J L Brigman

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning
    Jonathan L Brigman
    Sections on Behavioral Science and Genetics, Synaptic Pharmacology, and Neuronal Structure, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland 20852, USA
    J Neurosci 30:4590-600. 2010
  2. pmc Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, MD 20852 9411, USA
    Cereb Cortex 20:1955-63. 2010
  3. pmc Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, Rockville, Maryland 20852 9411, USA
    Behav Pharmacol 20:204-9. 2009
  4. pmc Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    Learn Mem 15:50-4. 2008
  5. ncbi request reprint Stimulus specific deficit on visual reversal learning after lesions of medial prefrontal cortex in the mouse
    J L Brigman
    Department of Psychology, The George Washington University, 2125 G Street, NW, Washington, DC 20052, USA
    Behav Brain Res 187:405-10. 2008
  6. pmc Effects of adolescent fluoxetine treatment on fear-, anxiety- or stress-related behaviors in C57BL/6J or BALB/cJ mice
    Maxine Norcross
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 2N09, Rockville, MD, 20852 9411, USA
    Psychopharmacology (Berl) 200:413-24. 2008
  7. ncbi request reprint Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts
    Jonathan L Brigman
    Department of Psychology, George Washington University, Washington, DC 20052, USA
    Behav Neurosci 119:839-42. 2005
  8. ncbi request reprint Executive functions in the heterozygous reeler mouse model of schizophrenia
    Jonathan L Brigman
    Department of Psychology, George Washington University, Washington, DC 20052, USA
    Behav Neurosci 120:984-8. 2006

Detail Information

Publications10

  1. pmc Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning
    Jonathan L Brigman
    Sections on Behavioral Science and Genetics, Synaptic Pharmacology, and Neuronal Structure, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland 20852, USA
    J Neurosci 30:4590-600. 2010
    ....
  2. pmc Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, MD 20852 9411, USA
    Cereb Cortex 20:1955-63. 2010
    ..These findings could have important implications for understanding and treating cognitive inflexibility in neuropsychiatric disease...
  3. pmc Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, NIH, Rockville, Maryland 20852 9411, USA
    Behav Pharmacol 20:204-9. 2009
    ..These data add to evidence that murine measures of fear-like and anxiety-like traits reflect distinct constructs mediated by dissociable gene variants...
  4. pmc Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    Learn Mem 15:50-4. 2008
    ..The present findings demonstrate a significant and selective deficit in discrimination learning following loss of NR2A...
  5. ncbi request reprint Stimulus specific deficit on visual reversal learning after lesions of medial prefrontal cortex in the mouse
    J L Brigman
    Department of Psychology, The George Washington University, 2125 G Street, NW, Washington, DC 20052, USA
    Behav Brain Res 187:405-10. 2008
    ....
  6. pmc Effects of adolescent fluoxetine treatment on fear-, anxiety- or stress-related behaviors in C57BL/6J or BALB/cJ mice
    Maxine Norcross
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 2N09, Rockville, MD, 20852 9411, USA
    Psychopharmacology (Berl) 200:413-24. 2008
    ..Adverse effects of treatment with serotonin reuptake inhibitor (SRI) antidepressants have been reported in human adolescents. However, the long-term effects of chronic SRI treatment during adolescence in rodents remain unclear...
  7. ncbi request reprint Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts
    Jonathan L Brigman
    Department of Psychology, George Washington University, Washington, DC 20052, USA
    Behav Neurosci 119:839-42. 2005
    ..The fact that mice can be tested with stimuli and task sequences similar to those used with primates suggests that this method can be used to directly compare higher cognitive functions in diverse species...
  8. ncbi request reprint Executive functions in the heterozygous reeler mouse model of schizophrenia
    Jonathan L Brigman
    Department of Psychology, George Washington University, Washington, DC 20052, USA
    Behav Neurosci 120:984-8. 2006
    ..These results show that cognitive dysfunction may serve as a useful biomarker in mouse models of neuropsychiatric disease...