Research Topics
Species | Gerd BobeSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Effect of sample preparation, length of time, and sample size on quantification of total lipids from bovine liverBurim N Ametaj
Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, USA
J Agric Food Chem 51:2105-10. 2003..Sample sizes of at least 150 mg gave precise estimates. The results demonstrate that sample preparation, time length of different steps of the extraction procedure, and sample size affect quantification of total lipid from bovine liver...
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob miceGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
Nutr Cancer 60:373-81. 2008..04; bean residue 67%, P=0.01; bean extract 87%, P=0.0003. These results suggest that both the soluble and the insoluble fraction of the extract contribute to the cancer-protective effect of cooked navy beans...
Short communication: estimates of genetic variation of milk fatty acids in US Holstein cowsG Bobe
Nutritional Physiology, Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 91:1209-13. 2008....- Non-invasive detection of fatty liver in dairy cows by digital analyses of hepatic ultrasonogramsGerd Bobe
Department of Electrical and Computer Engineering, Iowa State University, Ames IA 50011, USA
J Dairy Res 75:84-9. 2008..Therefore, ultrasound imaging followed by digital analysis of sonograms has potential to non-invasively detect fatty liver and estimate liver triacylglycerol content... - Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob miceRoycelynn A Mentor-Marcel
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, 1050 Boyles Street, Frederick, MD 21702, USA
Cancer Prev Res (Phila) 2:60-9. 2009..Changes in a subset of inflammation-associated serum proteins and colon gene expression may serve as response indicators of dietary attenuation of colon carcinogenesis... - Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trialGerd Bobe
Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 3:764-75. 2010..Our results suggest that serum IL-6 may serve as a risk indicator and as a response indicator to dietary flavonols for colorectal cancer prevention... - Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
Int J Cancer 130:1649-59. 2012..04). To conclude, dietary lignan and proanthocyanidin consumption were not generally related to colorectal adenoma recurrence; however, high lignan intake may increase the risk of adenoma recurrence in women... - Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?Gerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Eur J Cancer Prev 20:86-95. 2011..In conclusion, our results suggest that IL SNPs, in combination with a flavonol-rich diet or decreased serum IL, may lower the risk of adenoma recurrence... - Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010..Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer... - Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patientsRoycelynn A Mentor-Marcel
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland, USA
Nutr Cancer 64:820-5. 2012..52) observed in colorectal tissue taken within the same week. Plasma concentrations of GM-CSF and IL-8 may serve as noninvasive indicators to monitor tissue response to berry-based interventions for CRC... - Physical and sensory properties of dairy products from cows with various milk fatty acid compositionsShe Chen
Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, USA
J Agric Food Chem 52:3422-8. 2004..Thus, selection of cows for milk fatty acid composition can be used to produce dairy products that are probably more healthful and have a softer texture... - Bioactive food components, inflammatory targets, and cancer preventionYoung S Kim
Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA
Cancer Prev Res (Phila) 2:200-8. 2009..Unquestionably, the societal benefits of using foods and their components to prevent chronic inflammation and associated complications, including cancer, are enormous... - Butter composition and texture from cows with different milk fatty acid compositions fed fish oil or roasted soybeansG Bobe
Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 90:2596-603. 2007..Thus, selecting cows with a more health-promoting milk fatty acid composition and feeding supplemental RSB can be used in combination to produce butter that has a consumer-friendly texture and a healthful fatty acid profile... - Short communication: Composition of milk protein and milk fatty acids is stable for cows differing in genetic merit for milk productionG Bobe
Animal Breeding and Genetic Group, Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 90:3955-60. 2007..Therefore, selection for milk yield decreased concentrations of milk protein and milk fat but had little effect on composition of milk protein and milk fatty acids... - Flavonoid consumption and esophageal cancer among black and white men in the United StatesGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, MD 21702 1201, USA
Int J Cancer 125:1147-54. 2009..Some protective effects were evident in flavonoid subclasses and population subgroups. In white men, foods rich in anthocyanidins may have chemopreventive effects in EAC and those rich in isoflavonoids may do so in ESCC... - Dietary flavonoids and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, National Cancer Institute Frederick, Room 110, Building 576, Frederick, MD 21702 1201, USA
