David M Berman
Affiliation: National Institutes of Health
- Profiling the activity of G proteins in patient-derived tissues by rapid affinity-capture of signal transduction proteins (GRASP)David M Berman
Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Proteomics 4:812-8. 2004..GRASP represents an advance in the field of proteomics as it detects protein interactions present in cells as they exist in their native tissue microenvironment...
- A functional polymorphism in RGS6 modulates the risk of bladder cancerDavid M Berman
Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Res 64:6820-6. 2004..These data provide the first evidence that RGS proteins may be important modulators of cancer risk and validate RGS6 as a target for further study...
- Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanomaSteven A Rosenberg
Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 175:6169-76. 2005..Further, the induction of even high levels of antitumor T cells may be insufficient to alter tumor progression...
- Measuring tissue-based biomarkers by immunochromatography coupled with reverse-phase lysate microarrayMartin J Romeo
Laboratory of Pathology, Surgery Branch, and Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
Clin Cancer Res 12:2463-7. 2006..Furthermore, RPM is currently limited by time-consuming microdissection and low amounts of evaluable protein lysates...
- Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanomaMark E Dudley
Surgery Branch, National Cancer Institute, NIH, CRC 3 3940, 10 Center Dr MSC 1201, Bethesda MD 20892 1202, USA
J Clin Oncol 23:2346-57. 2005..We investigated the combination of lymphodepleting chemotherapy followed by the adoptive transfer of autologous tumor reactive lymphocytes for the treatment of patients with refractory metastatic melanoma...
- Loss of S100 antigenicity in metastatic melanomaDara L Aisner
Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892, USA
Hum Pathol 36:1016-9. 2005..We conclude that all S100-negative melanomas could be correctly identified by negative workup for carcinoma, lymphoma, and sarcoma plus (1) GP100/MART-1 immunoreactivity and/or (2) prior documentation of melanoma...
- Skin reactions in a subset of patients with stage IV melanoma treated with anti-cytotoxic T-lymphocyte antigen 4 monoclonal antibody as a single agentSamer H Jaber
Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 1908, USA
Arch Dermatol 142:166-72. 2006....
- A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican AmericansJian Gu
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Cancer 106:2716-24. 2006..Recently, the authors reported that 3 single-nucleotide polymorphisms (SNPs) in 2 members of the RGS family were associated with significant reductions in the risk of cancer...
- Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative imagesJeffrey D Seidman
Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
Hum Pathol 35:918-33. 2004..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
- Molecular genetic analysis of ovarian serous cystadenomasEric J Cheng
Department of Pathology, The Johns Hopkins University, Baltimore, MD 21231, USA
Lab Invest 84:778-84. 2004..Accordingly, it appears that serous cystadenomas develop as a hyperplastic expansion from epithelial inclusions with a clonal/neoplastic transformation occurring in a subset of them...
- Lysophosphatidic acid down-regulates stress fibers and up-regulates pro-matrix metalloproteinase-2 activation in ovarian cancer cellsThuy Vy Do
Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago Illinois, USA
Mol Cancer Res 5:121-31. 2007..Collectively, these results were consistent with a model in which LPA stimulates the metastatic dissemination of EOC cells by initiating loss of adhesion and metalloproteinase activation...
- Risk factors for the development of bronchiectasis in HIV-infected childrenDavid M Berman
Division of Pediatric Infectious Disease and Special Immunology, University of Miami School of Medicine, Jackson Memorial Medical Center, Miami, Florida 33701, USA
Pediatr Pulmonol 42:871-5. 2007..3%), respectively (P-value = 0.005). HIV-1 infected children with a history of recurrent pneumonia, profound immuno-suppression (CDC immunologic category 3), and LIP appear to have a higher risk of developing bronchiectasis...