Research Topics
| R J BiggarSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Human immunodeficiency virus type 1 infection in twin pairs infected at birthRobert J Biggar
Viral Epidemiology Branch, National Cancer Institute, Bethesda, Bethesda, MD 20852, USA
J Infect Dis 186:281-5. 2002..Thus, given infection, factors intrinsic to HIV-1 are more important than host genetics in viral evolution...
AIDS-related cancers in the era of highly active antiretroviral therapyR J Biggar
Viral Epidemiology Branch National Cancer Institute, Bethesda, Maryland, USA
Oncology (Williston Park) 15:439-48; discussion 448-9. 2001....
Kaposi's sarcoma and non-Hodgkin's lymphoma following the diagnosis of AIDS. Multistate AIDS/Cancer Match Study GroupR J Biggar
Viral Epidemiology, National Cancer Institute, Bethesda, MD, USA
Int J Cancer 68:754-8. 1996..In summary, the risk of KS following another AIDS-defining illness is strikingly high, more in white men than in black men, and the risks of KS and, especially, NHL appear to increase with time from AIDS...
Risk of T-cell lymphomas in persons with AIDSR J Biggar
Viral Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA
J Acquir Immune Defic Syndr 26:371-6. 2001..HIV-related immunodeficiency could be important, but differences between the population developing AIDS and the general population (e. g., immigration from the Caribbean region for ATLL) might independently increase T-cell lymphoma risk...
Risk of cancer in children with AIDS. AIDS-Cancer Match Registry Study GroupR J Biggar
VEB NCI, 6120 Executive Blvd, Room 8014, Bethesda, MD 20852
JAMA 284:205-9. 2000..Population-based data on cancers associated with acquired immunodeficiency syndrome (AIDS) in children are lacking...
Virus levels in untreated African infants infected with human immunodeficiency virus type 1R J Biggar
Viral Epidemiology Branch, National Cancer Institute, National Institute of Allergy and Infectious Diseases, Rockville, MD 20862, USA
J Infect Dis 180:1838-43. 1999..Most (87%) CB-positive infants were infected before labor onset, since virus levels greatly exceeded those expected in their mothers...
Predictors and impact of losses to follow-up in an HIV-1 perinatal transmission cohort in MalawiJ P Ioannidis
HIV Research Branch, Division of AIDS, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
Int J Epidemiol 28:769-75. 1999..A better understanding of the characteristics and the impact of women and children lost to follow-up is needed...
Identifying human herpesvirus 8 infection: performance characteristics of serologic assaysE A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
J Acquir Immune Defic Syndr 23:346-54. 2000..Overall, assays performed adequately for use in most epidemiologic investigations, but wider applications will require improved tests...
Spectrum of AIDS-associated malignant disordersJ J Goedert
Viral Epidemiology Branch, National Cancer Institute, Rockville, MD, USA
Lancet 351:1833-9. 1998..To clarify which types of cancer result from AIDS, we compared the cancer experiences of people with AIDS with those of the general population by matching population-based cancer and AIDS registries in the USA and Puerto Rico...
Zoster incidence in human immunodeficiency virus-infected hemophiliacs and homosexual men, 1984-1997. District of Columbia Gay Cohort Study. Multicenter Hemophilia Cohort StudyE A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20822, USA
J Infect Dis 180:1784-9. 1999..During the 14 years of follow-up, zoster incidence declined 9% per year. This trend occurred despite decreasing CD4 cell counts and was unexplained by zidovudine or acyclovir use...
HIV transmission through breastfeeding: a study in MalawiP G Miotti
Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD, USA
JAMA 282:744-9. 1999..Understanding the risk of human immunodeficiency virus (HIV) transmission through breastfeeding is essential for advising HIV-infected mothers and formulating public health policy recommendations...
Human herpesvirus 8 in Brazilian Amerindians: a hyperendemic population with a new subtypeR J Biggar
Viral Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA nih gov
J Infect Dis 181:1562-8. 2000..Transmission is probably oral rather than sexual. The limited genetic pool in isolated groups may permit more frequent transmission of a virus with a low prevalence in heterogeneous populations...
Trends in HIV incidence among young adults in the United StatesP S Rosenberg
Biostatistics Branch, National Cancer Institute, Bethesda, MD 20892, USA
JAMA 279:1894-9. 1998..Behaviors that result in potential exposure to human immunodeficiency virus (HIV) usually begin in adolescence or young adulthood, but trends in HIV incidence in young people remain unclear...
Viral levels in newborn African infants undergoing primary HIV-1 infectionR J Biggar
Viral Epidemiology Branch, NCI, Bethesda, Maryland, USA
AIDS 15:1311-3. 2001....
Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndromeM Frisch
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
J Natl Cancer Inst 92:1500-10. 2000..The purpose of our study was to determine if the high frequency of these cancers is due to lifestyle factors associated with both HPV and HIV infections or to immunosuppression following HIV infection...
Trends in human immunodeficiency virus type 1 (HIV-1) load among HIV-1-infected children with hemophiliaE A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852, USA
J Infect Dis 184:364-8. 2001..In conclusion, those subjects had virus load trends similar to those in adults. Early virus loads were lower than those in vertically infected infants, which suggests that factors changing soon after birth affect viral replication...
Effect of knowledge of human immunodeficiency virus infection status on sexual activity among homosexual menS Z Wiktor
Viral Epidemiology Section, National Cancer Institute, Bethesda, Maryland 20892
J Acquir Immune Defic Syndr 3:62-8. 1990..Overall, only 32% of American and 53% of Danish homosexual men were practicing completely safe sex. We suggest that education to promote the need for awareness of one's own and one's partner's HIV status should be stressed...
Latent class analysis of human herpesvirus 8 assay performance and infection prevalence in sub-saharan Africa and MaltaE A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Int J Cancer 88:1003-8. 2000..Prevalence was also high in Botswana (87% in Sans, an indigenous group, and 76% in Bantus), though Kaposi's sarcoma is not common, suggesting that additional co-factors besides HHV-8 are needed for development of Kaposi's sarcoma...
Changing patterns of tonsillar squamous cell carcinoma in the United StatesM Frisch
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Causes Control 11:489-95. 2000..Tonsillar squamous cell carcinoma (SCC) may differ etiologically from other oral cancers. The aim of this study was to provide a detailed description of the incidence patterns of tonsillar SCC in the United States...
A serosurvey of Haemophilus ducreyi, syphilis, and herpes simplex virus type 2 and their association with human immunodeficiency virus among female sex workers in Lagos, NigeriaA J Dada
Viral Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20852, USA
Sex Transm Dis 25:237-42. 1998..ducreyi, Treponema pallidum, and herpes simplex virus type 2 (HSV-2) antibodies among female sex workers (FSWs) and their association with human immunodeficiency virus (HIV) antibody status...
Antibody to human retroviruses among drug users in three east coast American cities, 1972-1976R J Biggar
Viral Epidemiology Section, National Cancer Institute, Bethesda, Maryland 20852
J Infect Dis 163:57-63. 1991..Therefore, HTLV (probably HTLV-II) has been a common infection of drug users for many years but adverse outcomes following infection were not demonstrated...
Solid tumors after chronic lymphocytic leukemiaM Hisada
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Blood 98:1979-81. 2001..91) and for cancers of the stomach (O/E = 1.76) and bladder (O/E = 1.52) among women. Additional investigations of cancers after CLL are needed to explore the role of immunologic impairment and/or other etiologic influences...