Cancer Epidemiol Biomarkers Prev 17:1344-53. 2008..Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence... - Texture of butter from cows with different milk fatty acid compositionsG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 86:3122-7. 2003..Thus, phenotypic variation in milk fatty acid composition among cows fed the same diet is sufficient to produce butter with different textural properties... - Potential treatment of fatty liver with 14-day subcutaneous injections of glucagonG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 86:3138-47. 2003..5 yr, but not in younger multiparous cows. Our results document that subcutaneous injections of glucagon have the potential to decrease the degree of fatty liver in older dairy cows in early lactation... - Prevention of fatty liver in transition dairy cows by subcutaneous injections of glucagonR A Nafikov
Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 89:1533-45. 2006..These results indicate that subcutaneous glucagon injections can prevent fatty liver in transition dairy cows without causing major production and metabolite disturbances... - Effects of lipid supplementation on the yield and composition of milk from cows with different beta-lactoglobulin phenotypesG Bobe
Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 92:197-203. 2009..2% of additional tallow increases milk yield without affecting milk component content and milk protein composition... - Effects of glucagon infusions on protein and amino acid composition of milk from dairy cowsG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 92:130-8. 2009..91 +/- 0.32%). Glucagon had little impact on milk AA composition except an increase in glycine (0.26 +/- 0.11%). The results suggest that milk protein synthesis is regulated by many factors including AA and glucose availability... - Effects of exogenous glucagon on lipids in lipoproteins and liver of lactating dairy cowsG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 86:2895-903. 2003.... - Exogenous glucagon effects on health and reproductive performance of lactating dairy cows with mild fatty liverG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, 313 Kildee Hall, Ames, IA 50011 3150, USA
Anim Reprod Sci 102:194-207. 2007..From these results, we suggest that mild fatty liver is detrimental to health and reproduction of dairy cows and, furthermore, that exogenous glucagon decreases some of these detrimental effects... - Metabolic responses of lactating dairy cows to single and multiple subcutaneous injections of glucagonG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 86:2072-81. 2003..These results document that both single and multiple injections of 5 mg of glucagon over 14 d consistently improve the carbohydrate status of dairy cows and decrease concentrations of plasma NEFA and BHBA... - Glucagon increases hepatic mRNA concentrations of ureagenic and gluconeogenic enzymes in early-lactation dairy cowsG Bobe
Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 92:5092-9. 2009..Our results suggest that hepatic gene expression of key ureagenic and gluconeogenic enzymes in early-lactation dairy cows is responsive to hormonal regulation by glucagon... - Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention TrialG Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Building 576, Room 101, 1050 Boyles Street, Frederick, MD 21702, USA
Br J Cancer 103:1453-61. 2010..Flavonols, bioactive compounds found in plant-based foods and beverages, may inhibit colorectal neoplasms partly by attenuating inflammation... - Chronic metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or bothM A Osman
Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 93:3505-12. 2010.... - Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cowsG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011-3150, USA
J Dairy Sci 87:3105-24. 2004..Such advances hopefully will make fatty liver a problem of the past... - Acute metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or bothM A Osman
Department of Animal Science, Iowa State University, Ames 50011, USA
J Dairy Sci 91:3311-22. 2008..This suggests that glucagon and glycerol, when co-administered, act to decrease the likelihood of metabolism-related syndrome development in dairy cows... - Flavonoid intake and risk of pancreatic cancer in male smokers (Finland)Gerd Bobe
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, 6120 Executive Boulevard, Room 3022, Rockville, MD 20852 7232, USA
Cancer Epidemiol Biomarkers Prev 17:553-62. 2008..Our data suggest that a flavonoid-rich diet may decrease pancreatic cancer risk in male smokers not consuming supplemental alpha-tocopherol and/or beta-carotene... - Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindacGerd Bobe
Department of Food Science and Human Nutrition, Bioactive Natural Products and Phytoceuticals, Department of Horticulture, and National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 44824, USA
J Agric Food Chem 54:9322-8. 2006..These results suggest that a dietary combination of tart cherry anthocyanins and sulindac is more protective against colon cancer than sulindac alone...