L Michelle Bennett
Affiliation: National Institutes of Health
- Collaboration and team science: from theory to practiceL Michelle Bennett
National Heart, Lung, and Blood Institute, MD, USA
J Investig Med 60:768-75. 2012..Successful scientific collaborations have strong leaders who are self-aware and are mindful of the many elements critical for supporting the science at the center of the effort...
- Cigarette smoking during pregnancy: chromosome translocations and phenotypic susceptibility in mothers and newbornsL Michelle Bennett
Physical and Life Sciences Directorate, L 452, Lawrence Livermore National Laboratory, Livermore, CA 94550, United States
Mutat Res 696:81-8. 2010..However, peripheral lymphocytes in pregnant women are more susceptible to genetic damage than peripheral lymphocytes in newborns...
- Flor-Essence herbal tonic does not inhibit mammary tumor development in Sprague Dawley ratsL Michelle Bennett
Center for Cancer Research, NCI, NIH, Bethesda, MD 20852, USA
Breast Cancer Res Treat 88:87-93. 2004..Flor-Essence tonic is a complex mixture of herbal extracts used by cancer patients because of anecdotal evidence that it can treat or prevent disease...
- Essiac and Flor-Essence herbal tonics stimulate the in vitro growth of human breast cancer cellsKristen S Kulp
Biosciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
Breast Cancer Res Treat 98:249-59. 2006..In this study, we evaluated Flor-Essence and Essiac for their effects on the growth of human tumor cells in culture...
- PhIP carcinogenicity in breast cancer: computational and experimental evidence for competitive interactions with human estrogen receptorBrian J Bennion
Biosciences Directorate, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94551, USA
Chem Res Toxicol 18:1528-36. 2005..We propose that the mechanism for the tissue-specific carcinogenicity seen in the rat breast tumors and the presumptive human breast cancer associated with the consumption of well-done meat maybe mediated by this receptor activation...
- Cancer susceptibility of mice with a homozygous deletion in the COOH-terminal domain of the Brca2 geneKimberly A McAllister
Laboratory of Women s Health, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27709, USA
Cancer Res 62:990-4. 2002..Given their substantial viability and cancer predisposition, these mutant mice will be useful to further define the role of the COOH-terminal Brca2 domain in tumorigenesis both in vivo and in vitro...
- Distinct effects of calorie restriction and exercise on mammary gland gene expression in C57BL/6 miceMichela Padovani
Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
Cancer Prev Res (Phila) 2:1076-87. 2009..Thus, CR and EX seem to exert their effects on mammary carcinogenesis through distinct pathways...
- Impact of environmental exposures on the mutagenicity/carcinogenicity of heterocyclic aminesJames S Felton
Biology and Biotechnology Research Program, L 452, Lawrence Livermore National Laboratory, Livermore, CA 94551, USA
Toxicology 198:135-45. 2004..Numerous environmental chemicals found in food or the atmosphere can impact the exposure, metabolism, and cell proliferation response of heterocyclic amines...
- Pregnancy and protection from hormonally associated tumor developmentJ Carl Barrett
Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
Epidemiology 14:139-40. 2003
- Identification of mammary carcinogens in rodent bioassaysL Michelle Bennett
Genetics of Cancer Group, Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California 94551, USA
Environ Mol Mutagen 39:150-7. 2002..More information is needed on the effects of chemicals to which humans are exposed and the manner by which they influence breast cancer risks...
- Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutationKimberly A McAllister
National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27711, USA
Toxicol Pathol 34:187-98. 2006..In addition, these findings include extensive in vivo data demonstrating that germline Brca2 and p53 mutations cooperatively affect animal survivals, tumor susceptibilities, and tumor onsets...
- Linking laboratory and clinical research: the development of molecularly targeted therapeutics inside the national cancer institute center for cancer researchJ Carl Barrett
National Cancer Institute Center for Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA
Clin Adv Hematol Oncol 1:302-6. 2003..Its infrastructure supports the iterative flow of information from the bench to the bedside and from the bedside to the bench, expediting the delivery of molecularly based therapeutics to cancer patients...
- A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic linesAndrea Bilger
McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
Genetics 167:859-66. 2004..Thus, distal chromosome 1 carries one or more genes that are sufficient to confer susceptibility to liver cancer...
- Reducing disparities in the burden of cancer: the role of patient navigatorsTisha Fowler
National Cancer Institute Cancer Prevention and Control, Center for Health Promotion and Prevention, University of Texas School of Public Health, Houston, Texas, United States of America
PLoS Med 3:e193. 2006
- The partnership between breast cancer advocates and scientistsJanice H Platner
National Breast Cancer Coalition, Washington, DC 20036, USA
Environ Mol Mutagen 39:102-7. 2002..Breast cancer advocates trained by NBCC have partnered with the scientific community and individual scientists to improve the peer review, design, and implementation of breast cancer research...