Catharine M Bosio

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    J Immunol 178:4538-47. 2007
  2. ncbi Lung environment determines unique phenotype of alveolar macrophages
    Amanda M Guth
    Departments of Clinical Sciences, Colorado State University, Ft Collins, USA
    Am J Physiol Lung Cell Mol Physiol 296:L936-46. 2009
  3. ncbi Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, 80523, USA
    J Immunol 175:6792-801. 2005
  4. ncbi Early interaction of Yersinia pestis with APCs in the lung
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
    J Immunol 175:6750-6. 2005
  5. ncbi The presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo
    Jennifer C Chase
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Infect Immun 78:154-67. 2010
  6. ncbi Innate and adaptive immunity to Francisella
    Karen L Elkins
    Laboratory of Mycobacterial Diseases and Cellular Immunology, Division of Bacterial, Parasitic, and Allergenic Products, CBER U S FDA, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1105:284-324. 2007
  7. ncbi Innate and adaptive immune responses to an intracellular bacterium, Francisella tularensis live vaccine strain
    Karen L Elkins
    Laboratory of Mycobacteria, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, 1401 Rockville Pike, HFM 431, Rockville, MD 20852, USA
    Microbes Infect 5:135-42. 2003
  8. ncbi Ebola and Marburg virus-like particles activate human myeloid dendritic cells
    Catharine M Bosio
    Clinical Research Management, Frederick, MD 21702, USA
    Virology 326:280-7. 2004
  9. ncbi Ebola virus-like particles protect from lethal Ebola virus infection
    Kelly L Warfield
    US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
    Proc Natl Acad Sci U S A 100:15889-94. 2003
  10. ncbi NKp30-dependent cytolysis of filovirus-infected human dendritic cells
    Claudette L Fuller
    United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
    Cell Microbiol 9:962-76. 2007

Collaborators

Detail Information

Publications11

  1. ncbi Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    J Immunol 178:4538-47. 2007
    ..tularensis, Schu4 induced broad immunosuppression within the first few days after aerosol infection. This difference may explain the increased virulence of type A strains compared with their more attenuated counterparts...
  2. ncbi Lung environment determines unique phenotype of alveolar macrophages
    Amanda M Guth
    Departments of Clinical Sciences, Colorado State University, Ft Collins, USA
    Am J Physiol Lung Cell Mol Physiol 296:L936-46. 2009
    ....
  3. ncbi Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, 80523, USA
    J Immunol 175:6792-801. 2005
    ....
  4. ncbi Early interaction of Yersinia pestis with APCs in the lung
    Catharine M Bosio
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
    J Immunol 175:6750-6. 2005
    ..pestis. Depletion of these airway cells by Y. pestis may therefore be one strategy the organism uses to overcome pulmonary defenses following inhalation of the organism...
  5. ncbi The presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo
    Jennifer C Chase
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Infect Immun 78:154-67. 2010
    ..Thus, the presence of this receptor may aid in control of virulent F. tularensis infections at early, but not late, stages of infection...
  6. ncbi Innate and adaptive immunity to Francisella
    Karen L Elkins
    Laboratory of Mycobacterial Diseases and Cellular Immunology, Division of Bacterial, Parasitic, and Allergenic Products, CBER U S FDA, Bethesda, Maryland, USA
    Ann N Y Acad Sci 1105:284-324. 2007
    ..Thus a number of known proinflammatory and Th-1 T cell related components of the immune system combat this virulent bacterium; no doubt others remain to be discovered...
  7. ncbi Innate and adaptive immune responses to an intracellular bacterium, Francisella tularensis live vaccine strain
    Karen L Elkins
    Laboratory of Mycobacteria, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, 1401 Rockville Pike, HFM 431, Rockville, MD 20852, USA
    Microbes Infect 5:135-42. 2003
    ..Here we review this infection model, which provides a convenient means of studying protective immune mechanisms not only for Francisella, but also for the large and important class of intracellular pathogens...
  8. ncbi Ebola and Marburg virus-like particles activate human myeloid dendritic cells
    Catharine M Bosio
    Clinical Research Management, Frederick, MD 21702, USA
    Virology 326:280-7. 2004
    ..Thus, our findings suggest that unlike EBOV and MARV, VLPs are effective stimulators of DCs and have potential in enhancing innate and adaptive immune responses...
  9. ncbi Ebola virus-like particles protect from lethal Ebola virus infection
    Kelly L Warfield
    US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
    Proc Natl Acad Sci U S A 100:15889-94. 2003
    ..Together, our data suggest that eVLPs represent a promising vaccine candidate for protection against Ebola virus infections and a much needed tool to examine the genesis and nature of immune responses to Ebola virus...
  10. ncbi NKp30-dependent cytolysis of filovirus-infected human dendritic cells
    Claudette L Fuller
    United States Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA
    Cell Microbiol 9:962-76. 2007
    ..Further elucidation of the biology of NK cell activation, specifically natural cytotoxicity receptors like NKp30 and NKp46, promises to aid our understanding of microbial pathology...
  11. ncbi Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation
    Catharine M Bosio
    United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21702-5011, USA
    J Infect Dis 188:1630-8. 2003
    ..These findings may explain the profound virulence of EBOV and MARV--DCs are disabled, and an effective early host response is delayed by the necessary reliance on less-efficient secondary mechanisms...