Sonja M Best

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Caspase activation during virus infection: more than just the kiss of death?
    Sonja M Best
    Laboratory of Persistent Viral Diseases, NIAID, NIH, Rocky Mountain Labs, Hamilton, MT 59840, USA
    Virology 320:191-4. 2004
  2. ncbi Viral subversion of apoptotic enzymes: escape from death row
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
    Annu Rev Microbiol 62:171-92. 2008
  3. ncbi Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
  4. ncbi Pathogenesis of aleutian mink disease parvovirus and similarities to b19 infection
    S M Best
    Laboratory of Persistent Viral Diseases, NIAID, NIH Rocky Mountain Laboratories, 903 S Fourth St, Hamilton, MT 59840, USA
    J Vet Med B Infect Dis Vet Public Health 52:331-4. 2005
  5. ncbi Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
  6. ncbi Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain
    Gregory S Park
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 81:6936-46. 2007
  7. ncbi Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
  8. ncbi Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
  9. ncbi Two mink parvoviruses use different cellular receptors for entry into CRFK cells
    Gregory S Park
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 340:1-9. 2005
  10. ncbi Caspase cleavage of the nonstructural protein NS1 mediates replication of Aleutian mink disease parvovirus
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana 59840, USA
    J Virol 77:5305-12. 2003

Collaborators

Detail Information

Publications17

  1. ncbi Caspase activation during virus infection: more than just the kiss of death?
    Sonja M Best
    Laboratory of Persistent Viral Diseases, NIAID, NIH, Rocky Mountain Labs, Hamilton, MT 59840, USA
    Virology 320:191-4. 2004
  2. ncbi Viral subversion of apoptotic enzymes: escape from death row
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
    Annu Rev Microbiol 62:171-92. 2008
    ..Examination of these interactions contributes to our understanding of both virus pathogenesis and the regulation of apoptotic enzymes in normal cellular functions...
  3. ncbi Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
    ..Because NS5 may interfere with both innate and acquired immune responses to virus infection, this protein may have a significant role in viral pathogenesis...
  4. ncbi Pathogenesis of aleutian mink disease parvovirus and similarities to b19 infection
    S M Best
    Laboratory of Persistent Viral Diseases, NIAID, NIH Rocky Mountain Laboratories, 903 S Fourth St, Hamilton, MT 59840, USA
    J Vet Med B Infect Dis Vet Public Health 52:331-4. 2005
    ..Thus, a study of the regulation of NS1 expression and its interactions with cell signalling pathways may lead to increased understanding of the restricted replication of these two viruses, and perhaps of persistent infection...
  5. ncbi Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
    ..Thus, our data implicate a role for E, M, NS3, NS4A and NS4B in host adaptation and pathogenicity of tick-borne flaviviruses...
  6. ncbi Identification of residues critical for the interferon antagonist function of Langat virus NS5 reveals a role for the RNA-dependent RNA polymerase domain
    Gregory S Park
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA
    J Virol 81:6936-46. 2007
    ..This insight into the mechanism underlying flavivirus IFN evasion strategies will facilitate the design of antiviral therapeutics that potentiate the action of IFN during infection...
  7. ncbi Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
    ..This work will provide a more detailed understanding of early events in virus infection and their impact on flavivirus pathogenesis...
  8. ncbi Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
    ....
  9. ncbi Two mink parvoviruses use different cellular receptors for entry into CRFK cells
    Gregory S Park
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 340:1-9. 2005
    ..The use of two different receptors by MEV and ADV to infect the same cell line is yet another difference between these two parvoviruses that may contribute to their unique pathogenesis in mink...
  10. ncbi Caspase cleavage of the nonstructural protein NS1 mediates replication of Aleutian mink disease parvovirus
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana 59840, USA
    J Virol 77:5305-12. 2003
    ..The requirement for caspase activity during permissive replication suggests that limitation of caspase activation and apoptosis in vivo may be a novel approach to restricting virus replication...
  11. ncbi TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase
    R Travis Taylor
    Innate Immunity and Pathogenesis Unit, Laboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    Cell Host Microbe 10:185-96. 2011
    ..The specificity of TRIM79α for TBEV reveals a remarkable ability of the innate IFN response to discriminate between closely related flaviviruses...
  12. ncbi Caspase activation is required for permissive replication of Aleutian mink disease parvovirus in vitro
    Sonja M Best
    Laboratory of Persistent Viral Diseases, NIAID, NIH, Rocky Mountain Laboratories, 903 South Fourth Street, Hamilton, Montana 59840, USA
    Virology 292:224-34. 2002
    ..If ADV infection of cells in vivo fails to initiate caspase activation, the requirement of caspase activity for replication may not be met, thus providing a possible mechanism for persistent, restricted infection...
  13. ncbi Antagonism of type I interferon responses by new world hantaviruses
    Jessica R Levine
    Rocky Mountain Laboratories, Hamilton, MT 59840, USA
    J Virol 84:11790-801. 2010
    ..These data suggest that IFN antagonism strategies by hantaviruses are quite variable, even between species with similar disease phenotypes, and may help to better elucidate species-specific pathogenesis...
  14. ncbi Assessing ubiquitination of viral proteins: Lessons from flavivirus NS5
    R Travis Taylor
    Innate Immunity and Pathogenesis Unit, Laboratory of Virology, Rocky Mountain Laboratories, DIR, NIAID, NIH, 903 S 4th St, Hamilton, MT 59840, USA
    Methods 55:166-71. 2011
    ....
  15. ncbi The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling
    Maudry Laurent-Rolle
    Laboratory of Virology, Rocky Mountain Laboratories, 903 S Fourth St, Hamilton, MT 59840, USA
    J Virol 84:3503-15. 2010
    ..Thus, a naturally occurring mutation is associated with the function of NS5 in IFN antagonism and may influence virulence of WNV field isolates...
  16. ncbi Identification of aleutian mink disease parvovirus capsid sequences mediating antibody-dependent enhancement of infection, virus neutralization, and immune complex formation
    M E Bloom
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA
    J Virol 75:11116-27. 2001
    ..The observation that antibodies against a single target peptide in the ADV capsid can mediate both neutralization and ADE may explain the failure of capsid-based vaccines...
  17. ncbi Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection
    Kristin L McNally
    Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 S Fourth St, Hamilton, MT 59840, USA
    Ticks Tick Borne Dis 3:18-26. 2012
    ..Further analysis of these transcripts may identify salivary factors that affect the transmission or replication of tick-borne flaviviruses...