bethesda, MD 20892, USA
Br J Cancer 103:1097-102. 2010.... - Tumor variants by hormone receptor expression in white patients with node-negative breast cancer from the surveillance, epidemiology, and end results databaseW F Anderson
Division of Cancer Prevention, Office of Special Population Research, and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7161, USA
J Clin Oncol 19:18-27. 2001..Determining whether hormone receptor expression represents one or more breast cancer phenotypes would have important paradigmatic and practical implications... - Characteristics of a population of women with breast implants compared with women seeking other types of plastic surgeryL A Brinton
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892 7234, USA
Plast Reconstr Surg 105:919-27; discussion 928-9. 2000.... - Estrogen replacement therapy and breast cancer survival in a large screening studyC Schairer
Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7374, USA
J Natl Cancer Inst 91:264-70. 1999..We examined breast cancer mortality among women who were diagnosed with axillary lymph node-negative and node-positive breast cancer according to the currency of estrogen use at diagnosis... - Associations between smoking and adenocarcinomas and squamous cell carcinomas of the uterine cervix (United States)J V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852 7234, USA
Cancer Causes Control 12:153-61. 2001..Few studies of smoking and cervical carcinoma have addressed the rare cervical adenocarcinomas or used DNA-based tests to control for human papillomavirus (HPV) infection... - Tubal ligation and risk of breast cancerL A Brinton
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892 7234, USA
Br J Cancer 82:1600-4. 2000..However, future investigations should include information on type of procedure performed (since this may relate to biologic effects) as well as other breast cancer risk factors... - CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in TaiwanA Hildesheim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
J Natl Cancer Inst 89:1207-12. 1997..We conducted a case-control study to investigate whether such variations affect the risk of developing nasopharyngeal cancer... - Low serum and red blood cell folate are moderately, but nonsignificantly associated with increased risk of invasive cervical cancer in U.S. womenS J Weinstein
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Nutr 131:2040-8. 2001..Thus, low serum and RBC folate were each moderately, but nonsignificantly, associated with increased invasive cervical cancer risk. These findings support a role for one-carbon metabolism in the etiology of cervical cancer... - Breast cancer risk in relation to amount of tissue removed during breast reduction operations in SwedenL A Brinton
National Cancer Institute, 6120 Executive Plaza South, Rm 7068, Bethesda, MD 20892 7234, USA
Cancer 91:478-83. 2001..The current investigation attempted to assess whether the reduction in breast cancer risk was related directly to the amount of breast tissue removed... - Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, ChinaG Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
Br J Cancer 102:1185-9. 2010..Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear... - Barrier and spermicidal contraceptive methods and risk of invasive cervical cancerA Hildesheim
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892
Epidemiology 1:266-72. 1990..The potential ability of spermicides to reduce cervical cancer risk by neutralizing viral agents warrants further attention... - Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialL M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Br J Cancer 101:178-84. 2009..We investigated meat subtypes, cooking practices, meat mutagens, iron, and subsequent breast cancer risk... - Skewed X chromosome inactivation and early-onset breast cancerJ P Struewing
Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
J Med Genet 43:48-53. 2006..We tested this hypothesis in a group of 235 breast cancer patients and 253 controls (mean age 45.8 years) from a larger population based case control study... - Ovarian cancer and menopausal hormone therapy in the NIH-AARP diet and health studyB Trabert
Department of Health and Human Services, Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Suite 550, Rockville, MD 20852, USA
Br J Cancer 107:1181-7. 2012..Women using unopposed estrogens during menopause are at increased risk of ovarian cancer. It is uncertain whether oestrogen plus progestin therapy exerts similar effects... - Collection of genomic DNA from adults in epidemiological studies by buccal cytobrush and mouthwashM Garcia-Closas
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 10:687-96. 2001.... - Past and present physical activity and endometrial cancer riskS R Sturgeon
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892
Br J Cancer 68:584-9. 1993..Future studies should attempt to obtain more detailed assessments of physical activity, including the intensity with which an individual engaged in an activity and the actual time involved in exertion... - Occupational exposure to wood, formaldehyde, and solvents and risk of nasopharyngeal carcinomaA Hildesheim
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 10:1145-53. 2001..Formaldehyde exposure is less clearly linked to NPC, whereas exposure to solvents is unlikely to be involved in NPC pathogenesis... - Effects of mammographic density and benign breast disease on breast cancer risk (United States)C Byrne
Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Cancer Causes Control 12:103-10. 2001..However, women with both proliferative benign breast disease and > or = 75% density were not at as high a risk of breast cancer due to the combination of effects (p = 0.002) as women with only one of these factors... - Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the diseaseN Hamajima
Cancer Research UK Epidemiology Unit, Gibson Building, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
Br J Cancer 87:1234-45. 2002.... - Long-term fracture risk among infertile women: a population-based cohort studyL J Melton
Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA
J Womens Health Gend Based Med 10:289-97. 2001.... - Characteristics associated with recent recreational exercise among women 20 to 44 years of ageJ A Britton
Division of Epidemiology, Joseph L Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Women Health 31:81-96. 2000..Though all women should be encouraged to participate in exercise, these findings identity subgroups of women that may need targeting when developing exercise intervention programs...