Gerd Bobe

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effect of sample preparation, length of time, and sample size on quantification of total lipids from bovine liver
    Burim N Ametaj
    Department of Animal Science, Iowa State University, Ames, Iowa 50011 3150, USA
    J Agric Food Chem 51:2105-10. 2003
  2. pmc Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
    Nutr Cancer 60:373-81. 2008
  3. doi request reprint Short communication: estimates of genetic variation of milk fatty acids in US Holstein cows
    G Bobe
    Nutritional Physiology, Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 91:1209-13. 2008
  4. doi request reprint Non-invasive detection of fatty liver in dairy cows by digital analyses of hepatic ultrasonograms
    Gerd Bobe
    Department of Electrical and Computer Engineering, Iowa State University, Ames IA 50011, USA
    J Dairy Res 75:84-9. 2008
  5. pmc Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice
    Roycelynn A Mentor-Marcel
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, 1050 Boyles Street, Frederick, MD 21702, USA
    Cancer Prev Res (Phila) 2:60-9. 2009
  6. pmc Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trial
    Gerd Bobe
    Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Prev Res (Phila) 3:764-75. 2010
  7. pmc Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention Trial
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
    Int J Cancer 130:1649-59. 2012
  8. pmc Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Eur J Cancer Prev 20:86-95. 2011
  9. pmc Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010
  10. pmc Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients
    Roycelynn A Mentor-Marcel
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland, USA
    Nutr Cancer 64:820-5. 2012

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Effect of sample preparation, length of time, and sample size on quantification of total lipids from bovine liver
    Burim N Ametaj
    Department of Animal Science, Iowa State University, Ames, Iowa 50011 3150, USA
    J Agric Food Chem 51:2105-10. 2003
    ..Sample sizes of at least 150 mg gave precise estimates. The results demonstrate that sample preparation, time length of different steps of the extraction procedure, and sample size affect quantification of total lipid from bovine liver...
  2. pmc Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland 21702, USA
    Nutr Cancer 60:373-81. 2008
    ..04; bean residue 67%, P=0.01; bean extract 87%, P=0.0003. These results suggest that both the soluble and the insoluble fraction of the extract contribute to the cancer-protective effect of cooked navy beans...
  3. doi request reprint Short communication: estimates of genetic variation of milk fatty acids in US Holstein cows
    G Bobe
    Nutritional Physiology, Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 91:1209-13. 2008
    ....
  4. doi request reprint Non-invasive detection of fatty liver in dairy cows by digital analyses of hepatic ultrasonograms
    Gerd Bobe
    Department of Electrical and Computer Engineering, Iowa State University, Ames IA 50011, USA
    J Dairy Res 75:84-9. 2008
    ..Therefore, ultrasound imaging followed by digital analysis of sonograms has potential to non-invasively detect fatty liver and estimate liver triacylglycerol content...
  5. pmc Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice
    Roycelynn A Mentor-Marcel
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, 1050 Boyles Street, Frederick, MD 21702, USA
    Cancer Prev Res (Phila) 2:60-9. 2009
    ..Changes in a subset of inflammation-associated serum proteins and colon gene expression may serve as response indicators of dietary attenuation of colon carcinogenesis...
  6. pmc Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trial
    Gerd Bobe
    Center for Cancer Research, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Prev Res (Phila) 3:764-75. 2010
    ..Our results suggest that serum IL-6 may serve as a risk indicator and as a response indicator to dietary flavonols for colorectal cancer prevention...
  7. pmc Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention Trial
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
    Int J Cancer 130:1649-59. 2012
    ..04). To conclude, dietary lignan and proanthocyanidin consumption were not generally related to colorectal adenoma recurrence; however, high lignan intake may increase the risk of adenoma recurrence in women...
  8. pmc Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Eur J Cancer Prev 20:86-95. 2011
    ..In conclusion, our results suggest that IL SNPs, in combination with a flavonol-rich diet or decreased serum IL, may lower the risk of adenoma recurrence...
  9. pmc Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010
    ..Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer...
  10. pmc Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients
    Roycelynn A Mentor-Marcel
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, Frederick, Maryland, USA
    Nutr Cancer 64:820-5. 2012
    ..52) observed in colorectal tissue taken within the same week. Plasma concentrations of GM-CSF and IL-8 may serve as noninvasive indicators to monitor tissue response to berry-based interventions for CRC...
  11. ncbi request reprint Physical and sensory properties of dairy products from cows with various milk fatty acid compositions
    She Chen
    Department of Animal Science, Iowa State University, Ames, Iowa 50011 3150, USA
    J Agric Food Chem 52:3422-8. 2004
    ..Thus, selection of cows for milk fatty acid composition can be used to produce dairy products that are probably more healthful and have a softer texture...
  12. pmc Bioactive food components, inflammatory targets, and cancer prevention
    Young S Kim
    Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, USA
    Cancer Prev Res (Phila) 2:200-8. 2009
    ..Unquestionably, the societal benefits of using foods and their components to prevent chronic inflammation and associated complications, including cancer, are enormous...
  13. ncbi request reprint Butter composition and texture from cows with different milk fatty acid compositions fed fish oil or roasted soybeans
    G Bobe
    Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 90:2596-603. 2007
    ..Thus, selecting cows with a more health-promoting milk fatty acid composition and feeding supplemental RSB can be used in combination to produce butter that has a consumer-friendly texture and a healthful fatty acid profile...
  14. ncbi request reprint Short communication: Composition of milk protein and milk fatty acids is stable for cows differing in genetic merit for milk production
    G Bobe
    Animal Breeding and Genetic Group, Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 90:3955-60. 2007
    ..Therefore, selection for milk yield decreased concentrations of milk protein and milk fat but had little effect on composition of milk protein and milk fatty acids...
