Research Topics
| James M BjorkSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Serotonin 2a receptor T102C polymorphism and impaired impulse controlJames M Bjork
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, Houston, Texas 77030, USA
Am J Med Genet 114:336-9. 2002..These preliminary data suggest that the T102C 5-HT2a receptor polymorphism may be a marker for impaired behavior control-perhaps in the context of psychiatric disorder history...
Commission error rates on a continuous performance test are related to deficits measured by the Benton Visual Retention TestDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 77030, USA
Assessment 10:3-12. 2003..These results may be explained by a shared association between processes of impulsivity and other deficits of executive control that may interfere with successful performance of the Benton...
Striatal functional alteration in adolescents characterized by early childhood behavioral inhibitionAmanda E Guyer
Emotional Development and Affective Neuroscience Branch, National Institute of Mental Health, National Institutes of Health NIH, Bethesda, Maryland 20892, USA
J Neurosci 26:6399-405. 2006....
Mesolimbic recruitment by nondrug rewards in detoxified alcoholics: effort anticipation, reward anticipation, and reward deliveryJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
Hum Brain Mapp 33:2174-88. 2012....
Psychopathic tendencies and mesolimbic recruitment by cues for instrumental and passively obtained rewardsJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
Biol Psychol 89:408-15. 2012..These data indicate that in psychiatrically healthy controls, individuals with greater endorsement of psychopathic tendencies show more robust neurophysiological and behavioral signatures of incentive motivation...
Psychosocial problems and recruitment of incentive neurocircuitry: exploring individual differences in healthy adolescentsJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
Dev Cogn Neurosci 1:570-77. 2011..These findings extend previous reports demonstrating that in adolescents, individual differences in reactivity of motivational neurocircuitry relate to different facets of impulsivity or externalizing behaviors...
Striatal sensitivity to reward deliveries and omissions in substance dependent patientsJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 42:1609-21. 2008..Rather, SDP may instead have increased limbic system sensitivity to reward and loss delivery, consistent with the role of impulsivity in SD...
Incentive-elicited striatal activation in adolescent children of alcoholicsJames M Bjork
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
Addiction 103:1308-19. 2008..We tested whether parental alcoholism, which confers risk of SD, is correlated with altered recruitment of ventral striatum (VS) by non-drug rewards in adolescence...
Delay discounting correlates with proportional lateral frontal cortex volumesJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland 20892, USA
Biol Psychiatry 65:710-3. 2009..Might individual differences in frontocortical gray matter morphology be related to preference for immediate reward?..
Does traumatic brain injury increase risk for substance abuse?James M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland 20892, USA
J Neurotrauma 26:1077-82. 2009..In this review, we conclude that little is known regarding the directionality of TBI increasing drug abuse, and that collaborative research in this area is critically needed...
Incentive-elicited mesolimbic activation and externalizing symptomatology in adolescentsJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health NIH, Bethesda, MD 20892, USA
J Child Psychol Psychiatry 51:827-37. 2010..Reward processing has been indexed by recruitment of incentive-motivational neurocircuitry of the ventral striatum (VS), including nucleus accumbens (NAcc)...
Adolescents, adults and rewards: comparing motivational neurocircuitry recruitment using fMRIJames M Bjork
Division of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 5:e11440. 2010....
Developmental differences in posterior mesofrontal cortex recruitment by risky rewardsJames M Bjork
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892, USA
J Neurosci 27:4839-49. 2007....
Anticipating instrumentally obtained and passively-received rewards: a factorial fMRI investigationJames M Bjork
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, United States
Behav Brain Res 177:165-70. 2007..Ventromesial striatum was activated by joint requirement for an instrumental response together with uncertain (but not certain) reward...
Impulsivity in abstinent alcohol-dependent patients: relation to control subjects and type 1-/type 2-like traitsJames M Bjork
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Room 3C 103, Bethesda, MD 20892, USA
Alcohol 34:133-50. 2004....
Incentive-elicited brain activation in adolescents: similarities and differences from young adultsJames M Bjork
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism National Institutes of Health, Bethesda, Maryland 20892 7003, USA
J Neurosci 24:1793-802. 2004..These results suggest that adolescents selectively show reduced recruitment of motivational but not consummatory components of reward-directed behavior...
Cross-sectional volumetric analysis of brain atrophy in alcohol dependence: effects of drinking history and comorbid substance use disorderJames M Bjork
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism NIH, 10 Center Drive, Room 3C 103, Bethesda, MD 20892, USA
Am J Psychiatry 160:2038-45. 2003..The authors assessed whether individual differences in drinking history as well as lifetime incidence of comorbid cocaine or marijuana use disorder underlie differential patterns of brain atrophy in subjects with alcohol dependence...
Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent patientsJames M Bjork
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892, USA
Drug Alcohol Depend 95:115-28. 2008..These data suggest that SDP are characterized by a combination of: (a) striatal hypersensitivity to reward, and (b) under-recruitment of the specialized conflict-monitoring circuitry of the PMC when reward entails potential penalties...
Why we like to drink: a functional magnetic resonance imaging study of the rewarding and anxiolytic effects of alcoholJodi M Gilman
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892, USA
J Neurosci 28:4583-91. 2008..These results show that the acute pharmacological rewarding and anxiolytic effects of alcohol can be measured with fMRI...
Parental alcohol use and brain volumes in early- and late-onset alcoholicsJodi M Gilman
Section of Brain Electrophysiology and Imaging, Laboratory of Clinical and Translational Studies, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Biol Psychiatry 62:607-15. 2007....
Imaging brain response to reward in addictive disordersDaniel W Hommer
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892, USA
Ann N Y Acad Sci 1216:50-61. 2011..It is likely that aspects of brain function described by both the impulsivity and reward-deficiency hypotheses contribute to the pathophysiology of addiction...
Behavioral impulsivity paradigms: a comparison in hospitalized adolescents with disruptive behavior disordersDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030 3406, USA
J Child Psychol Psychiatry 44:1145-57. 2003..As a result, comparisons between measures are difficult, with little consensus regarding which method may be most sensitive to individual impulsivity differences of different populations...
Amphetamine modulates human incentive processingBrian Knutson
Department of Psychology, Stanford University, CA 94305, USA
Neuron 43:261-9. 2004..These findings suggest that therapeutic effects of amphetamine on incentive processing may involve reducing the difference between anticipation of gains and losses...
Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristicsDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030, USA
J Gen Psychol 130:5-21. 2003..e., BIS) was correlated with commission errors for parents, but not for adolescents. The findings of this study support the use of an objective behavioral measure of impulsivity to assess familial relationships of impulsivity...
Two models of impulsivity: relationship to personality traits and psychopathologyAlan C Swann
Department of Psychiatry, University of Texas Medical School, Houston, Texas, USA
Biol Psychiatry 51:988-94. 2002..The relationship appears stronger, however, for rapid-response impulsivity, as measured by the IMT/DMT. Laboratory and personality measures of impulsivity appear to be related to risk of psychopathology...
