Sasisekhar Bennuru

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Pathog 5:e1000688. 2009
  2. pmc Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 0425, USA
    Lymphat Res Biol 7:215-9. 2009
  3. pmc Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Trop Med Hyg 83:884-90. 2010
  4. pmc Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 108:9649-54. 2011
  5. pmc Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Negl Trop Dis 3:e410. 2009
  6. pmc Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization
    Helton C Santiago
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Allergy Clin Immunol 130:248-56.e9. 2012
  7. pmc Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion
    Alexis Boyd
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Infect Immun 81:1420-9. 2013
  8. pmc Structural differences between human proteins and aero- and microbial allergens define allergenicity
    Helton da Costa Santiago
    The Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e40552. 2012
  9. pmc Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis
    Helton C Santiago
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
    J Allergy Clin Immunol 127:479-86. 2011

Collaborators

Detail Information

Publications9

  1. pmc Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    PLoS Pathog 5:e1000688. 2009
    ..The data suggest that filarial parasites directly induce lymphangiogenesis and lymphatic differentiation and provide insight into the mechanisms underlying the pathology seen in lymphatic filariasis...
  2. pmc Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892 0425, USA
    Lymphat Res Biol 7:215-9. 2009
    ....
  3. pmc Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Trop Med Hyg 83:884-90. 2010
    ....
  4. pmc Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 108:9649-54. 2011
    ..Parasite sex- and stage-specific protein expression identified those pathways related to parasite differentiation and demonstrates stage-specific expression by the Bm endosymbiont Wolbachia as well...
  5. pmc Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling
    Sasisekhar Bennuru
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Negl Trop Dis 3:e410. 2009
    ..This proteomic analysis extends our knowledge of the ES and provides insight into the host-parasite interaction...
  6. pmc Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization
    Helton C Santiago
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Allergy Clin Immunol 130:248-56.e9. 2012
    ..The extensive similarities between helminth proteins and allergens are thought to contribute to helminth-driven allergic sensitization...
  7. pmc Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion
    Alexis Boyd
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Infect Immun 81:1420-9. 2013
    ..Our data suggest that failure by LC to initiate an inflammatory response to the invasive stage of filarial parasites may be a strategy for immune evasion by the filarial parasite...
  8. pmc Structural differences between human proteins and aero- and microbial allergens define allergenicity
    Helton da Costa Santiago
    The Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 7:e40552. 2012
    ..Our results suggest that allergenicity may be associated with the relative "uniqueness" of an antigen, i.e. immunogenicity, while similarity would lead to immunological tolerance...
  9. pmc Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis
    Helton C Santiago
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
    J Allergy Clin Immunol 127:479-86. 2011
    ..The hygiene hypothesis suggests that parasitic infection modulates host immune responses and decreases atopy. Other data suggest parasitic infections may induce allergic responsiveness...