  15. doi request reprint Flavonoid consumption and esophageal cancer among black and white men in the United States
    Gerd Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute Frederick, MD 21702 1201, USA
    Int J Cancer 125:1147-54. 2009
    ..Some protective effects were evident in flavonoid subclasses and population subgroups. In white men, foods rich in anthocyanidins may have chemopreventive effects in EAC and those rich in isoflavonoids may do so in ESCC...
  16. pmc Dietary flavonoids and colorectal adenoma recurrence in the Polyp Prevention Trial
    Gerd Bobe
    Laboratory of Cancer Prevention, National Cancer Institute Frederick, Room 110, Building 576, Frederick, MD 21702 1201, USA
    Cancer Epidemiol Biomarkers Prev 17:1344-53. 2008
    ..Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence...
  17. ncbi request reprint Texture of butter from cows with different milk fatty acid compositions
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 86:3122-7. 2003
    ..Thus, phenotypic variation in milk fatty acid composition among cows fed the same diet is sufficient to produce butter with different textural properties...
  18. ncbi request reprint Potential treatment of fatty liver with 14-day subcutaneous injections of glucagon
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 86:3138-47. 2003
    ..5 yr, but not in younger multiparous cows. Our results document that subcutaneous injections of glucagon have the potential to decrease the degree of fatty liver in older dairy cows in early lactation...
  19. ncbi request reprint Prevention of fatty liver in transition dairy cows by subcutaneous injections of glucagon
    R A Nafikov
    Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 89:1533-45. 2006
    ..These results indicate that subcutaneous glucagon injections can prevent fatty liver in transition dairy cows without causing major production and metabolite disturbances...
  20. doi request reprint Effects of lipid supplementation on the yield and composition of milk from cows with different beta-lactoglobulin phenotypes
    G Bobe
    Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 92:197-203. 2009
    ..2% of additional tallow increases milk yield without affecting milk component content and milk protein composition...
  21. doi request reprint Effects of glucagon infusions on protein and amino acid composition of milk from dairy cows
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 92:130-8. 2009
    ..91 +/- 0.32%). Glucagon had little impact on milk AA composition except an increase in glycine (0.26 +/- 0.11%). The results suggest that milk protein synthesis is regulated by many factors including AA and glucose availability...
  22. ncbi request reprint Effects of exogenous glucagon on lipids in lipoproteins and liver of lactating dairy cows
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 86:2895-903. 2003
    ....
  23. ncbi request reprint Exogenous glucagon effects on health and reproductive performance of lactating dairy cows with mild fatty liver
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, 313 Kildee Hall, Ames, IA 50011 3150, USA
    Anim Reprod Sci 102:194-207. 2007
    ..From these results, we suggest that mild fatty liver is detrimental to health and reproduction of dairy cows and, furthermore, that exogenous glucagon decreases some of these detrimental effects...
  24. ncbi request reprint Metabolic responses of lactating dairy cows to single and multiple subcutaneous injections of glucagon
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 86:2072-81. 2003
    ..These results document that both single and multiple injections of 5 mg of glucagon over 14 d consistently improve the carbohydrate status of dairy cows and decrease concentrations of plasma NEFA and BHBA...
  25. doi request reprint Glucagon increases hepatic mRNA concentrations of ureagenic and gluconeogenic enzymes in early-lactation dairy cows
    G Bobe
    Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 92:5092-9. 2009
    ..Our results suggest that hepatic gene expression of key ureagenic and gluconeogenic enzymes in early-lactation dairy cows is responsive to hormonal regulation by glucagon...
  26. pmc Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention Trial
    G Bobe
    Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Building 576, Room 101, 1050 Boyles Street, Frederick, MD 21702, USA
    Br J Cancer 103:1453-61. 2010
    ..Flavonols, bioactive compounds found in plant-based foods and beverages, may inhibit colorectal neoplasms partly by attenuating inflammation...
  27. doi request reprint Chronic metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both
    M A Osman
    Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 93:3505-12. 2010
    ....
  28. ncbi request reprint Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows
    G Bobe
    Nutritional Physiology Group, Department of Animal Science, Iowa State University, Ames 50011 3150, USA
    J Dairy Sci 87:3105-24. 2004
    ..Such advances hopefully will make fatty liver a problem of the past...
  29. doi request reprint Acute metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both
    M A Osman
    Department of Animal Science, Iowa State University, Ames 50011, USA
    J Dairy Sci 91:3311-22. 2008
    ..This suggests that glucagon and glycerol, when co-administered, act to decrease the likelihood of metabolism-related syndrome development in dairy cows...
  30. doi request reprint Flavonoid intake and risk of pancreatic cancer in male smokers (Finland)
    Gerd Bobe
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, 6120 Executive Boulevard, Room 3022, Rockville, MD 20852 7232, USA
    Cancer Epidemiol Biomarkers Prev 17:553-62. 2008
    ..Our data suggest that a flavonoid-rich diet may decrease pancreatic cancer risk in male smokers not consuming supplemental alpha-tocopherol and/or beta-carotene...
  31. ncbi request reprint Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac
    Gerd Bobe
    Department of Food Science and Human Nutrition, Bioactive Natural Products and Phytoceuticals, Department of Horticulture, and National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 44824, USA
    J Agric Food Chem 54:9322-8. 2006
    ..These results suggest that a dietary combination of tart cherry anthocyanins and sulindac is more protective against colon cancer than sulindac alone...