Affiliation: National Institutes of Health
- Naturally occurring amino acid substitutions in the HIV-2 ROD envelope glycoprotein regulate its ability to augment viral particle releaseStephan Bour
Viral Biochemistry Section, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 0460, USA
Virology 309:85-98. 2003....
- The HIV-1 Vpu protein: a multifunctional enhancer of viral particle releaseStephan Bour
Bioinformatics Core Facility, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4, Center Drive, Room 337, Bethesda, MD 20892 0460, USA
Microbes Infect 5:1029-39. 2003..This review focuses on presenting our current knowledge of the HIV-1-specific Vpu protein and its essential role in regulating viral particle release, viral load and expression of the CD4 receptor...
- DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysisBrad T Sherman
Laboratory of Immunopathogenesis and Bioinformatics, Clinical Services Program, SAIC Frederick, Inc, National Cancer Institute at Frederick, Frederick, MD 21702, USA
BMC Bioinformatics 8:426. 2007..Thus, a highly centralized and ready-to-use gene-annotation knowledgebase is in demand for high throughput gene functional analysis...
- dCAS: a desktop application for cDNA sequence annotationYongjian Guo
Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology and Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
Bioinformatics 25:1195-6. 2009..AVAILABILITY: The dCAS package is distributed freely. A cross-platform installer and associated sequence databases can be downloaded at: http://exon.niaid.nih.gov/applications.html...
- Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expressionKim Lien Nguyen
Viral Biochemistry Section, Laboratory of Molecular Microbiology, National Institutes of Allergy Diseases, Bethesda, MD 20892, USA
Virology 319:163-75. 2004....
- Expression, purification, and activities of full-length and truncated versions of the integral membrane protein Vpu from HIV-1Che Ma
Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
Protein Sci 11:546-57. 2002..The C-terminal alpha-helices modulate or promote the oligomerization of Vpu in the membrane and stabilize the conductive state of the channel, in addition to their involvement in CD4 degradation...
- Mutual functional destruction of HIV-1 Vpu and host TASK-1 channelKate Hsu
Institute of Molecular Cardiobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Mol Cell 14:259-67. 2004..This virus-host interaction may influence HIV-1/AIDS progression, as well as electrical signaling in infected host tissues...
- Specific interaction of CXCR4 with CD4 and CD8alpha: functional analysis of the CD4/CXCR4 interaction in the context of HIV-1 envelope glycoprotein-mediated membrane fusionStephane Basmaciogullari
Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA
Virology 353:52-67. 2006..The CD4/CXCR4 and CD8alpha/CXCR4 interactions may thus be involved in cellular signaling pathways shared by the CD4 and CD8alpha molecules...